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Comparing Treatment Outcomes of Eligible Patients Consenting to or Declining Randomization in a Randomized Clinical Trial A Secondary Analysis of the FISH Trial on Humeral Shaft Fractures

Background: The Finnish Shaft of the Humerus (FISH) trial compared open reduction and internal plate fixation (ORIF) with functional bracing in adult patients with displaced, closed humeral shaft fractures. Here, we compare the results of the patients in the randomized clinical trial (RCT [the randomized cohort]) with those of the cohort of patients who were also eligible but declined randomizatio

Smooth muscle-specific deletion of cellular communication network factor 2 causes severe aorta malformation and atherosclerosis

AIMS: Cellular communication network factor 2 (CCN2) is a matricellular protein implicated in fibrotic diseases, with ongoing clinical trials evaluating anti-CCN2-based therapies. By uncovering CCN2 as abundantly expressed in non-diseased artery tissue, this study aimed to investigate the hypothesis that CCN2 plays a pivotal role in maintaining smooth muscle cell (SMC) phenotype and protection aga

Interfaces with syntax in language acquisition

We introduce empirical work on Romance language acquisition withrespect to the interfaces of syntax with other modules of grammar (internal interfaces)and other domains of cognition (external interfaces). We do so by choosing specificphenomena within the following interfaces: syntax-morphology, syntax-semanticsand syntax-pragmatics. In the domain of syntax-morphology we focus on grammaticalgender,

Sociodemographic differences in the response to changes in COVID-19 testing guidelines

During the coronavirus disease 2019 (COVID-19) pandemic, Sweden emphasized voluntary guidelines over mandates. We exploited a rapid change and reversal of the Public Health Agency of Sweden's COVID-19 testing guidelines for vaccinated and recently infected individuals as a quasi-experiment to examine sociodemographic differences in the response to changes in pandemic guidelines. We analyzed daily

High leptin levels in blood are associated with chronic widespread pain in rheumatoid arthritis

Background: High body mass index (BMI) has been shown to have an association with chronic widespread pain (CWP), both in Rheumatoid arthritis (RA) and in other pain conditions such as fibromyalgia. Research on the adipose tissue and it’s adipokines, for example the well described leptin, is emerging. The objective of this study was to determine if there is an association between leptin levels in b

Identification of sentinel lymph node macrometastasis in breast cancer by deep learning based on clinicopathological characteristics

The axillary lymph node status remains an important prognostic factor in breast cancer, and nodal staging using sentinel lymph node biopsy (SLNB) is routine. Randomized clinical trials provide evidence supporting de-escalation of axillary surgery and omission of SLNB in patients at low risk. However, identifying sentinel lymph node macrometastases (macro-SLNMs) is crucial for planning treatment ta

Evolution of Home Mechanical Ventilation in Sweden Over 27 Years : Changing Trends in Incidence, Prevalence, and Patient Characteristics - The Population-Based the Course of Disease in Patients Reported to the Swedish CPAP Oxygen and Ventilator Registry (DISCOVERY) Study

Background: Home mechanical ventilation (HMV), noninvasive ventilation and invasive ventilation outside a hospital setting, is a key treatment to improve outcomes in chronic hypoventilation. Research Question: What are the temporal trends observed over 27 years in Sweden regarding the incidence, prevalence, diagnostic spectrum, and patient characteristics associated with HMV? Study Design and Meth

Jämställdhet i barnavårdsutredningar. Socialsekreterares beskrivningar av flickor och pojkar

Gender norms seem to affect social workers' evaluation of children in childcare investigations in Sweden. This essay aimed to determine whether social workers at a Swedish social service center write differently about boys and girls in child care investigation documents based on the children's gender. The sample consisted of nine randomized investigation documents on four boys and five gir

Socialarbetares syn på prostitution i Sverige och Nederländerna - En kvalitativ intervjustudie

In 1999, Sweden became the first country in the world to criminalize the purchase of sex rather than the selling of it. During this time, the Netherlands revoked its ban on brothels, which made prostitution legal but partly regulated by the government. The purpose of this study has been to investigate social workers' views on prostitution in Sweden and the Netherlands. The study was conducted

Barnets deltagande i mål om umgängesbegränsningar- En kvalitativ dokumentstudie av domstolsprotokoll

Children who are placed in foster care because of neglect or abuse have the right to maintain the relationship with their parents, as per the Swedish LVU law, though this is more often than not a complex feat to achieve. The Convention on the Rights of the Child states that children who are capable of forming their views shall be given the right to express those views freely in all matters affecti

Air temperature and precipitation constraining the modelled wetland methane emissions in a boreal region in northern Europe

Wetland methane responses to temperature and precipitation are studied in a boreal wetland-rich region in northern Europe using ecosystem process models. Six ecosystem models (JSBACH-HIMMELI, LPX-Bern, LPJ-GUESS, JULES, CLM4.5, and CLM5) are compared to multi-model means of ecosystem models and atmospheric inversions from the Global Carbon Project and upscaled eddy covariance flux results for thei

Enhancing the Prediction of Lymph Node Metastasis in Early Breast Cancer Using Deep Learning on Routine Full-Breast Mammograms

Background: With a trend toward de-escalation of axillary surgery in breast cancer, prediction models incorporating imaging modalities can help reassess the need for surgical axillary staging. Although mammography is routinely performed for breast cancer imaging, its potential in nodal staging remains underutilized. This study aims to employ advancements in deep learning (DL) to comprehensively ev

Pollination Across the Diel Cycle : A Global Meta-Analysis

The daily transition between day and night, known as the diel cycle, is characterised by significant shifts in environmental conditions and biological activity, both of which can affect crucial ecosystem functions like pollination. Despite over six decades of research into whether pollination varies between day and night, consensus remains elusive. We compiled the evidence of diel pollination from

Envisioning post-growth marketing : A dystopian-optimist’s guide

This article introduces a mode of thought called dystopian optimism in response to the question of how critical marketing can be made more optimistic. Dystopian optimism counters both the utopian-optimistic belief that the climate crisis can be solved from within the current growth-capitalist system, and the dystopian pessimism of terminal marketing. We propose degrowth as a means to revitalise cr

Platser för barn är platser för alla- eller? En barndomssociologisk intervjustudie om barns delaktighet i stadsplaneringsfrågor

Syftet med denna uppsats är att undersöka hur olika aktörer inom kommun och ideell organisation arbetar med barns delaktighet i stadsplanering och stadsutvecklingsfrågor. Vidare syftar studien till att undersöka hur och på vilka sätt föreställningar om barn, barndom och ålder blir synliga i praktiken och hur det påverkar barns möjlighet att involveras. Föreliggande uppsats är en kvalitativ interv

En kritisk diskursanalys av svenska mediers konstruktioner av kvinnliga förövare

The study examined how female perpetrators are constructed in Swedish media, focusing on articles published in national newspapers. The study analysed 18 articles from four major Swedish newspapers, Svenska Dagbladet, Dagens Nyheter, Aftonbladet, and Expressen, published within the last ten years. Using Fairclough’s critical discourse analysis, informed by feminist criminology, the study identifie

"Sluta skicka falska rapporter för att behålla mina barn som gisslan" - Tematisk analys av inlägg om socialtjänsten på TikTok

This study aims to analyze the representation of social services on TikTok. The representations included experiences and opinions about Swedish social services and how TikTok is used to reach out with descriptions of the social services. The purpose of this study is also to analyse how users' way of presenting themselves can be interpreted from a gender perspective. In this study, we used them