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Local and systemic effects of inhaled AZD9164 compared with tiotropium in patients with COPD.

There is still a need for new agents which improve upon the therapeutic index of tiotropium, the current standard of care for many patients with chronic obstructive pulmonary disease (COPD). We examined in patients with COPD the efficacy of single doses of AZD9164, an M(3)-selective muscarinic antagonist, to identify an appropriate dose-range for future studies. COPD patients (n = 28) inhaled AZD9

Maternal cardiovascular disease risk in relation to the number of offspring born small for gestational age: national, multi-generational study of 2.7 million births.

Abstract Aim: To investigate the risk of small for gestational age (SGA) births in relation to maternal history of cardiovascular disease (CVD) across two generations and additionally to analyse maternal CVD risk based on number of SGA offspring. Methods: We used register data from 1.4 million women and 2.7 million offspring. The outcome measures were risk of being SGA in relation to maternal tota

Antimicrobial resistance in urosepsis: outcomes from the multinational, multicenter global prevalence of infections in urology (GPIU) study 2003-2013.

Primary objective was to identify the (1) relationship of clinical severity of urosepsis with the pathogen spectrum and resistance and (2) appropriateness of using the pathogen spectrum and resistance rates of health-care-associated urinary tract infections (HAUTI) as representative of urosepsis. The secondary objective was to provide an overview of the pathogens and their resistance profile in pa

De inhemska psykologierna: Ett exempel på forskningens kulturella och sociala beroende

In this article the initiation, development and nature of the indigenous psychologies are characterized. The psychologies in question are those versions of psychology that are, mostly non-western, critical reactions to mainstream psychological research. The heterogeneous and complex nature of the indigeneous psychologies are high-lighted. The enterprise of building a (psychological) science on the

Two-color Time-resolved Spectroscopy of Helium Using High-order Harmonics

The radiative lifetime of the 1s2p(1)P state of helium is measured in a two-colour ionization experiment with a 5% accuracy. The state is excited by the 13th harmonic of a tunable 80 ps laser and ionized by a synchronous ultraviolet laser, with a variable time delay. This experiment demonstrates that the high harmonics generated in a jet of rare gas exposed to an intense laser field provide a tuna

Health, Skills and Labor Market Success

This thesis deals with the interplay between education, labor markets and health. It consists of five studies exploiting large-scale administrative datasets from Sweden. The first study asks if health and educational attainment are related within monozygotic twin (MZ) pairs. This is motivated by the literature using MZ twins to estimate the returns to schooling. If a healthier twin tends to get

Occupational therapists' experience of working with immigrant clients in mental health care.

Abstract Sweden's cultural diversity generates considerable challenges for occupational therapists. The aim of this study was to explore experiences and perceptions of occupational therapists working with immigrant psychiatric clients from the Middle East region. The study included interviews with eight occupational therapists employed in mental health care and working in a variety of settings. Th