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Researchers selecting probands for molecular genetic studies confront a range of sampling issues with modest empirical guidance. In this paper, using cases of major depression (MD), anxiety disorders (AD) alcohol use disorder (AUD), drug use disorder (DUD), bipolar disorder (BD) and schizophrenia (SZ) from a large population cohort of all native Swedes born 1940–2003, we examine the implications o
Differences between men and women in cognitive impairment and neurodegeneration are not yet well understood. Although sex differences in brain structure abnormalities, including white matter hyperintensities (WMH) and grey matter (GM) atrophy, have been associated with cognitive decline in the ageing population, the evidence is limited and inconclusive. Therefore, we explored sex differences in br
The study of rock performance must inevitability be performed on recorded material, since a performance only exists hic et nunc. This brings certain limitations into the analysis, since a recording can’t cover everything that happens on stage. In this paper I will discuss a possible use of intermedial studies and new materialism on the rock performances in focus of my project, to bring forth what
Objective: To describe the clinical and ultrasound characteristics of serous and mucinous cystadenomas in the adnexa. Methods: This was a retrospective international multicenter study. Using the International Ovarian Tumor Analysis (IOTA) database, patients with a histological diagnosis of serous or mucinous cystadenoma who had undergone preoperative ultrasound examination between 1999 and 2016 (I
Kyrkomusikerbristen inom Svenska kyrkan beskrivs ofta som problematisk. Röster höjs för att alternativa studiegångar ska kunna leda till behörighet för tjänst som kyrkomusiker i Svenska kyrkans församlingar, och samfundet har en struktur för validering av utbildning och arbetslivserfarenhet. I denna skrift beskrivs en sådan valideringsprocess. Den ger en mindre smickrande verklighetsbild av Svensk
According to Jan Kandiyai (2020), socialists should not make the republican understanding of freedom as non-domination central to their political theory. He argues that although co-called socialist republicans can successfully criticise the market economy for enabling employers to impose their wills upon workers, they are less successful when considering its structural and impersonal mechanisms. T
The thesis analyzes and explains the current situation for the Russian minority in Estonia. Using Oren Yiftachel’s theoretical framework of Ethnocracy, it examines key documents related to integration, such as the constitution and policy documents, through textual analysis. It briefly covers the integration process from independence in the 1990s to the present. The findings of the study shows that
In may of 2022 a EU law was proposed with the intent of stopping the online spread of CSAM (Child Sexual Abuse Material) by monitoring all online communication in search of child exploitation material. Since then, the proposed law has come under scrutiny due to the suggested surveillance of civilians without any need for criminal suspicion. Today the proposed law is most commonly known as Chat Con
Shelley King and John B. Pierce’s edition of The Romance of the Forest (1791) brings Ann Radcliffe’s (1764–1823) novel to new life. The editors’ introduction is paired with well selected source documents contemporaneous with the influential Gothic romance. My favourite example (not included by King and Pierce) for the Romantic-era writers’ admiration for Radcliffe’s aesthetics is John Keats’s lett
Sepsis remains a major clinical challenge due to the limited efficacy of existing therapies in controlling excessive inflammation. The engineered stapled peptide sHVF18, derived from an evolutionarily conserved thrombin innate fold, binds both lipopolysaccharide (LPS) and the LPS-binding groove of CD14, enabling dual targeting of bacterial components and host immune signaling. To define structural
IntroductionPancreatic cancer has a low survival. The aim of this study was to analyze the role of tumor location on perioperative outcome and survival.MethodData on all patients with resected pancreatic ductal adenocarcinoma (PDAC) identified in the Swedish National Pancreatic and Periampullary Cancer Registry 2010-2020 were included. Tumor locations in the head, body and tail were compared. A mu
BackgroundMonogenic insulin resistance (IR) includes lipodystrophy and disorders of insulin signalling. We sought to assess the effects of interventions in monogenic IR, stratified by genetic aetiology.MethodsSystematic review using PubMed, MEDLINE and Embase (1 January 1987 to 23 June 2021). Studies reporting individual-level effects of pharmacologic and/or surgical interventions in monogenic IR
INTRODUCTION: Ulnar nerve entrapment (UNE) is a common disorder with many associated risk factors. Diabetes mellitus (DM) is an established risk factor, but less is known about metabolic risk factors in individuals without diabetes. Our study aimed to explore the association of body mass index (BMI) with UNE during long-term follow-up.METHOD: The population-based cohort study Malmö Diet and Cancer
INTRODUCTION: Flexible bronchoscopy is regarded as a safe examination and is commonly used in the diagnostic work-up for lung diseases, but is also important in pulmonary research. We aimed to investigate participants' experiences when undergoing bronchoscopy in a research setting.METHODS: Participants were recruited from the Swedish CArdioPulmonary bioImage Study (SCAPIS). A subset from this coho
