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The cerebral hemorrhage-producing cystatin C variant (L68Q) in extracellular fluids

A variant of the normal extracellular cysteine protease inhibitor cystatin C (L68Q-cystatin C), is the amyloid precursor in hereditary cystatin C amyloid angiopathy (HCCAA). It has been suggested that the mutation causes cellular entrapment of L68Q-cystatin C in vivo and that the variant protein is not secreted to extracellular fluids. In order to test this hypothesis, we used matrix-assisted lase

Behaviour of fracture process zones in concrete influenced by simultaneously applied normal and shear displacements

The thesis deals with the determination of the post peak behaviour of concrete in pure tension, and combined tension (compression) and shear. A test arrangement has been developed in order to determine the post peak behaviour of concrete expressed as stress - displacement curves. The theoretical basis of the thesis is in accordance with the "Fictitious Crack Model" which is a model based on the s

An X-ray scanner for wire chambers

The techniques to measure the position of sense wires and field wires, the gas gain and the gas flow rate inside wire chambers using a collimated and filtered X-ray beam are reported. Specific examples are given using barrel modules of the Transition Radiation Tracker of the ATLAS experiment. (C) 2003 Elsevier B.V. All rights reserved.

Biological reduction of hexavalent chromium - A field study

When ferrochromium is produced at Vargon Alloys AB (Vargon, Sweden), an offgas dust is generated as a byproduct. A leachate that contains hexavalent chromium (Cr6+) is formed when rainwater percolates through the dust deposit. In this study, Cr6+ in the leachate was reduced to trivalent chromium (Cr3+) by biological treatment in a biofilm process operated under anaerobic conditions. The reactor vo

Levator co-activation is a significant confounder of pelvic organ descent on Valsalva maneuver.

Objective A Valsalva maneuver is used clinically and on imaging in order to determine female pelvic organ prolapse. We have examined the Potential confounding effect of levator co-activation at the time of a Valsalva maneuver and the impact of repetition with biofeedback instruction. Methods Fifty nulliparous women at 36-38 weeks' gestation received 3D/4D translabial ultrasound investigation in th

Hand muscle pathology after long-term vibration exposure.

The morphology of the abductor pollicis brevis muscle was studied in 20 patients suffering from hand-arm vibration syndrome. The main morphological changes observed were centrally located myonuclei and fibre type grouping (found in all 20 muscle biopsies), angulated muscle fibres (found in 19 biopsies), ring fibres and regenerating fibres (found in 18 biopsies) and fibrosis (found in 17 biopsies).

Performance of a sisal fibre fixed-bed anaerobic digester for biogas production from sisal pulp waste

A single stage anaerobic digester employing a sisal fibre waste fixed bed was studied for biogas production from sisal pulp waste. The fibre was colonized by microorganisms involved in biogas production. The sisal pulp waste to be digested was fed from the top and was sprinkled intermittently with recirculating leachate from the material. Organic loading rates of 0.1-10 kg volatile solids (VS) m-3

Behaviour of male pine sawflies, Neodiprion sertifer , released downwind from pheromone sources

This study investigated the behaviour of male European pine sawflies, Neodiprion sertifer Geoffroy (Hym., Diprionidae), that were released and observed downwind from pheromone traps baited with 100 mu g of the sex pheromone, (2S,3S,7S)-3,7-dimethyl-2-pentadecyl acetate. Releases were done at three distances; either at 5 m from one trap, or at 50 or 200 m from five traps, placed in a line perpendic

Chemometric exploration of an amperometric biosensor array for fast determination of wastewater quality

Four wastewater samples of different treatment qualities; untreated, alarm, alert and normal, from a Swedish chen-ti-thermo-mechanical pulp mill and pure water were investigated using an amperometric bioelectronic tongue in a batch cell. The aim was to explore enzymatically modified screen-printed amperometric sensors for the discrimination of wastewater quality and to counteract the inherent drif

Delayed g9/2 Alignment in the N=Z Nucleus 72Kr

The structure of Kr-72 has been investigated at GASP through the Ca-40(Ca-40,2 alpha) reaction at a beam energy of 160 MeV using the 4 pi ISIS Si-ball for reaction channel selection. The level scheme has been extended up to an excitation energy of approximate to 8.5 MeV. The spins and parities of the observed levels are assigned tentatively. The observed band shows the predicted change from oblate

Product-service systems for office furniture: barriers and opportunities on the European market

The environmental problems associated with office furniture consumption call for a more efficient use of office furniture that can decrease emissions and,volume of waste. The author discusses the opportunities and barriers for the implementation of a PSS for office furniture. In addition, the paper identifies possibilities to overcome these barriers. The article is based on interviews with Europea

Who the Hell Is in It?

Discussion about Director/Actor/Film Historian Peter Bogdanovich with regard to his book Who the hell is it? (In Swedish)

Resonant inelastic X-ray scattering at the Be 1s edge in BeO

We present the resonant inelastic X-ray scattering (RIXS) spectra of BeO at the Be 1s photoabsorption edge. The RIXS spectra excited in the vicinity of the core exciton resonance show two principal features: the scattering on a valence exciton (which at higher excitation energies verges into the characteristic K alpha emission), and a remarkably strong energy loss side-band to the elastic scatteri

Sex pheromone for monitoring flight periods and population densities of the pine sawfly, Diprion jingyuanensis Xiao et Zhang (Hym., Diprionidae)

The pine sawfly, Diprion jingyuanensis Xiao et Zhang, is a serious pest of Chinese pine (Pinus tabulaeformis Carr.) in the northern parts of China. The general biology of this recently described sawfly species is little known and in the present study we used a synthetic pheromone to monitor its flight period and to evaluate the possibility to use pheromone traps as a tool for estimating and predic

Solvent extraction of silver for pollution control of photographic fixing solutions

Silver recovery from photographic fixing solutions is investigated by applying solvent extraction techniques. Amines were shown to be the most promising extractants and quaternary ammonium chlorides selected for further studies because of high distribution coefficients and low pH-sensitivity. The distribution coefficient for silver from a 0.5 M ammonium thiosulphate solution increases from 2.3 to

Traces of copper ions deplete glutathione in human hepatoma cell cultures with low cysteine content

Background: Cell death induced by intracellutar glutathione depletion has been reported to be dependent on the presence of trace amounts of extracellular copper ions. Since little is known about the relationship between glutathione depletion and copper homeostasis, we have in the present study further investigated the role of low amounts of copper ions in glutathione depletion. Methods: Glutathion

Light chain shuffling of a high affinity antibody results in a drift in epitope recognition

Human polyclonal and monoclonal antibodies against pathogens and toxins are potentially useful in the treatment of various diseases. A number of human monoclonal antibodies with protective capacity in vitro have been established by conventional hybridoma technology. However, with the development of phage-display technology, the possibility of specifically tailoring antigen-binding properties has i