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Impacts of mobility disability and high and increasing body mass index on health-related quality of life and participation in society: a population-based cohort study from Sweden

Background: Increasing obesity in adults with mobility disability has become a considerable health problem, similar to the increasing trend of obesity in the general population. The aims of this study were to investigate the association of mobility disability with overweight status and obesity in a large population-based Swedish cohort of adults, and to investigate whether mobility disability, hig

Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

Background: Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional indepen

Direct Formula to Compute Wave Height and Angle at Incipient Breaking

The purpose of this technical note is to present a new formula to compute the incipient breaking wave properties based on a simplified solution of the wave energy flux conservation equation combined with Snell's law. The execution time and calculated results of the new formula were compared with those of the iterative method which is commonly used in coastal engineering calculations, including in

Improvement of rotational CARS thermometry in fuel-rich hydrocarbon flames by inclusion of N-2-H-2 Raman line widths

In rotational coherent anti-Stokes Raman spectroscopy (CARS) thermometry applied to air-fed flames, the temperature sensitivity mainly depends on the intensity distribution of the nitrogen spectral lines. Temperatures are estimated by numerical fitting of theoretical spectra to experimental ones, and one uncertainty in the calculation of theoretical CARS spectra for specific flame conditions is th

Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors

3-Deoxy-3-amino-beta-D-talopyranosides have been synthesized for the first time. The amines were obtained from galactopyranosides through 2,3-anhydrogulosides that were opened to idosides followed by an oxidation/reductive amination sequence. From the amines, 11 corresponding 3-deoxy-3-arylamido-beta-talopyranosides have been synthesized and evaluated as inhibitors against galectin-1, -2, -3, -4C,

Associations of Supermarket Characteristics with Weight Status and Body Fat: A Multilevel Analysis of Individuals within Supermarkets (RECORD Study)

Purpose: Previous research on the influence of the food environment on weight status has often used impersonal measures food environment defined for residential neighborhoods, which ignore whether people actually use the food outlets near their residence. To assess whether supermarkets are relevant contexts for interventions, the present study explored between-residential neighborhood and between-

A PLL based 12 GHz LO generator with digital phase control in 90 nm CMOS

A 12 GHz PLL with digital output phase control has been implemented in a 90 nm CMOS process. It is intended for LO signal generation in integrated phased array transceivers. Locally placed PLLs eliminate the need of long high frequency LO routing to each transceiver in a phased array circuit. Routing losses are thereby reduced and the design of integrated phased array transceivers becomes more mod

Tumour vessel damage resulting from laser-induced hyperthermia alone and in combination with photodynamic therapy

This study examined tumour vessel injury resulting from laser-induced hyperthermia alone and in combination with photodynamic therapy (PDT) in the treatment of rat liver tumours by means of scanning electron microscopy. A total of 18 Wistar rats were divided into three groups, Group I (six animals) underwent hyperthermia for 15 min (15-min hyperthermia). Group II (six animals) underwent hypertherm

Three-Year Survival and Stroke Recurrence Rates in Patients With Primary Intracerebral Hemorrhage.

BACKGROUND AND PURPOSE: There are few studies on the prognosis after primary intracerebral hemorrhages, and they reported big differences in mortality rates. Our aim was to evaluate mortality and stroke recurrence rates in relation to hemorrhage characteristics, demographic and clinical factors, in a large unselected patient cohort. METHODS: We analyzed consecutive cases of first-ever primary intr

Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and delta aminolevulinic acid sensitisation

Background and aims-Laser induced fluorescence (LIF) from colonic mucosa was measured in vivo with and without delta aminolevulinic acid (ALA) in an attempt to differentiate between neoplasia and non-neoplasia in real time during colonoscopy. Methods-Spectra from 32 adenomas, 68 normal sites, and 14 hyperplastic polyps in 41 patients were obtained with a point monitoring system. Twenty one of the