Phylogenetic reconstruction of cancer cell populations remains challenging. There is a particular lack of tools that deconvolve clones based on copy number aberration analyses of multiple tumor biopsies separated in time and space from the same patient. This has hampered investigations of tumors rich in aneuploidy but few point mutations, as in many childhood cancers and high-risk adult cancer. He

BACKGROUND: Many of those who suffer from a first acute coronary event (CE) die suddenly during the day of the event, most of them die outside hospital. Poor lung function is a strong predictor of future cardiac events; however, it is unknown whether the pattern of lung function impairment differs for the prediction of sudden cardiac death (SCD) versus non-fatal CEs. We examined measures of lung f

The Scanian Economic-Demographic Database (SEDD) at the Centre for Economic Demography (CED), Lund University was built to answer questions derived from previous research using macro data from 1749 onwards. It includes longitudinal micro data for a regional sample of rural, semi-urban, and urban parishes in southern Sweden from 1646 to 1968 for approximately 175,000 individuals. In addition to the

Milk polar lipids provide choline, ethanolamine, and polyunsaturated fatty acids, which are needed for the growth and plasticity of the tissues in a suckling child. They may also inhibit cholesterol absorption by interacting with cholesterol during micelle formation. They may also have beneficial luminal, mucosal, and metabolic effects in both the neonate and the adult. The milk fat globule membra

OBJECTIVE: To assess the association of cardiometabolic risk factors with hospitalisation or death due to COVID-19 in the general population.DESIGN, SETTING AND PARTICIPANTS: Swedish population-based cohort including 29 955 participants.EXPOSURES: Cardiometabolic risk factors assessed between 2014 and 2018.MAIN OUTCOME MEASURES: Hospitalisation or death due to COVID-19, as registered in nationwide

Seventeen resurfacing arthroplasties undertaken in 13 patients with severe hip arthritis are described. The youngest patient was 14 years and the mean age 23 years. The average follow-up time is 2 years. In one patient, pain-free for 7 months, the femoral cup slipped and revision into total hip replacement was easily performed. The remaining patients are pain-free, have increased motion, a better

This paper interrogates how contesting state and marketplace ideologies in Sweden negotiates the construction of gender transgression in the mar- ketplace. There is always an incessant ideological battle among the differ- ent sides of a society – among the traditionalist and the more progressive, among those who embraces change and those who attempt to conserve corrupting the natural order. Betwee