The prevalence of cardiometabolic multimorbidity is increasing.

This paper considers the problem of performing mid-ranging control of two closed-loop controlled systems that have internal saturations. The problem originates from previous work in machining with industrial robots, where an external compensation mechanism is used to compensate for position errors. Because of the limited workspace and the considerably higher bandwidth of the compensator, a mid-ran

Solutions of the amines N-methyldiethanolamine (MDEA) and piperazine (PZ) are commonly used for CO2 removal in industrial applications. This is mainly due to the low heat of reaction of MDEA, reducing the heat required for regeneration, and the high reaction rate of PZ, which reduces the size of the absorption tower. However, the effect of PZ on the heat of absorption in a mixture of these two sol

Isothermal microcalorimetry is a label-free assay that allows monitoring of enzymatic and metabolic activities. The technique has strengths, but most instruments have a low throughput, which has limited their use for bioassays. Here, an isothermal microcalorimeter, equipped with a vessel holder similar to a 48-well plate, was used. The increased throughput of this microcalorimeter makes it valuabl

Rheumatoid arthritis (RA) that is negative for anticitrullinated protein antibodies (ACPA) is a subentity of RA, characterized by less severe disease. At the individual level, however, considerable differences in the severity of joint destruction occur. We performed a study on genetic factors underlying the differences in joint destruction in ACPA-negative patients.

According to a standard account of incomparability, two value bearers are incomparable if it is false that there holds a positive value relation between them. Due to the vagueness of the comparative predicates it may also be indeterminate as to which relation that holds - for each relation it is neither true nor false that it holds. John Broome has argued that indeterminacy cannot coexist with inc

The substitution reaction of trans-[Rh(Cl)(CO)(SbPh3)(2)] (1) with tris(2,4-di-tert-butylphenyl)phosphite (2,4-TBPP) to form trans-[Rh(Cl)(CO)(2,4-TBPP)(2)] (4) in two consecutive steps has been investigated by UV-vis stopped-flow spectrophotometry. The experiments were performed in dichloromethane and in ethyl acetate, at 298 K and 268 K respectively for the first reaction step, and for the secon

Objective-To study how Niemann-Pick disease type C1 (NPC1) influences hepatic triacylglycerol (TG) metabolism and to determine whether this is reflected in circulating lipid levels. Methods and Results-In Npc1(-/-) mice, the hepatic cholesterol content is increased but the TG content is decreased. We investigated lipid metabolism in Npc1(-/-) mouse hepatocytes and the association of NPC1 single-nu

In the past years, research on military applications of neuroscience has grown in sophistication. We may expect that future neuroweapons will be advertised as resting on the most objective form of human cognition, leading to greater accuracy in targeting and better compliance with the law than traditional weapons. Are states using weapon systems that draw on neuroscience capable of applying IHL to

High and low tones on Swedish word stems are associated with different classes of suffixes. We tested the electrophysiological effects of high and low stem tones as well as tonally cued and uncued suffixes. Two different tasks were used involving either choosing the suffix-dependent meaning of the words, or pressing a button when the word ended. To determine whether effects were in fact due to ass

OBJECTIVE: To establish the diagnostic sensitivity of and the relationships between autoantibodies to all three Zinc transporter 8 (Zinc transporter 8 autoantibody to either one, two, or all three amino acid variants at position 325, ZnT8A) variants to human leukocyte antigen (HLA)-DQ and to autoantibodies to glutamic acid decarboxylase (GADA), insulinoma-associated protein 2 (IA-2A), and insulin

Neuroendocrine tumors (NETs) represent a heterogeneous group of diseases with varied natural history and prognosis depending upon the organ of origin and grade of aggressiveness. The most widely used biomarker to determine disease burden and monitor response to treatment is chromogranin A (CgA), but it is far from being the optimal predictive and prognostic biomarker in NETs. Biological understand

Cancer runs in families, suggesting a heritable component, but the contribution of environmental factors cannot be neglected. Studies on spousal risk can partly disentangle the environmental contribution but miss shared environmental factors during childhood and adolescence. Here, we examined the familial aggregation of common cancers among 80 281 Swedish-born adoptees, identified from the nationa

Large volcanic eruptions impact significantly on climate and lead to ozone depletion due to injection of particles and gases into the stratosphere where their residence times are long. In this the composition of volcanic aerosol is an important but inadequately studied factor. Samples of volcanically influenced aerosol were collected following the Kasatochi (Alaska), Sarychev (Russia) and also dur

In recent years there have been increasing evidence associating liver disease with hypercoagulability, rather than bleeding. The aim of the study was to evaluate the haemostatic potential in patients with liver disease.

Modulation photoreflectance spectroscopy and Raman spectroscopy have been applied to study the electronic- and band-structure evolution in (Ga,Mn)As epitaxial layers with increasing Mn doping in the range of low Mn content, up to 1.2%. Structural and magnetic properties of the layers were characterized with high-resolution X-ray diffractometry and SQUID magnetometery,respectively. The revealed res

Pebbles with sizes of centimeters to decimeters are needed in order to form kilometer-sized planetesimals, which in turn are needed for planet formation to proceed. The well-studied mechanism of coagulation is efficient only up to millimeter-sized dust grains. In this proceeding a numerical model of ice condensation as a complementary growth mechanism in turbulent protoplanetary discs is discussed

Single-carrier frequency division multiple access (SC-FDMA) is considered as a promising technique that is adopted in the uplink for the upcoming 3GPP long term evolution (LTE). This is because it keeps most of the advantages of OFDMA in addition to low peak to average power ratio (PAPR). Designing diversity achieving schemes for SC-FDMA is a challenging task. The code should not affect the PAPR a

The concept of storytelling as a description (or prescription) regarding jazz music is a very old and very common trope in jazz discourses. Arguably, however, this usage seems to have been taken for granted, and has not been sufficiently investigated and problematized. One of several important aspects of the concept of storytelling as applied to jazz music has to do with the music’s semantic poten