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Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive soft tissue sarcoma. In the majority of cases, there is overexpression of MUC4, and most cases show EWSR1-CREB3L1 gene fusions. A subset of SEF displays composite histologic features of SEF and low-grade fibromyxoid sarcoma (LGFMS). These "hybrid" tumors are more likely to harbor the FUS-CREB3L2 fusion, which is also seen in most LGFMS. We

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Abstract: Reports and studies repeatedly indicate that foreign languages other than English are facing major challenges in European educational systems (European Commission, 2012). In Sweden, pupils’ motivation to learn a second foreign language (SFL) is reported to be low while motivation to learn English is high (Eurobarometer 2012, Tholin & Lindqvist 2009). While there are plenty of studiesAbstract: Reports and studies repeatedly indicate that foreign languages other than English are facing major challengesin European educational systems (European Commission, 2012). In Sweden, pupils’ motivation to learn a secondforeign language (SFL) is reported to be low while motivation to learn English is high (Eurobarometer 2012, Tholin& Lindqvist 2009). While there are plenty of studies st

Electric quadrupole matrix elements, Mp, for the Jπ=2+→0+, ΔT=0, T=1 transitions across the A=46 isobaric multiplet 46Cr-46V-46Ti have been measured at GSI with the FRS-LYCCA-AGATA setup. This allows direct insight into the isospin purity of the states of interest by testing the linearity of Mp with respect to Tz. Pairs of nuclei in the T=1 triplet were studied using identical reaction mechanisms

Mobile and wireless data are in increasing demand worldwide. New trends such as the Internet of Things paradigm and the Smart City paradigm describe scenarios comprising thousands of devices all exchanging information amongst themselves wirelessly --- or through the WAN to another device, possibly connected to another WLAN. Operators and radio engineers are faced with the problem of designing effi

BackgroundThe majority of people with dementia prefer to live independently and safely in their own home cared for by their family members. Much effort has been invested in the development of technology, such as sensor‐based networks. Many challenges remain, in particular gaining more knowledge about their experiences and perceived benefits. This study aimed to explore experiences, needs and benef

Figurative language repositories typically encompass expressions that are coded manually in formal content analyses. This chapter proposes to discuss a number of theoretical and methodological issues related to mereology – the study of parts, wholes, and their relation – that are crucial for coding part–whole figurative expressions. This contribution draws the attention to the importance of: disti

Neuromuscular disorders are often caused by heterogeneous mutations in large, structurally complex genes. Targeting compensatory modifier genes could be beneficial to improve disease phenotypes. Here we report a mutation-independent strategy to upregulate the expression of a disease-modifying gene associated with congenital muscular dystrophy type 1A (MDC1A) using the CRISPR activation system in m

Circulating microRNAs (miRNAs) are being considered as non-invasive biomarkers for disease progression and clinical trials. Congenital muscular dystrophy with deficiency of laminin α2 chain (LAMA2-CMD) is a very severe form of muscular dystrophy, for which no treatment is available. In order to identify LAMA2-CMD biomarkers we have profiled miRNAs in urine from the dy2J /dy2J mouse model of LAMA2-

Fossilized eyes permit inferences of the visual capacity of extinct arthropods1–3. However, structural and/or chemical modifications as a result of taphonomic and diagenetic processes can alter the original features, thereby necessitating comparisons with modern species. Here we report the detailed molecular composition and microanatomy of the eyes of 54-million-year-old crane-flies, which togethe

This paper estimates the effect of female economic empowerment on domestic violence. I use individual level data from high-quality Swedish administrative registers on women's earnings and hospital visits relating to assault. With this third-party reported violence measure, I overcome the issue of selective under-reporting of violence. I proxy female economic empowerment with a measure of women's p

Peel testing is used to study adhesive fracture in packaging material laminates. The focus is on improved understanding of the mechanisms that provide a laminate's adhesive properties, as measured by standard macroscopic tests. Using a specially-designed peel test load rig, peel tests are performed in-situ in a laboratory X-ray tomograph. The peel test results are analyzed using a combination of tPeel testing is used to study adhesive fracture in packaging material laminates. The focus is on improved understanding of the mechanisms that provide a laminate's adhesive properties, as measured by standard macroscopic tests. Using a specially-designed peel test load rig, peel tests are performed in-situ in a laboratory X-ray tomograph. The peel test results are analyzed using a combination of t

We study a scenario where a monitor is interested in the freshest possible update from a remote sensor. The monitor also seeks to minimize the number of updates that exceed a certain freshness threshold, beyond which, the information is deemed to be too old. Previous work has presented results for First Come First Served (FCFS) systems. However, it has been shown that Last Come First Served (LCFS)We study a scenario where a monitor is interested in the freshest possible update from a remote sensor. The monitor also seeks to minimize the number of updates that exceed a certain freshness threshold, beyond which, the information is deemed to be too old. Previous work has presented results for First Come First Served (FCFS) systems. However, it has been shown that Last Come First Served (LCFS)

Plant-based diets are the main source of nutrients for vegetarians worldwide and for low-income inhabitants of developing countries, such as in rural areas of Bolivia. These diets may contain high levels of mineral inhibitors such as phytate that impairs mineral absorption in the human gut. Low intake of minerals in combination with mineral inhibitors is a critical factor leading to mineral defici

In this paper we study reliability, timeliness and load reduction in an hybrid Mobile Edge Computing (MEC)/Cloud game streaming infrastructure. In our scenario, a user plays a game streamed by the producer to their handheld device – or User Equipment (UE). The UE communicates user actions to the edge/cloud via the mobile communication infrastructure; the object is to retrieve the latest game statuIn this paper we study reliability, timeliness and load reduction in an hybrid Mobile Edge Computing (MEC)/Cloud game streaming infrastructure. In our scenario, a user plays a game streamed by the producer to their handheld device -- or User Equipment (UE). The UE communicates user actions to the edge/cloud via the mobile communication infrastructure; the object is to retrieve the latest game stat