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Japan has a long history of managing natural hazards due to its geography and geology. Simultaneously, it is known as a country with a railway system that is highly punctual, reliable, and safe. This research uses an exploratory approach to review climate change adaptation and disaster risk reduction practices in the Greater Tokyo Area. Unstructured interviews with various stakeholders and a liter
This paper introduces a three-dimensional approach for analysing brokerage in social networks that has the potential to open new areas of research in Science and Technology Studies (STS). Brokerage is a fundamental concept in social network analysis, where it refers to situations in which actors bridge otherwise disconnected actors. Such brokerage can have both individual consequences and conseque
The purpose of current study is to produce groundwater qanat potential map using frequency ratio (FR) and Shannon's entropy (SE) models in the Moghan watershed, Khorasan Razavi Province, Iran. The qanat is basically a horizontal, interconnected series of underground tunnels that accumulate and deliver groundwater from a mountainous source district, along a water- bearing formation (aquifer), and t
Eye movements do more than gather visual input – they actively contribute to the formation and retrieval of relational memories by linking information across space and time. During retrieval, gaze patterns often reflect memory reactivation well before an explicit response is made, a phenomenon known as the relational eye-movement effect. While this effect appears closely associated with hippocampa
Recent years have seen an uptake in cycling and, with it, an increase in cyclists being involved in crashes. One particularly problematic area is that of urban signalised intersections, which are responsible for a majority of the crashes involving cyclists. One reason is the increased complexity at such locations. The bike box has been hailed as an infrastructure measure to help increase the safet
Transitioning towards a circular economy, where the existing building stock is more efficiently used, would significantly reduce material and energy use, emissions, and waste from the built environment sector. This study focuses on exploring what conditions are needed for circularity by imagining preferable circular futures for a 2035 timeframe and understanding the required actions to achieve the
Cerebral small vessel disease (CSVD) are highly age-related pathologies isualized by neuroimaging. CSVD can be silent lesions but are associated with cognitive decline, dementia, gait disorders, depression and stroke. A growing body of evidence links CSVD to systemic vascular processes, but the pathophysiology is not fully explained. The aim of this thesis is to investigate possible links between
This doctoral thesis explores the phenomenon of choice awareness through an interdisciplinary framework grounded in cognitive semiotics. Combining phenomenological philosophy with empirical investigations, the thesis examines how awareness of choice manifests across different levels of consciousness and within diverse semiotic systems. Papers 1 to 3 present experimental studies using choice manipu
Radionuclide therapy involving 177Lu-labelled somatostatin analogues for the treatment of neuroendocrine tumours isincreasing. While the treatment is currently administered according to a standard protocol, patient-specific treatmentsbased on dosimetry are believed to be beneficial. However, commonly adopted dosimetry procedures are lacking, andlocally developed dosimetry methods are used, which mRadionuclide therapy involving 177Lu-labelled somatostatin analogues for the treatment of neuroendocrine tumours isincreasing. While the treatment is currently administered according to a standard protocol, patient-specific treatmentsbased on dosimetry are believed to be beneficial. However, commonly adopted dosimetry procedures are lacking, andlocally developed dosimetry methods are used, which m
Bland vuxna hjärntumörer utmärker sig glioblastom (GBM) genom sin höga förekomst och allvarliga förlopp, och kännetecknas av snabb tumörtillväxt och sin ogynnsamma prognos. Gabapentin är ett läkemedel som ofta används vid nervsmärta och epilepsi, och har nyligen uppmärksammats för sin möjliga påverkan på samspelet mellan tumör och nervsystem med potentiella konsekvenser för GBMs förlopp. I denna Among adult brain cancers, glioblastoma (GBM) stands out for its frequency and severity, characterized by rapid progression and poor prognosis. Gabapentin, a gabapentinoid widely prescribed for managing neurological conditions such as neuropathic pain and seizures, has been proposed to influence tumor-neural interactions and modulates glioblastoma outcomes. This study used real-world clinical data
This thesis investigates the adaptive reuse of Vagnsverkstaden, a former railway maintenance hall in Malmö’s Lokstallarna. The project explores how this early 20th-century industrial structure can be transformed into a multifunctional civic space, while preserving its material and historical character. Using site analysis, theoretical frameworks, and case study comparisons, the proposal introduces
PURPOSE Childhood, adolescent, and young adult (CAYA) survivors of cancer are at risk of nephrotoxicity. Surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could slow the progression to higher stages of kidney dysfunction. METHODS The International Late Effects of Childhood Cancer Guideline Harmonization Group established a multidisciplinary panel of
Background: Rubber accelerators found in rubber gloves may cause contact allergy and thus allergic contact dermatitis. Objectives: To investigate which doses of tetraethylthiuram disulfide (TETD) elicit allergic contact dermatitis by patch testing and in a repeated occluded application test simulating glove use. Patients and Methods: A multicentre study was conducted. Eight patients with contact a
For many years, questions about the future have been marginalised within the social sciences: asking how we might live in a post-fossil society, or what are the key decisions and events that could take us there, has been seen as outside of the disciplinary scope. In this chapter – which takes as its point of departure the ‘speculative turn’ that is increasingly inspiring a range of works, from for
Critical-sized bone defects remain a significant unmet clinical need, with > 500,000 reconstructive procedures performed annually in the United States and Europe and associated costs exceeding US$3 billion. Autologous bone grafting—the current gold standard—suffers from limited harvest volume and donor-site morbidity, whereas allografts show variable integration and carry immunological and infecti
