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Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes

Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volu

Solute transfer in on-line analytical flow-through dialyzers

Mass transfer in infinite parallel-plate dialyzers with co-flow between sample and detector streams is discussed for three different theoretical models. Analytical solutions with coupled diffusion and membrane transfer equations were obtained for plug flow in both channels. The finite-difference approximation method was used to obtain numerical solutions for a laminar-flow regime. Results obtained

On Simultaneous H2-Optimization of Several Performance Bounds

Simultaneous optimisation of several criteria is an important and interesting subject. Even the standard H2-case is non-trivial. The problem is here treated for the general MIMO case for two conflicting objectives (the results directly generalise to several performance measures). A seminorm D2 is introduced to describe the situation. The state-space solution technique in [Khargonekar and Rotea, 19

Struggling to Make Ends Meet : Lone Mothers and Intergenerational Support in Sweden

Economic divisions have deepened in Sweden in recent years, and lone mothers are one group where the poverty rate has increased most (Salonen 2014). At the same time, di erences between the situations of lone mothers have also increased (Lundqvist 2014). As a consequence, intergenerational support from grandparents in terms of care and nancial transfers are important (see also Halleröd 2008). Thi

Clonal Hematopoiesis and risk of atherosclerotic cardiovascular disease

BACKGROUND Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the presence of an expanded somatic blood-cell clone in persons without other hematologic abnormalities, is common among older persons and is associated with an increased risk of hematologic cancer. We previously found preliminary evidence for an association between CHIP and atherosclerotic cardiovascular diseas

Poor blood pressure control in adults with repaired coarctation of the aorta and hypertension : a register-based study of associated factors

Background: Arterial hypertension is common in adults with repaired coarctation of the aorta, and is associated with several severe complications. Aims: This study aimed to investigate the prevalence of poorly controlled (⩾140/90 mmHg) blood pressure among patients with diagnosed hypertension and to identify associated factors. Methods: In the national register for CHD, adults with repaired coarct

No independent association between pulse wave velocity and dementia : a population-based, prospective study

OBJECTIVE:: Carotid–femoral pulse wave velocity (CFPWV), a marker of aortic stiffness, has been associated with cognitive test results and markers of cerebral small vessel disease, but its association with dementia has not been studied in detail. Our aim was to assess the association of CFPWV with prevalent and incident dementia in a large population-based study. METHODS:: In total, CFPWV was meas

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Six exposures to 95 % CO2 for one minute were made in four pigs. Following onset of CO2-inhalation muscle jerks were observed after a latency of about 15 s. At this time the EEG showed a slow wave pattern typical of general anaesthesia. The short latency muscle jerks were by all probability no emotional stress reactions, but instead the motoric manifestation of a release phenomenon. Therefore, it

Assessment of dermal uptake of diphenylmethane-4,4′-diisocyanate using tape stripping and biological monitoring

Background: Very little is known about the dermal uptake of isocyanates, and dermal exposure to isocyanates has been discussed as a factor involved in the induction of respiratory diseases. Objectives: To investigate the dermal uptake of diphenylmethane-4,4’-diisocyanate (4,4’-MDI). Materials & Methods: Four volunteers were dermally exposed to 10, 25, 49 and 50 mg 4,4’-MDI, respectively, for e

Atrial fibrillation in immigrant groups : a cohort study of all adults 45 years of age and older in Sweden

To study the association between country of birth and incident atrial fibrillation (AF) in several immigrant groups in Sweden. The study population included all adults (n = 3,226,752) aged 45 years and older in Sweden. AF was defined as having at least one registered diagnosis of AF in the National Patient Register. The incidence of AF in different immigrant groups, using Swedish-born as referents

FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population

Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient

Measuring personal recovery – psychometric properties of the Swedish Questionnaire about the Process of Recovery (QPR-Swe)

Background: Personal recovery, defined as an individual process towards meaning, is an important target within mental health services. Measuring recovery hence requires reliable and valid measures. The Process of Recovery Questionnaire (QPR) was developed for that purpose. Aims: The aim was to develop a Swedish version of the QPR (QPR-Swe) and explore its psychometric properties in terms of factor

Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma

18F-Fluorodeoxyglucose (FDG)–positron emission tomography (PET) and diffusion-weighted magnetic resonance imaging with background signal suppression (DWIBS) are 2 powerful functional imaging modalities in the evaluation of malignant plasma cell (PC) disease multiple myeloma (MM). Preliminary observations have suggested that MM patients with extensive disease according to DWIBS may be reported as

Comparison between Individually and Group-Based Insulin Pump Initiation by Time-Driven Activity-Based Costing

Background: Depending on available resources, competencies, and pedagogic preference, initiation of insulin pump therapy can be performed on either an individual or a group basis. Here we compared the two models with respect to resources used. Methods: Time-driven activity-based costing (TDABC) was used to compare initiating insulin pump treatment in groups (GT) to individual treatment (IT). Activ

Global Decent Work through improved industrial relations - hurdles and hope in a global labour market

The globalized and regionalized labour market has brought about significant scrutiny on how to organize not only labour regulations and legal provisions, but also industrial relations for the development, enforcement and monitoring of working life provisions and agreements. There has been an outspoken need to understand the recent situation and to structure a theory of maintaining established regi