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Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc

The incidence of parameningeal infection (PI) is increasing in the context of therapy-induced immunosuppression. PI often presents with atypical symptoms, leading to delayed diagnosis and intervention, and can result in severe neurological sequelae. However, current understanding of PI remains limited due to a lack of basic research on host-pathogen interactions. Here, we first established a trans

I artikeln analyseras förfarandereglerna i den svenska tilläggsskattelagstiftningen och deras förenlighet med unionsrätten och Europakonventionen. Fokus ligger på aspekter kopplade till rapportering, sanktionsavgifter och potentiellt oskäliga skatteuttag. Särskild uppmärksamhet ägnas åt frågan om den förenklade tilläggsskatterapportens rättsliga status, risken för dubbelbestraffning i strid med ne

Lidar technology was utilized to non-destructively explore the diverse insect life in the Taï virgin forest of Côte d'Ivoire. This study employed an entomological Lidar scanned at different elevation angles, combined with traditional insect trapping at different canopy heights, to investigate the composition and spatial-temporal distribution of insects within the forest canopy. We detected stratif

This article presents a comprehensive database featuring the digitized, cleaned, geocoded, and linked data of the Swedish manufacturing censuses between 1863 and 1900. The data covers close to the universe of Swedish manufacturing activity and includes establishment-level information on workers, the sum of production value, and toll as output value. The article describes how the data was originall

The use of bio-based materials offers opportunities to mitigate the climate impacts of construction, with buildings potentially acting as carbon sinks. However, it remains unclear what a future bio-based construction sector will look like. One reason for this are diverse socio-technical visions for the use of bio-based construction materials. In this paper, we use discourse analysis across a compr

Combustion properties and combustion chemistry of ammonia (NH₃) are significantly different from those of hydrocarbons and thus require further investigation. NH₃ combustion with oxidizers different from the ambient air can reveal distinct chemistry of NOx formation, which, together with low reactivity, is one of the major obstacles in the direct deployment of ammonia as a practical fuel. In the p

Background: Studies have shown that women are asking for more knowledge and guidance about menopause. The professional competence of midwives encompasses menopause as a potential area of expertise. Midwives have good knowledge of women's health and are used to providing health advice. Aim: The aim was to examine midwives’ experiences of working with menopause counselling. Methods: Data were collec

The Middle Ordovician of the palaeocontinent Baltica provides some of the best preserved and most diverse acritarch assemblages of the lower Palaeozoic. A great number of widely used acritarch genera and species have been described from this area since the 1960s and many of these taxa are considered as biostratigraphically useful for both regional and international correlation. Here, we document t

Purpose/Background: Ultra-high dose rate radiotherapy (RT) has shown potential for differential normal tissue (NT) sparing (a phenomenon termed the “FLASH effect”), particularly for larger fraction doses (>5 Gy). However, transitioning to hypofractionation may increase late-reacting NT toxicity, counteracting the FLASH effect. This study evaluates whether FLASH-RT can provide netsparing for organs

Magnesium (Mg) is an abundant metal which has been used in aviation, medicine, hydrogen energy storage, etc. However, Mg can be rather reactive, and therefore an improved understanding of corrosion and oxidation mechanisms can enhance the efficiency of these processes to control and widen applications. The study presented here investigates the mechanisms of oxidation from the initial to full monol

The effectiveness of exposure and response prevention (ERP), a front-line treatment for obsessive-compulsive disorder (OCD), is contingent on reducing engagement in compulsions, though recent research has found that certain compulsions may be less amenable to ERP. Given the impact of trauma exposure on OCD compulsions, the present study sought to examine whether compulsion-specific differences in

Objectives: 1. To validate catabolic meniscus explant models induced by cytokines: interleukin-6 ​+ ​interleukin-6 receptor ​+ ​tumor necrosis factor alpha (IL6/TNF) and oncostatin M ​+ ​tumor necrosis factor alpha (OSM/TNF). 2. To evaluate three potential anti-catabolic treatments: i) dexamethasone (DEX), ii) a Link-N peptide (Link-N) and iii) a peptide from chondroadherin (CKF). Design: Healthy

Conventional lumped parameter models (LPMs) simulate coronary flow incorporating intramyocardial pressure and vascular compliance, but assuming constant resistance despite its dynamic changes during myocardial contraction. We developed a coronary LPM incorporating time-varying resistance, intramyocardial pressure and vascular compliance to simulate phasic flow, critically evaluating key contributi

Objective: Osteoarthritis (OA) is a common degenerative disease with a genetic contribution. However, no large nationwide family study concerning the heredity of OA has been published. This first nationwide study aimed to determine the familial risks of the main types of OA in twins, full-siblings, half-siblings, and cousins in Sweden. Design: The Swedish Multigeneration register was linked to the

Carbon capture and storage (CCS) has in recent years gained new attention in national and corporate strategies for achieving climate goals. This is for instance seen in Denmark, where CCS was positioned as the largest single mitigation tool in the 2020 Climate Programme. As an example of how international imaginaries of mitigation technologies translate into national settings, this paper explores

The current investigation explores the surface effects of quasiatomic layer etching (Q-ALE) of silicon (Si), focusing on the interplay of process parameters, such as Ar+ ion energy, and their impact on etch rate, surface roughness, and material damage. Using a chlorine-based reactive ion etching tool at varying radio frequency bias voltages, the ion energy distribution and etching characteristics

This study offers novel insights into parents' experiences of healthcare interactions during weight-related visits. Data were collected through the More and Less Europe study, a randomized controlled trial evaluating a parent support program for children (aged 2-6 years) with overweight or obesity in Sweden, Romania, and Spain to capture parents' experiences of healthcare interactions. Semi-struct