This article gives an overview of microstructure imaging of the brain with diffusion MRI and reviews the state of the art. The microstructure-imaging paradigm aims to estimate and map microscopic properties of tissue using a model that links these properties to the voxel scale MR signal. Imaging techniques of this type are just starting to make the transition from the technical research domain to

Context: End-stage kidney disease (ESKD) is characterized by high physical and psychological burden, and therefore, more knowledge about the palliative care provided close to death is needed. Objectives: To describe symptom prevalence, relief, and management during the last week of life, as well as end-of-life communication, in patients with ESKD. Methods: This study was based on data from the Swe

Background: Cardiac Resynchronization Therapy (CRT) is widely used for treating selected heart failure patients, but patients with myocardial scar respond worse to treatment. The Selvester QRS scoring system estimates myocardial scar burden using 12-lead ECG. This study's objective was to investigate the scores correlation to mortality in a CRT population. Methods and results: Data on consecutive

Rationale and Objectives: This study aimed to evaluate the correlation of quantitative measurements with visual grading regression (VGR) and receiver operating characteristics (ROC) analysis in computed tomography (CT) images reconstructed with iterative reconstruction. Materials and Methods: CT scans on a liver phantom were performed on CT scanners from GE, Philips, and Toshiba at three dose leve

Background: Heart function following heart transplantation (HTx) is influenced by numerous factors. It is typically evaluated using transthoracic echocardiography, but reference values are currently unavailable for this context. The primary aim of the present study was to derive echocardiographic reference values for chamber size and function, including cardiac mechanics, in clinically stable HTx

Background and aim: Carotid artery stenosis is one of the major causes of transient ischemic attack (TIA) and acute ischemic stroke (IS), and carotid surgery and stenting are used to reduce the risk of ipsilateral IS. However, the adherence to the recommendation of carotid imaging in clinical practice has not been well studied. We analyzed proportions of carotid imaging and determinants for its no

Veteberoende ansträngningsutlöst anafylaxi är en potentiellt livshotande födoämnesallergi.Omega-5-gliadin är huvudallergenet bakom sensibilisering mot vete.IgE-sensibilisering mot vete i kombination med den samverkande faktorn fysisk ansträngning kan orsaka anafylaxi.Veteberoende ansträngningsutlöst anafylaxi är ett viktigt tillstånd att känna till.Det är viktigt att uppta noggrann anamnes på allaCinnamon rolls triggered anaphylactic reaction. The genesis could be wheat-dependent exercise-induced anaphylaxis Two case reports from our Department of Allergology illustrate the wheat-dependent exercise-induced anaphylaxis (WDEIA), which is a relatively rare, yet potentially fatal form of food allergy. Wheat (Triticum aestivum) is the most commonly grown crop world-wide, and some individuals ca

Context: Lynch syndrome (LS) is a cancer-predisposing syndrome caused by germline mutations in genes involved in DNA mismatch repair (MMR). Patients are at high risk for several types of cancer, but pituitary tumors have not previously been reported.Case: A 51-year-old man with LS (MSH2 mutation) and a history of colon carcinoma presented with severe Cushing disease and a locally aggressive pituit

Heart failure (HF) is the end-stage of all heart disease and arguably constitutes the greatest unmet therapeutic need in cardiovascular medicine today. Classic epidemiological studies have established clinical risk factors for HF, but the cause remains poorly understood in many cases. Biochemical analyses of small case-control series and animal models have described a plethora of molecular charact

Opsoclonus myoclonus syndrome (OMS), often called "dancing eyed syndrome," is a rare neurological condition associated with neuroblastoma in the majority of all childhood cases. Genomic copy number profiles have shown to be of prognostic significance for neuroblastoma patients. The aim of this retrospective multicenter study was to analyze the genomic copy number profiles of tumors from children w

Tillgängliga forskningsresultat om samband mellan radikalisering, terrorism och psykisk ohälsa kan ännu inte användas som underlag för beslut om ändrade rutiner eller behandlingsmetoder i klinisk psykiatrisk verksamhet. De screening- och riskbedömningsverktyg som finns tillgängliga för kliniskt bruk går inte att använda inom psykiatrin utan att psykiatrins roll i det svenska samhäl-let allvarligt There is little evidence supporting the concept of mental illness as a part of, or reason behind radicalization towards violent extremism and terrorism. There is weak evidence that lone gunmen, particularly those involved in school shootings, may suffer from mental illness to a larger degree than the general population, whereas organized terrorist groups such as jihadists and right-wing extremists

Pelvic and paraaortic lymphadenectomy are standard procedures for staging of genital cancers but may also be indicated by other malignancies in the pelvis. The procedures are well suited for minimally invasive surgery and robot assistance may help generalize and standardize the procedures.Step by step surgical techniques for pelvic and paraaortic lymphadenectomy will be described.