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Random effects during training : Implications for deep learning-based medical image segmentation

Background: A single learning algorithm can produce deep learning-based image segmentation models that vary in performance purely due to random effects during training. This study assessed the effect of these random performance fluctuations on the reliability of standard methods of comparing segmentation models. Methods: The influence of random effects during training was assessed by running a sin

Punishment Moralism

In this paper, I try to reconcile the vulgar (normative) definition of punishment with the positivistic (purely descriptive) definition that separates the ethics of punishment from its definition—punishment positivism. I will argue that although the vulgar definition has critical issues, this does not mean that we should stop using normative concepts in the definition of punishment. I will attempt

Experimental and kinetic modelling study on the laminar burning velocities of ultra-lean n-heptane flames at atmospheric pressure

Ultra-lean combustion is a promising strategy for enhancing engine efficiency and reducing pollutant emissions. In the present study, laminar burning velocity, SL, of n-heptane, a key gasoline surrogate component, was measured at 298 K and 1 atm using the heat flux method. The experimental conditions cover ultra-lean conditions with an equivalence ratio as low as 0.5 that have never been reported

Probing the strength of radial migration via churning by using metal-rich red giant stars from APOGEE

Making use of the APOGEE DR17 catalogue with high quality data for 143 509 red giant branch stars we explore the strength of different mechanisms that causes a star to radially migrate in the Milky Way stellar disc. At any position in the disc we find stars that are more metal-rich than the local interstellar medium. This is surprising and normally attributed to the migration of these stars after

Dynamics of Aedes aegypti mating behaviour

The use of pheromones, while common, remains underexplored in mosquito research. Understanding Aedes aegypti's mating behaviour and pheromones is crucial for expanding knowledge and advancing vector control strategies. Unlike other species, Aedes mosquitoes have adaptable mating behaviour, complicating the study of their communication mechanisms. Current literature on Aedes communication is sparse

Statistical Combination of ATLAS Run 2 Searches for Charginos and Neutralinos at the LHC

Statistical combinations of searches for charginos and neutralinos using various decay channels are performed using 139 fb^{-1} of pp collision data at sqrt[s]=13 TeV with the ATLAS detector at the Large Hadron Collider. Searches targeting pure-wino chargino pair production, pure-wino chargino-neutralino production, or Higgsino production decaying via standard model W, Z, or h bosons are combined

arkitekten: Skolgårdarna är en nyckel till hållbar framtid

En grön skolgård med många olika träd, buskar och blommor ger stora pedagogiska möjligheter, stärker den biologiska mångfalden, motverkar klimatförändringar och bidrar till barns hälsa och utveckling. Ändå är det idag få kommuner i landet som aktivt satsar på att utveckla skolgårdar med dessa kvaliteter. Finansiering av gröna skolgårdsprojekt behöver öka som en grund för en hållbar framtid!

International Human Rights Commitments to Protect Victims of Domestic Violence: Refugee recognition as the first step for an integrated approach under EU law in Case C-621/21, Intervyuirasht organ na DAB pri MS (Women victims of domestic violence)

The judgment by the Grand Chamber of the Court of in Case C-621/21 Intervyuirasht organ na DAB pri MS case has already attracted significant attention for the finding of the Court that women victims of domesticviolence can be considered as members of particular social group for the purposes of recognition of refugee status. This case note presents the the facts of the case and analyses reasoning o

Tear secretion is preserved while the area of meibomian glands is reduced in patients with prosthetic eyes, contributing to the symptoms of dry eye

Background/aims It is unclear whether a reduction in tear secretion contributes to the discomfort experienced by those with prosthetic eyes. Tear secretion has hitherto only been measured with the Schirmer test which may be affected by the pooling of tears behind the prosthesis. In this study, direct imaging of the lacrimal gland has been performed to measure tear secretion in anophthalmic sockets

Individually tailored exercise in patients with postural orthostatic tachycardia syndrome related to post-COVID-19 condition - a feasibility study

Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical e

The use of starch microspheres and nanoparticles in pharmaceutical applications

Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presen

The Impact of Annealing Methods on the Encapsulating Structure and Storage-Stability of Freeze-Dried Pellets of Probiotic Bacteria

Objective: This paper investigates the critical role of material thickness in freeze-dried pellets for enhancing the storage stability of encapsulated bacteria. Freeze dried material of varying thicknesses obtained from different annealing durations is quantified using Scanning Electron Microscopy (SEM) and X-ray microtomography (μCT), the material thickness is then correlated to the storage stabi