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Improved survival in several cancers with use of H1-antihistamines desloratadine and loratadine

Background: We have previously shown an association with substantially improved survival in breast cancer and melanoma for desloratadine and loratadine users, and set out to find whether an improved survival can be seen in tumors with and without a known response to immune checkpoint therapy, such as anti-CTLA-4 or anti-PD-1. Methods: We investigated survival and use of six common H1-antihistamine

An agenda for sustainability transitions research : State of the art and future directions

Research on sustainability transitions has expanded rapidly in the last ten years, diversified in terms of topics and geographical applications, and deepened with respect to theories and methods. This article provides an extensive review and an updated research agenda for the field, classified into nine main themes: understanding transitions; power, agency and politics; governing transitions; civi

Spatial and socio-economic analysis of public transport systems in large cities : A case study for Belo Horizonte, Brazil

The main goal of this article is to evaluate the relationship between the spatial distribution of the population of the city of Belo Horizonte, one of the largest cities in South America, and its public transport network, seeking to ascertain whether the current bus network is able to meet the needs of the population. The methodology was based on data processing and vector information from differe

HÉR! Of curation in the act

This presentation looks at the curatorial practice within my PhD project titled HÉR! An explora- tion of artistic agency. The project is designed to look at situated actions through a row of case studies that link to my role as performer, composer and curator within contemporary music and sound art. The curation has spanned various processes, such as the concert event, the act of stu- dio recordin

Benefits of protected areas for nonbreeding waterbirds adjusting their distributions under climate warming

Climate warming is driving changes in species distributions and community composition. Many species have a so-called climatic debt, that is, shifts in range lag behind shifts in temperature isoclines. Inside protected areas (PAs), community changes in response to climate warming can be facilitated by greater colonization rates by warm-dwelling species, but also mitigated by lowering extirpation ra

Toward nonparametric diffusion-T1 characterization of crossing fibers in the human brain

Purpose: To estimate (Formula presented.) for each distinct fiber population within voxels containing multiple brain tissue types. Methods: A diffusion- (Formula presented.) correlation experiment was carried out in an in vivo human brain using tensor-valued diffusion encoding and multiple repetition times. The acquired data were inverted using a Monte Carlo algorithm that retrieves nonparametric

Associations Between Systolic Interarm Differences in Blood Pressure and Cardiovascular Disease Outcomes and Mortality : Individual Participant Data Meta-Analysis, Development and Validation of a Prognostic Algorithm: The INTERPRESS-IPD Collaboration

Systolic interarm differences in blood pressure have been associated with all-cause mortality and cardiovascular disease. We undertook individual participant data meta-analyses to (1) quantify independent associations of systolic interarm difference with mortality and cardiovascular events; (2) develop and validate prognostic models incorporating interarm difference, and (3) determine whether inte

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Criminology is not just focused on explaining the etiological factors behind crime commission; ultimately the goal is to find and empirically assess policies to control it. A criminology of the State is no different. Over the course of the past two decades, a growing number of scholars of State crime have devoted attention to and research on the issues of controls, yet, there have been relatively

Att leva med bakterier : Möjligheter till ett levbart immunitärt liv

Det uppskattas att år 2050 kommer tio miljoner människor att dö av infektionersom inte kan behandlas på grund av att bakterier blivit resistenta ochdärmed gjort antibiotika ineffektiv. Denna typ av dystopier är en form avresor både bakåt och framåt i tiden, och där samhället beskrivs som någotannat än vad vi är vana vid. Tanken om en framtid utan antibiotika – enså kallad postantibiotisk era – går

Kv1.3 Channel, a Targetable Piece in the Complex Jigsaw Puzzle of Vascular Calcification?

In parallel with an unprecedented progress in vascular and stem cell biology during the past two decades, our understanding of vascular calcification has evolved from being perceived as a harmless, passive deposition of minerals to what we now consider a highly regulated, cell-mediated process that is strongly associated with chronic kidney disease (CKD) and confers increased risk for incident car

Co-production of urban knowledge: Context approach for effective and efficient governance of cities

Effective and efficient governance is driven by policies that prevail in urban contexts. Policies are usually the result of knowledge co-production, but the efficacy of the process of translating knowledge into policy is still not well defined in the Kenyan context. One example of this is the city of Kisumu, which has been the focus of knowledge co-production by researchers from Kisumu and Gothenb

The association of mode of location activity and mobility with acute coronary syndrome : a nationwide ecological study

Background: We aimed to study the effect of social containment mandates on ACS presentation during COVID-19 pandemic using location activity and mobility data from mobile phone map services. Methods: We conducted a cross-sectional study using data from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) including all ACS presentations during the pandemic until 7 May 2020. Using a cou

Vestibular rehabilitation for persons with stroke and concomitant dizziness - A pilot study

Background: Dizziness is common among patients with first time stroke. It affects self-perceived health and is a risk factor for falls. Vestibular rehabilitation (VR) is effective for treating dizziness among various conditions, but the effect of dizziness with origin in the central nervous system is poorly studied. This pilot study of a randomized controlled trial aimed at investigating a vestibu

Wavelength frame multiplication for reflectometry at long-pulse neutron sources

The European Spallation Source (ESS), which is under construction in Lund (Sweden), will be the next leading neutron facility with an unprecedented brilliance and novel long-pulse time structure. A long-pulse source not only provides a high time-average flux but also opens the possibility to tune the resolution by using pulse shaping choppers. Thus, an instrument can readily be operated in either