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Glucose-dependent insulinotropic polypeptide (GIP) receptor knockout (KO) mice are tools for studying GIP physiology. Previous results have demonstrated that these mice have impaired insulin response to oral glucose. In this study, we examined the insulin response to intravenous glucose by measuring glucose, insulin and C-peptide after intravenous glucose (0.35 g/kg) in 5-h fasted female GIP recep
This article is a revised version of a keynote given at the 18th Nordic Conference on Systematic Theology: Hope in Dark Times, held in Stavanger on 10–13 January 2019. The aim of the article is to ponder how Jewish and Christian discourses on hope can contribute in a critical way to contemporary political and philosophical discussions of hope. Taking its cue from the biblical idea of messianic red
Purpose: The purpose of the study was to investigate if surface guided radiotherapy (SGRT) can decrease setup deviations for tangential and locoregional breast cancer patients compared to conventional laser-based setup (LBS). Materials and Methods: Both tangential (63 patients) and locoregional (76 patients) breast cancer patients were enrolled in this study. For LBS, the patients were positioned
The world of cult cinema is dotted with numerous films that are often characterised by event-like evening screenings in independent or art-house cinemas years or even decades after the film’s initial release. One film synonymous with the cult cinema circuit is Tommy Wiseau’s The Room (2003), which has often been hailed as the ‘Citizen Kane of bad movies’ due to the film’s lack of artistic vision,
Urban planning is the most relevant decision-making process affecting urban regulating ecosystem services. However, a clear understanding of the effects of planning decisions on both the supply and demand of urban regulating ecosystem services is still lacking. To support planners in enhancing urban regulating ecosystem services, there is a need to understand what variables are at stake and how ch
Urban spatial development is a crucial issue for spatial planning and urban governance, ultimately determining cities’ sustainability. While a set of spatial strategies to address urban development are progressively gaining international consensus, their actual applicability is still contested. An interesting test-bed is represented by the European Union (EU), where common spatial strategies have
As urban systems continue to grow worldwide, urban peripheries increase in number and typologies, which makes their planning a challenge for sustainable development. The aim of this article is to explore approaches and challenges related to the application of sustainable planning to urban peripheries. We reviewed the content of 102 papers related to sustainable planning in urban peripheries by app
Nature-based recreation is among the most relevant ecosystem services supplied by urban green infrastructure, affecting citizens' physical and mental wellbeing. Providing adequate green spaces for nature-based recreation is among the main goals of urban planning, but commonly-used indicators offer a partial view on the issue. Innovative methods and approaches, such as the ESTIMAP-recreation model,
In cities, land-use decisions made during planning processes determine the availability of ecosystem services fundamental to the wellbeing of urban population. Hence, the inclusion of ecosystem services in planning is essential to promote sustainable urban development. This article investigates to what extent ecosystem services are currently included in urban plans. The ultimate objective is to un
This study explores the use of ecosystem service (ES) knowledge to support urban planning in the assessment of future scenarios. The case study concerns the prioritszation of brownfield regeneration interventions in the city of Trento (Italy). Alternative planning scenarios considering the conversion of existing brownfields into new urban parks are assessed and compared. The assessment focuses on
Observations in vivo in patients, supported by guinea-pig in vivo data, take centre stage in this perspective. Its objective is to highlight dichotomies between asthma features observed in vivo and accepted views involving cell/molecular biology research paradigms. For example, increased bronchial epithelial permeability is now considered a major paradigm and trait of asthma, yet, absorption of in
BACKGROUND: Long QT syndrome (LQTS) is caused by the abnormal function of ion channels, which may also affect atrial electrophysiology and be associated with the risk of atrial fibrillation (AF). However, large-scale studies of AF risk among patients with LQTS and its relation to LQTS manifestations are lacking. We aimed to assess the risk of AF and its relationship to the LQTS genotype and the lo
The degree of trophic specialization determines the ability of predators to cope with changing foraging conditions, but in predators that prey on hundreds of species it is challenging to assess, especially when prey identity varies among predator individuals and across space and time. Here, we test the hypothesis that a bat species foraging on flying insects like moths will show ample flexibility
Recent years have seen considerable advancements in Demand Controlled Ventilation (DCV) systems aimed to improved energy efficiency and indoor environmental quality in buildings. A significant aspect of DCV systems is their impact on the acoustic comfort in buildings. This study is part of the Urban Tranquility project with a focus on innovative DCV systems. The objective is to add more understand
Sustainability attributes of building ventilation products have considerable impacts on building performance aspects such as energy efficiency and indoor environmental quality. Heating, Ventilation and Air Conditioning (HVAC) manufacturers allocate resources to develop innovating ideas for improving the sustainability attributes of their products. The diffusion of those sustainable innovations, ho
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