Purpose: Preclinical studies using ultra-high dose rate (FLASH) irradiation have demonstrated reduced normal tissue toxicity compared with conventional dose rate (CONV) irradiation, although this finding is not universal. We investigated the effect of temporal pulse structure and average dose rate of FLASH compared with CONV irradiation on acute intestinal toxicity. Materials and Methods: Whole ab

BACKGROUND: Despite an increase in work-life balance literature, the development of successful support to help employees manage their work -life balance is slow. Moreover, there are few interventions with a comprehensive approach to workplace health promotion focusing on work-life balance. OBJECTIVE: This paper aims to present the development and building blocks of a holistic interdisciplinary hea

This chapter describes a study focusing on electrochemically assisted biosensors. Electrochemical regeneration of electron-transfer mediators or cofactors, such as NAD+ has been extensively applied in redox reactions catalyzed by oxidoreductases. This electrochemical regeneration shows many advantages in use of amperometric biosensors, such as extended linear range. To demonstrate the feasibility

Status Epilepticus (SE) is often a neurological emergency characterized by abnormally sustained, longer than habitual seizures. The new ILAE classification reports that SE “…can have long-term consequences including neuronal death, neuronal injury…depending on the type and duration of seizures”. While it is accepted that generalized convulsive SE exerts detrimental effects on the brain, it is not

Gene fusions have been discussed in the scientific literature since they were first detected in cancer cells in the early 1980s. There is currently no standardized way to denote the genes involved in fusions, but in the majority of publications the gene symbols in question are listed either separated by a hyphen (-) or by a forward slash (/). Both types of designation suffer from important shortco

The growing menace of global warming and restrictions on access to water in each region is a huge threat to global hydrological sustainability. Hence, the perspective at which hydrological studies are currently being carried out across the world to quantify and understand the water cycle modeling requires a further boost. In the past few decades, the theoretical understanding of machine learning (

The health and welfare of older adults have raised increasing attention due to global aging. Cycling is a physical activity and mode of transportation to enhance the mobility and quality of life among older adults. Nevertheless, the planning strategies to promote cycling among older adults are underutilized. Therefore, this paper describes the nonlinear associations of the built environment with c

In quantum scattering processes between two particles, aspects characterizing the strong and Coulomb forces can be observed in kinematic distributions of the particle pairs. The sensitivity to the interaction potential reaches a maximum at low relative momentum and vanishing distance between the two particles. Ultrarelativistic heavy-ion collisions at the LHC provide an abundant source of many had

Glutamatergic vesicles in hippocampal mossy fiber presynaptic boutons release zinc, which plays a modulatory role in synaptic activity and LTP. In this work, a fluorescence microscopy technique and the fluorescent probe for cytosolic zinc, Newport Green (NG), were applied, in a combined study of autofluorescence and zinc changes at the hippocampal mossy fiber-CA3 synaptic system. In particular, th

The aim of this study was to explore and describe service user experiences of how receiving services from a Flexible Assertive Community Treatment (FACT) team may support or inhibit citizenship. Within a participatory design, individual interviews with 32 service users from five Norwegian FACT teams were analyzed using thematic, cross-sectional analysis. The findings showed that FACT may support c

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. CRYAB gene, which encodes alpha B-crystallin (a member of small heat shock protein), was reported as a potential autoimmune target. In this study we investigated whether SNPs in the promoter region of CRYAB gene were also important in the etiology of Type 1 diabe

The results of a search for electroweakino pair production pp→χ~1±χ~20 in which the chargino (χ~1±) decays into a W boson and the lightest neutralino (χ~10), while the heavier neutralino (χ~20) decays into the Standard Model 125 GeV Higgs boson and a second χ~10 are presented. The signal selection requires a pair of b-tagged jets consistent with those from a Higgs boson decay, and either an electr

INTRODUCTION AND OBJECTIVE: Several prediction models for falls/near falls in Parkinson's disease (PD) have been proposed. However, longitudinal predictors of frequency of falls/near falls are poorly investigated. Therefore, we aimed to identify short- and long-term predictors of the number of falls/near falls in PD.METHODS: A prospective cohort of 58 persons with PD was assessed at baseline (mean

Since tillage can reduce the amount of organic C stored in soils, the use of conservation tillage practices, which exclude soil inversion, or include it less frequently, is often promoted. Soil microorganisms are closely linked to soil organic C (SOC), and they are assumed to respond quicker to management changes than SOC. Using two Swedish long-term tillage experiments, our aim was to determine w

Wrist-worn devices are popular for heart rate monitoring, including use of photoplethysmography. The Apple Watch series 4 can identify atrial fibrillation. We describe a case of identification re-entrant supraventricular tachycardia not identified by outpatient rhythm monitoring, however, was identified by the Apple Watch series 4, which lead to electrophysiology study and successful ablation of a

Introduction of exogenous genetic material into primary stem cells is essential for studying biological function and for clinical applications. Traditional delivery methods for nucleic acids, such as electroporation, have advanced the field, but have negative effects on stem cell function and viability. We introduce nanostraw-assisted transfection as an alternative method for RNA delivery to human

In this work we report the impact of using mid-infrared laser-induced thermal grating spectroscopy (IRLITGS) for temperature measurements in flames by probing hot water lines. The measurements have been performed in the product zone of laminar atmospheric CH 4 /H 2 /air flat flames with equivalence ratio ranging between 0.6 and 1.05. LITGS is a technique based on thermalization through collisions