The anti-inflammatory effect of purified honey bee venom (HBV) was studied using a recently described animal model in which preformed immune complexes were injected into rabbit knee-joints. As little as a single injection of 1.2 micrograms HBV/kg body weight subcutaneously significantly reduced the immune complex induced joint inflammation as measured by reduction in leukocyte counts in the joint

A convenient synthesis of benzene-1,3,5-tricarbaldehyde was developed as well as benzaldehyde derivatives carrying one or two latent aldehyde groups. The asymmetric derivatives may serve as versatile scaffolds for the synthesis of sectorial dendrimers and multifunctional molecules.

The Arctic has become an important region in which to assess the impacts of current climate variability and amplification of projected global warming. This is because i) the Arctic has experienced considerable warming in recent decades (an average of about 3°C and between 4° and 5°C over much of the landmass); i) climate projections suggest a continuation of the warming trend with an increase in me

This project is a continuation of the research project: Public transport in Dar-es-Salaam, Tanzania; institutional challenges and opportunities for a sustainable transport system carried out from 2003 to 2004. This study analyses mechanisms, forms for involvement and participation in planning for public transport. Questions asked are: How can participatory transport planning involving the supplier

AMP-activated protein kinase (AMPK) is a key molecular regulator of cellular metabolism, and its activity is induced by both metformin and thiazolidinedione antidiabetic medications. It has therefore been proposed both as a putative agent in the pathophysiology of type 2 diabetes and as a valid target for therapeutic intervention. Thus, the genes that encode the various AMPK subunits are intriguin

We compared the use of Norian SRS, an injectable calcium phosphate bone cement, with functional treatment of redisplaced distal radial fractures in a prospective randomized study of 20 patients. The redisplaced fractures were either rereduced and stabilized by Norian SRS, or the displaced position was accepted and was not rereduced. All wrists were immobilized in a short-arm dorsal splint for 1 we

This study with the Civil Aircraft for Regular Investigation of the Atmosphere Based on an Instrument Container (CARIBIC) platform investigates the aerosol elemental concentrations at 9-11 km altitude in the northern hemisphere. Measurements from 31 intercontinental flights over a 2-year period between Germany and Sri Lanka/Maldives in the Indian Ocean are presented. Aerosol samples were collected

Background--The clinical benefits of lipid lowering with statins are attributed to changes in plaque composition leading to lesion stability, but supporting clinical data from human studies are lacking. Therefore, we investigated the effect of 3 months of pravastatin treatment on composition of human carotid plaques removed during carotid endarterectomy. Methods and Results--Consecutive patients w

Popular Abstract in Swedish Kontrollmekanismerna rörande blodcirkulationen i den mänskliga fetoplacentära enheten är fortfarande inte fullständigt kända, trots genomgripande undersökningar. Det är dock känt att den är viktig för att kunna bibehålla en normal graviditet och för att kunna frambrigna ett friskt nyfött barn. Om kontrollen brister kan utgången försämras i form av tillstånd såsom preeklIn this present study the population of endothelin-like receptors in the human umbilical artery was examined in vitro in different parts of the umbilical cord. Immunohistochemistry revealed ETB receptors in the endothelium and an uneven distribution of ETA receptors in the smooth muscle of the arterial wall, when comparing different parts of the umbilical artery. ET-1 induced vasoconstriction wa

The Swedish inventor Christopher Polhem had an idea of a universal language which occupied him for decades, i.e. a perfect language which can be spoken and understood by everyone, by the educated and non educated alike, and no matter where they come from. Polhem did a large number of sketches for such a universal language, among others a manuscript concerning a lunar language, which was completely