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A clinical approach to acute mesenteric ischemia

PURPOSE OF REVIEW: To summarize current evidence on acute mesenteric ischemia (AMI) in critically ill patients, addressing pathophysiology, definition, diagnosis and management.RECENT FINDINGS: A few recent studies showed that a multidiscipliary approach in specialized centers can improve the outcome of AMI. Such approach incorporates current knowledge in pathophysiology, early diagnosis with trip

Supply Chain Risk Governance: Towards a Conceptual Multi-Level Framework

The coronavirus pandemic (COVID-19) is currently putting high pressure on most countries’ critical infrastructures (not only health care), creating huge uncertainties in supply and demand, and disrupting global supply chains. The global crisis will demonstrate the extent to which different parties (countries, public authorities, private companies etc.) can work together and take holistic decisions

Allergic and hypersensitivity conditions in non-specialist care : Flow diagrams to support clinical practice

Most patients presenting with allergies are first seen by primary care health professionals. The perceived knowledge gaps and educational needs were recently assessed in response to which the LOGOGRAM Task Force was established with the remit of constructing pragmatic flow diagrams for common allergic conditions in line with an earlier EAACI proposal to develop simplified pathways for the diagnosi

Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein

Dimethyl sulfoxide (DMSO) is a highly utilized small molecule that serves many purposes in scientific research. DMSO offers unique polar, aprotic and amphiphilic features, which makes it an ideal solvent for a wide variety of both polar and nonpolar molecules. Furthermore, DMSO is often used as a cryoprotectant in cell-based research. However, recent reports suggest that DMSO, even at low concentr

Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601

Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16

Den förste hemiten

Redogörelse för de tidiga lundensiska (och i någon mån uppsaliensiska) studenthemmens tillkomst kopplad till en biografisk skiss över den förste "hemiten" (boende på Thomanders studenthem), Emil Sommarin, respektive ett resonemang huruvida denne kan ses som en "typisk" hemit.

High-connectivity quantum processor nodes using single-ion qubits in rare-earth-ion-doped crystals

We present two protocols for constructing quantum processor nodes in randomly doped rare-earth-ion crystals and analyze their properties. By varying the doping concentration and the accessible laser tunability, the processor nodes can contain anywhere from only a few tens to almost 1000 qubits. Furthermore, the average number of qubits each qubit can interact with, denoted by the connectivity, can

Road safety beyond the automobility norm? : Can Swedish road safety policy escape the automobility norm and facilitate cycling instead - lessons from the Netherlands

Road safety policy rules us in both visible and invisible ways and prioritising one mode often means downgrading another. It has been argued in previous research that road safety policy prioritises car traffic and in that way sustains the automobility norm. This paper focuses on the automobility norm that permeates Swedish road safety policy and how this hampers planning for cycling. It aims to co

Hospital Admission Rate, Cumulative Hospitalized Days, and Time to Admission Among Older Persons With Substance Use and Psychiatric Conditions

Background: Substance use among older persons occurs with medical and psychiatric comorbidities. This study examined the associations of substance use disorder (SUD), psychiatric, and dual diagnoses with 12-month cumulative hospitalized days, hospital admission rate and number of days to first hospitalization.Methods: The cohort of 3,624 individuals (28.2% women) aged 50 years or older was assesse

Challenges for the sustainability of university-run biobanks

Most university biobanks begin like other university research projects, i.e. with an idea conceived by an individual researcher in pursuit of his/her own research interests, publications, funding and career. Some biobanks, however, come to have scientific value that goes beyond the projects that were initially responsible for the collection of the samples and data they contain. Such value may deri

SARS-CoV-2 in exhaled aerosol particles from covid-19 cases and its association to household transmission

BACKGROUND: Covid-19 transmission via exhaled aerosol particles has been considered an important route for the spread of infection, especially during super-spreading events involving loud talking or singing. However, no study has previously linked measurements of viral aerosol emissions to transmission rates.METHODS: During Feb-Mar 2021, covid-19 cases that were close to symptom onset were visited

Multi-beam X-ray ptychography using coded probes for rapid non-destructive high resolution imaging of extended samples

Imaging large areas of a sample non-destructively and with high resolution is of great interest for both science and industry. For scanning coherent X-ray diffraction microscopy, i. e., ptychography, the achievable scan area at a given spatial resolution is limited by the coherent photon flux of modern X-ray sources. Multibeam X-ray ptychography can improve the scanning speed by scanning the sampl

Metagenomic evidence of a novel family of anammox bacteria in a subsea environment

Bacteria in the order 'Candidatus Brocadiales' within the phylum Planctomycetes (Planctomycetota) have the remarkable ability to perform anaerobic ammonium oxidation (anammox). Two families of anammox bacteria with different biogeographical distributions have been reported, marine Ca. Scalinduaceae and freshwater Ca. Brocadiaceae. Here we report evidence of three new species within a novel genus a

Problemdefinitioner i samtal med klienter – ett interaktionistiskt perspektiv

Människobehandlande yrken, såsom socialt arbete, syftar till att identifiera och åtgärda problem i människors liv. Hur skapas en förståelse av vad ett problem innebär? Hur nås enighet i fall där det finns flera motstridande definitioner och förklaringar till vad som ska anses vara problematisk? Detta kapitel handlar om hur en förståelse av ett problem och lösningar på det kan skapas i ett möte melMänniskobehandlande yrken, såsom socialt arbete, syftar till att identifiera och åtgärda problem i människors liv. Hur skapas en förståelse av vad ett problem innebär? Hur nås enighet i fall där det finns flera motstridande definitioner och förklaringar till vad som ska anses vara problematisk? Detta kapitel handlar om hur en förståelse av ett problem och lösningar på det kan skapas i ett möte mel

Applications of phytochemicals against nerve agents in counterterrorism

Terrorism comes in various forms, clear and sometimes ambiguous, by terrorist cells and sometimes by state players. Nerve agent poisoning represents one of the notorious applications of chemistry in the world. Nerve agents have historically instigated major casualties in various parts, heavily impacting lives of civilians by causing debilitating neurological and psychiatric injuries. Nerve agents

Solubility of Aβ40 peptide

In this work we measured, by using a direct approach, the equilibrium solubility of recombinant Aβ40 peptide to be S ​= ​0.36 ​± ​0.15 ​μM in aqueous solution of 20 ​mM sodium phosphate buffer at pH 7.4. Microfluidic diffusional sizing (MDS) and mass spectrometry (MALDI-TOF/TOF) with isotope standard were used to quantify the concentration of soluble Aβ40 species coexisting with formed fibrils. A

Single-shot transverse coherence in seeded and unseeded free-electron lasers: A comparison

The advent of x-ray free-electron lasers (FELs) drastically enhanced the capabilities of several analytical techniques, for which the degree of transverse (spatial) coherence of the source is essential. FELs can be operated in self-amplified spontaneous emission (SASE) or seeded configurations, which rely on a qualitatively different initialization of the amplification process leading to light emi

Wanted : a low-carbon and fair reset

A piece about a just transition to a low-carbon future (contribution to UNESCO Inclusive Policy Lab 'Think pieces' that explores emerging issues in inclusive policies as well as offering cutting edge solutions).