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Children diagnosed with right ventricle outflow tract (RVOT) anomalies require surgical repair early in life, reoperations and lifelong follow-up. The aim is to comprehensively describe their health related quality of life (HRQoL) and to assess the agreement in this regard between children and parents. New publication in Front. Cardiovasc. Med.

https://www.lupop.lu.se/article/health-related-quality-life-children-earlier-surgical-repair-right-ventricular-outflow-tract - 2025-09-15

Charnley, McKee and Ling, arguably the pioneers of Total Hip Replacement (THR), all recommended that there should be some sort of register for hip replacements. Perceptively, Sir John wrote in 1972: “Serious consideration should be given to establishing a Central Register to keep a finger on the pulse of total implant surgery on a nation-wide basis.” However, it was Peter Herberts and Lennart Ahnf

https://www.lupop.lu.se/article/how-registry-data-can-improve-outcomes-joint-replacement-seminal-paper - 2025-09-15

Women with lower levels of serum selenium (Se) may have a worse survival in breast cancer than women with higher levels, despite no difference in incidence of the disease. Our study was conducted to test whether Se is associated with the aggressiveness of breast tumors. Both the risk of having a tumor characteristic associated with worse prognosis, as well as the overall and breast cancer‐specific

https://www.lupop.lu.se/article/prediagnostic-serum-selenium-levels-relation-breast-cancer-survival-and-tumor-characteristics - 2025-09-15

Patients were significantly better (p < 0.001) than their physicians in estimating the average probability of heart failure compared with actual outcome data (14% vs. 24%, outcome 15%), AMI (16% vs. 26%, outcome 8%), and stroke (15% vs. 25%, outcome 11%). Patients were significantly worse (p < 0.001) at estimating the average probability of death (10% vs. 18%, actual outcome 20%). Neither the pati

https://www.lupop.lu.se/article/do-patients-or-their-physicians-more-accurately-assess-long-term-risk-associated-hypertension - 2025-09-15

This study used multiple national register data from Sweden. During the 11-year follow-up period between 2005 and 2015, data from 1,167,449 men and 542,606 women, aged 20–55 years, were accessible for inclusion in this analysis. Incidence of obesity was identified based on a diagnosis of obesity during the follow-up period derived from clinical register data. Neighborhood availability of fast-food

https://www.lupop.lu.se/article/fast-food-outlets-physical-activity-facilities-and-obesity-among-adults-nationwide-longitudinal - 2025-09-15

A total of 413 000 people with T2D aged <66 years, comprising 4.9 million person‐years, was included. The crude proportion with any absence was higher among those with T2D compared to controls (47% vs. 26%) in the index year, and the median (IQR) number of days was higher (223 [77;359] vs. 196 [59;352]) if any absence. Regression analyses showed that complications per se were a key driver of days

https://www.lupop.lu.se/article/days-absent-work-result-complications-associated-type-2-diabetes-evidence-20-years-linked-national - 2025-09-15

The term “fracture cascade” refers to the sequence of fragility fractures resulting from the increased fracture risk that occurs with aging and following fractures. Here, we evaluate the sequence of previous fractures in women aged 55 to 90 years presenting with a fragility fracture and subsequent (12 to 24 months) fracture incidence. In this retrospective, observational study, women aged 55 to 90

https://www.lupop.lu.se/article/history-previous-fracture-and-imminent-fracture-risk-swedish-women-aged-55-90-years-presenting - 2025-09-15

Socioeconomic status is an important determinant of health, the measurement of which is of great significance to population health research. However, individual-level socioeconomic factors are absent from much health administrative data, resulting in widespread use of area-level measures in their place. This study aims to clarify the role of individual- and area-level socioeconomic status in Ontar

https://www.lupop.lu.se/article/agreement-between-area-and-individual-level-income-measures-population-based-cohort-implications - 2025-09-15

This was a retrospective cohort study carried out in eight health facilities in two regions of Ethiopia. Adolescents (age 10–14 and 15–19 year) and children (age 0–9 year) enrolled in chronic HIV care between 2005 and 2013 constituted the study population. We reviewed the individual patient charts between March and June 2014 and updated the data on the status of each patient through December 2015.

https://www.lupop.lu.se/article/adolescents-living-hiv-are-higher-risk-death-and-loss-follow-care-analysis-cohort-data-eight-health - 2025-09-15

Central arterial stiffness is a surrogate of cardiovascular risk and predicts cardiovascular mortality. Apolipoprotein B lipoproteins are also established cardiovascular risk factors. It is not known whether specific lipoprotein subclasses measured in the Malmö Diet and Cancer Study and previously shown to be associated with coronary heart disease also predict arterial stiffening after a mean peri

https://www.lupop.lu.se/article/lipoprotein-particle-predictors-arterial-stiffness-after-17-years-follow-malmo-diet-and-cancer-study - 2025-09-15

Excess weight gain throughout adulthood can lead to adverse clinical outcomes and are influenced by complex factors that are difficult to measure in free-living individuals. Metabolite profiling offers an opportunity to systematically discover new predictors for weight gain that are relatively easy to measure compared to traditional approaches. New publication in PLOS ONE

https://www.lupop.lu.se/article/using-metabolite-profiling-construct-and-validate-metabolite-risk-score-predicting-future-weight - 2025-09-15

This 7.5-year prospective controlled exercise intervention study assessed if daily school physical activity (PA), from before to after puberty, improved musculoskeletal traits. There were 63 boys and 34 girls in the intervention group (40 min PA/day), and 26 boys and 17 girls in the control group (60 min PA/week). We measured musculoskeletal traits at the start and end of the study. The overall mu

https://www.lupop.lu.se/article/daily-school-physical-activity-after-puberty-improves-bone-mass-and-musculoskeletal-composite-risk - 2025-09-15

Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential associations between DM, C

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden - 2025-09-15

You can now sign up for participation - in person or online - in Lund Population Day 2020: Healthy Aging. Read more here.

https://www.lupop.lu.se/article/registration-open-lund-population-day-2020 - 2025-09-15

Sports‐related injuries and illnesses in Paralympic sport (SRIIPS) are a concern, but knowledge about the etiology and risk factors is limited. The aim of this study was to describe the annual incidence, type, and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors. New publication in Scandinavian Journal of Medicine & Science in Sports

https://www.lupop.lu.se/article/injuries-and-illnesses-swedish-paralympic-athletes-52-week-prospective-study-incidence-and-risk - 2025-09-15

In addition to a breast density category, temporal changes in breast density have gained attention as a dynamic breast cancer risk marker. This case-control study aimed to investigate a potential change in breast density preceding tumor development and the relationship of this potential change to prognostic pathological tumor variables. New publication in European Journal of Radiology

https://www.lupop.lu.se/article/changes-breast-density-over-serial-mammograms-case-control-study - 2025-09-15

A total of 37 items operationalizing participation were administered via a questionnaire to 364 next of kin of older people in nursing homes. Measurement properties were tested with factor analysis and Rasch model analysis. New publication in PLOS ONE

https://www.lupop.lu.se/article/measuring-next-kins-experience-participation-care-older-people-nursing-homes - 2025-09-15

In Sub-Saharan Africa, being overweight in childhood is rapidly rising while stunting is still remaining at unacceptable levels. A key contributor to this double burden of malnutrition is dietary changes associated with nutrition transition. Although the importance of socio-economic drivers is known, there is limited knowledge about their stratification and relative importance to diet and to diffe

https://www.lupop.lu.se/article/social-stratification-diet-diversity-and-malnutrition-among-preschoolers-survey-addis-ababa-ethiopia - 2025-09-15

Clinical practice improvements based on quality-register data are influenced by multiple factors. Although there is agreement that information from quality registers is valuable for quality improvement, practical ways of organising register use have been notoriously difficult to realise. The present study sought to investigate the mechanisms that lead various clinicians to use quality registers fo

https://www.lupop.lu.se/article/role-professional-logics-quality-register-use-realist-evaluation-0 - 2025-09-15

Sun exposure in combination with skin pigmentation is the main determinant for vitamin D status. Human skin color seems to be adapted and optimized for regional sun ultraviolet (UV) intensity. However, we do not know if fair, UV-sensitive skin is a survival advantage in regions with low UV radiation. New publication in PLOS ONE

https://www.lupop.lu.se/article/women-fair-phenotypes-seem-confer-survival-advantage-low-uv-milieu-nested-matched-case-control-study - 2025-09-15