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Software Engineering activities are information intensive. Research proposes Information Retrieval (IR) techniques to support engineers in their daily tasks, such as establishing and maintaining traceability links, fault identification, and software maintenance. We describe an engineering task, test case selection, and illustrate our problem analysis and solution discovery process. The objective o

During the past decade it has become evident that immunological, infl ammatory and vascular processes play an important role in the etiology and pathogenesis of various neuro-degenerative diseases. Alzheimer's disease (AD) is a complex and genetically heterogeneous disease that is the most common form of dementia and aff ects up to 15 million individuals worldwide. Th e presenting pathology of AD

The worldwide growing demand for whey proteins and derivatives requires more efficient and sustainable whey protein production processes. Whey is an important by-product from cheese manufacturing. In whey industry membrane processes such as microfiltration, ultrafiltration, nanofiltration and reverse osmosis are well-established to concentrate, fractionate and purify whey proteins as well as whey

Fouling is a constant challenge in membrane-based technologies. As conventional fouling monitoring and control methods are often based on process performance or product quality, they might reveal fouling so late that it has already damaged the membrane in severe and non-reversible way. Thus, surface sensitive online monitoring techniques capable of providing early warning capacity and information

Measurements of jet activity in top-quark pair events produced in proton–proton collisions are presented, using 3.2 fb- 1of pp collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS experiment at the Large Hadron Collider. Events are chosen by requiring an opposite-charge eμ pair and two b-tagged jets in the final state. The normalised differential cross-sections of top-quark p

To assess the benefits of introducing Agile practices, it is important to get a clear understanding of the baseline situation, i.e. the situation before their introduction. Without a clear baseline, we cannot properly assess the extent of impacts, both positive and negative, of introducing Agile practices. This paper provides a preliminary guideline to help researchers in capturing and reporting b

Software developing organizations strive to achieve flexibility to maintain a competitive advantage. There is no common understanding of what characterize flexibility for a software organization beyond the scope of the software product. Without a common understanding, it is difficult to evaluate the degrees of flexibility of software development approaches. The aim of this literature review is to

Periodic boundary conditions (PBC) are well suited to describe repetitive structures in space, yet flawed for isotropic setups in which it is commonly used. We present an approach based on exploiting the congruency of a unit cell which combines the periodic nature of PBC with isotropy of an alternating cell. By applying these isotropic periodic boundary conditions (IPBC) to the standard Ewald summ

Purpose: This study examined if speed reduction effects from animal-vehicle collision (AVC) countermeasures are merely local or do extend to a wider area, and what implications the results have on road planning practice regarding AVCs. Methods: Twenty-five drivers drove repeatedly on a 9-km long road stretch in a high-fidelity driving simulator. The development of vehicle speed in the surrounding

DevOps as a new way of thinking for software development and operations has received much attention in the industry, while it has not been thoroughly investigated in academia yet. The objective of this study is to characterize DevOps by exploring its central components in terms of principles, practices and their relations to the principles, challenges of DevOps adoption, and benefits reported in t

Cisterna magna cannulation (CMc) is a straightforward procedure that enables direct access to the cerebrospinal fluid (CSF) without operative damage to the skull or the brain parenchyma. In anesthetized rodents, the exposure of the dura mater by blunt dissection of the neck muscles allows the insertion of a cannula into the cisterna magna (CM). The cannula, composed either by a fine beveled needle

We test asteroseismic radii of Kepler main-sequence and subgiant stars by deriving their parallaxes which are compared with those of the first Gaia data release. We compute radii based on the asteroseismic scaling relations as well as by fitting observed oscillation frequencies to stellar models for a subset of the sample, and test the impact of using effective temperatures from either spectroscop

In recent years, there has been significant shift from rigid development (RD) toward agile. However, it has also been spotted that agile methodologies are hardly ever followed in their pure form. Hybrid processes as combinations of RD and agile practices emerge. In addition, agile adoption has been reported to result in both benefits and limitations. This exploratory study (a) identifies developme

Cleaning is an inevitable, and often costly, part of most membrane filtration plants. The economic assessment of cleaning costs is often rather arbitrary when researchers design and estimate costs of a membrane plant in a new application. Severity of fouling, operation conditions, cleaning agents and cleaning frequency all influence the costs for membrane cleaning. In addition to the costs of the

Biorefineries are the backbone of “white biotechnology”, the 3rd wave of biotechnology which aims to replace classic C2/C3 chemistry by biotechnological processes. In analogy to petrorefineries biorefineries aim at the integrated and simultaneous production of bulk products, as e.g. biofuels, or biopolymers, heat and power, using biomass. In order to avoid any competition with food production the

Protein-protein interactions play important roles in regulating human aquaporins (AQP) by gating as well as trafficking. While structural and functional studies have provided detailed knowledge of AQP transport mechanisms, selectivity as well as gating by conformational changes of loops or termini, the mechanism behind how protein-protein interactions control AQP-mediated water transport through c

The production of 1 ton of PVC requires 2.0 - 2.5 m3 of demineralised water. Some of the water is lost in the process, e.g. as vapor during the drying of the PVC or as sealing water, while approx. 80% of the water could potentially be recycled. In today’s installations only about 20 – 25% of the water recovered by the PVC decanter is used for flushing of the facilities, while 75 – 80% is discharge

I höst är det 50 år sedan Skärholmens centrum invigdes, ett av de områden som tydligast kommit att symbolisera det svenska miljonprogrammet. Men rekordårens bostadspolitik styrdes inte av en kallhamrad socialdemokratisk människosyn.

„White biotechnology“- the third and latest wave of biotechnology - is aiming to replace the well-established C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. One of the key concepts related to “white biotechnology” are so