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Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
The therapeutic potential of glial cell line-derived neurotrophic factor ( GDNF) for Parkinson's disease is likely to depend on sustained delivery of the appropriate amount to the target areas. Recombinant adeno-associated viral vectors ( rAAVs) expressing GDNF may be a suitable delivery system for this purpose. The aim of this study was to define a sustained level of GDNF that does not affect the
Computation of Asymptotic Least Squares Estimates
Finns det en "evangelikal exegetik"?
I vilken mening kan vi idag tala om en "evangelikal" exegetik? Vad innebär det idag att bedriva exegetik utifrån en evangelikal utgångspunkt och teologi? Är evangelikal exegetik i själva verket ett uttryck för en svunnen tid och gamla polariseringar? Finns det idag nya fronter i bibelsynsfrågorna? Detta är några av de brännande frågor som behandlas av de åtta bidragsgivarna.
A xylanase carbohydrate binding module as a scaffold for molecular diversity
Serial single-photon emission computed tomographic and transcranial doppler measurements for evaluation of vasospasm after aneurysmal subarachnoid hemorrhage
Objective: To assess the clinical value of serial single photon-emission computed tomographic (SPECT) measurements after aneurysmal subarachnoid hemorrhage (SAH). Methods: Thirty-two patients were studied prospectively during the first 26 days after SAH with repeated SPELT measurements; clinical examinations, and transcranial Doppler recordings. Time trends were analyzed with a general linear mode
Caloplaca erecta, a new subfruticose species from New Zealand
Caloplaca erecta Arup & H. Mayrhofer is described here as new to science. It belongs to a group of dwarf-fruticose species, but cannot be accommodated within any of the known species of that group. It forms dense cushions of erect lobes on siliceous rocks, and is known only from Mt. Maungatua. This is the second dwarf-fruticose species of Caloplaca in the Australasian area, in addition to C. c
Development of toxic degradation products during heat sterilisation of glucose-containing fluids for peritonal dialysis: influence of time and temperature
Severe Pasteurella multocida infections in pregnant women
We report 2 cases of severe infections due to Pasteurella multocida, both occurring during pregnancy in previously healthy women. Both women had contact with animals (dog and cat) but neither of them had been bitten. Apart from a slight decrease in IgG levels, no immunological defects could be detected. Both women had received oral phenoxymethylpenicillin in the early phase of the disease, but sti
Transient electromagnetic wave propagation in laterally discontinuous, dispersive media
This paper concerns propagation of transient electromagnetic waves in laterally discontinuous dispersive media. The approach, used here, employs a component decomposition of all fields. Specifically, the propagation operator that maps a transverse field on one plane to another plane is specified. Expansion of this mapping near the wave front determines the precursor or forerunner of the problem.
Einar Hansen 14/11 1902-21/1 1994
Obituary portrait of Dr h.c. Einar Hansen, Danishborn Swedish publisher and great donor to Lund University.
Factors affecting the static shear strength of the prosthetic stem-bone cement interface.
Extraocular muscle is spared upon complete laminin alpha2 chain deficiency: Comparative expression of laminin and integrin isoforms.
Mutations in the gene encoding laminin (LM) alpha 2 chain cause congenital muscular dystrophy. Here, we show that extraocular muscle (EOM) is spared upon complete LM alpha 2 chain absence. The major LM chains in limb muscle basement membranes are alpha 2, beta 1, beta 2 and gamma 1 whereas alpha 2, alpha 4, beta 1, beta 2 and gamma 1 chains are expressed in EOM. Expression of LMoA chain mRNA is fu
Design of Digital Controllers : The Servo Problem
Infection with delta agent in Sweden: introduction of a new hepatitis agent
To investigate the epidemiology of infection with delta (delta) agent in a Swedish city, 181 chronic carriers of hepatitis B surface antigen (HBsAg) and 599 patients with acute, self-limited hepatitis B were analyzed for delta antigen and antibody to delta antigen (anti-delta). The study covered the period from 1970 to 1981. The delta agent was found to have been introduced to this population in 1
Security and Recognition. A Study of Change in Israel's Official Doctrine 1967-1974
Abstract is not available.
Isothermal calorimetry, applied on shelf-life determination for development of fresh juice
The process of entrepreneurial learning: A conceptual framework
The present article seeks to advance the theoretical knowledge of entrepreneurial learning by reviewing and synthesizing available research into a conceptual framework that explains the process of entrepreneurial learning as an experiential process. The framework identifies three main components in the process of entrepreneurial learning: entrepreneurs' career experience, the transformation proces
Breeding biology of the Savi’s Warbler Locustella luscinioides in Portugal.
The breeding biology of a southern population of the little-known Savi’s Warbler Locustella luscinioides is described and compared with other parts of its distribution and other species. Males arrived at the Salreu marshlands, Portugal, in the second week of March whereas females arrived 6–10 days later. Early-arriving males bred earlier and had greater mating and breeding success. Female breeding
The far from equilibrium structure of argon clusters doped with krypton or xenon
Heterogeneous clusters created by doping Ar host clusters with Kr or Xe are shown to have radically different structures from the mixed clusters of the same type created by co-expansion of Ar-Kr or Ar-Xe gas mixtures. In contrast to the co-expansion case, the doped mixed clusters can be produced with Kr or Xe on the surface and Ar in the bulk. With the doping technique it is thus possible to contr