IMPORTANCE: Breast cancer (BC) is the second leading cause of cancer death in women, and there is a substantial disparity in BC mortality by race, especially for early-onset BC in Black women. Many guidelines recommend starting BC screening from age 50 years; however, the current one-size-fits-all policy to start screening all women from a certain age may not be fair, equitable, or optimal.OBJECTI

Plastic pollution is one of the most severe forms of pollution and the high abundance of microplastics (MP) in aquatic ecosystems is already confirmed. Due to their small size and buoyancy, they are highly bioavailable and have been shown to have a wide range of negative impacts. As a result of their high trophic status and long lifespan, aquatic mammals are susceptible to bioaccumulation and biom

Syftet med denna avhandling är att utveckla en ny metod för att producera bilder med syntetisk aperturradar (SAR), med utgångspunkt i scenarier med arbiträr rörelse vad gäller radarsensorn. SAR är en väletablerad metod för att skapa 2- eller 3-dimensionella radarbilder, som traditionellt sett antar att radar-sensorns rörelse är linjär och förutsägbar. Därmed är positionerna för varje radardata-punThe purpose of this thesis is to develop a novel approach to producing Synthetic Aperture Radar (SAR) images, assuming the scenario of arbitrary motion in regards to the radar sensor. SAR is a well-researched method for creating 2- or 3-dimensional radar images, traditionally assuming the radar sensor's motion to be linear and highly predictable. Thus the locations where each radar data is sam

Speciation entails a reduction in gene flow between lineages. The rates at which genomic regions become isolated varies across space and time. Barrier markers are linked to putative genes involved in (processes of) reproductive isolation, and, when observed over two transects, indicate species-wide processes. In contrast, transect-specific putative barrier markers suggest local processes. We studi

BackgroundEvidence suggests that lifestyle activities impact cognitive and mental health in older populations. However, how lifestyle factors are associated with one another, and which factors are most important for cognitive function and mental health has received comparatively little attention.DesignBayesian-Gaussian network analysis was used to investigate unique associations between mental act

Theoretical and empirical studies suggest that the structure and position of hybrid zones can change over time. Evidence for moving hybrid zones has been directly inferred by repeated sampling over time, or indirectly through the detection of genetic footprints left by the receding species and the resulting asymmetric patterns of introgression across markers. We here investigate a hybrid zone form

This contribution investigates possible material expressions of hetero- and homoerotic expressions on the holy island of Helgö and close-by Hundhamra from the Late Iron Age (c. 550-1050 CE).

Denna avhandling belyser välbefinnandeprocesser utifrån två olika angreppssätt: 1)dels teoretiska beskrivningar av personligt växande, där personligt växandedefinieras som den gradvisa processen av förändring i välbefinnande, 2) delsempiriska undersökningar av välbefinnande och mental hälsa med fokus på eleversmentala hälsoprofiler och självuppfattning. Sammanlagt ingår fem studier iavhandlingen, This thesis follows two main lines of inquiry into well-being processes: 1) atheoretical exploration of personal growth, defined as the gradual growth of wellbeing, and 2) an empirical exploration of students’ mental health profiles and sense of self. Altogether five studies are included in the thesis, two of which follow thefirst line of inquiry (articles I and II) and three of which follow the s

BACKGROUND AND OBJECTIVES: Injured pericytes in the neurovascular unit release platelet-derived growth factor β (PDGFRβ) into the cerebrospinal fluid (CSF). However, it is not clear how pericyte injury contributes to Alzheimer's disease (AD)-related changes and blood brain barrier (BBB) damage. We aimed to test if CSF PDGFRβ was associated with different AD- and age-associated pathological changes