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One-way wave operators for nonstationary dielectrics

Propagation of transverse electric and magnetic (TEM) pulses in nonstationary, linear, homogeneous, and isotropic dielectric and magnetic materials is investigated using an exact wave splitting. Key intrinsic properties are the index of refraction and the relative admittance, which are both temporal integral operators with kernels that depend on two time variables. In addition, the Sommerfeld fore

Ekokardiografi förfinar diagnostiken vid hjärtsvikt

Eko-doppler med vävnadsdoppler ger säkrare hjärtsviktsdiagnostik och kan utföras vid sängkanten. Vävnadsdoppler har givit ny insikt i patofysiologin vid hjärtsvikt. Färgvävnadsdoppler är grunden för parametriska hjärtbilder och kan användas för icke-invasiv skattning av fyllnadstryck. Systolisk och diastolisk funktion är alltid kopplade. Man bör därför använda begreppen »svikt med normal EF« respe

30 år av framgångsrik mykobakterieforskning. AHRI i Addis Abeba ­ unik forskningsmiljö i u-land

The Armauer Hansen Research Institute (AHRI) in Addis Abeba, Ethiopia, was established by the Swedish and Norwegian Save the Children organisations in collaboration with the University of Bergen, with the principal objective of pursuing basic research in leprosy. The institute has a commendable record of achievement, and has made significant contributions to our understanding of leprosy and its co

Characterization of two distinct aryl hydrocarbon receptor (AhR2) genes in Atlantic salmon (Salmo salar) and evidence for multiple AhR2 gene lineages in salmonid fish

The aryl hydrocarbon receptor (AhR) mediates the toxicity of several environmental contaminants, e.g. 2,3,7,8-tetrachlorodibenzo-p-dioxin, and other halogenated hydrocarbons in vertebrates. This receptor initiates the transcription of several biotransformation enzymes, which in turn are responsible for causing severe harm to biological tissue. Here we describe the isolation and complete characteri

On-line diagnostic tool for measurement of the time delay between two ultrashort light pulses

Ultrafast accelerator-based sources combined with synchronized femtosecond lasers are currently being developed. The method described here is intended as a jitter monitor at such facilities. We report on the possibility of extracting a time-offset signal between two different synchronized ultrashort light pulses. The method is based on sum-frequency generation in a nonlinear crystal. Aiming at ext

Development of lentiviral vectors for CNS gene transfer

Popular Abstract in Swedish Att leverera ett läkemedel till hjärnan är svårt då blod-hjärnbarriären effektivt stoppar de flesta kemiska substanser eller kräver att läkemedlet ges i höga systemiska doser. Om läkemedlet passerar blod-hjärnbärriaren påverkar det i så fall alla strukturer och celltyper. Detta är problematiskt i hjärnan då det här finns avgränsade strukturer med olika funktion, ibland Gene therapy in the brain is a promising treatment strategy that in the future may be used for several brain disorders, including Parkinson's disease, Alzheimer's disease and lysosomal storage diseases. By introducing a new gene, rather than providing a classical pharmacological drug, gene therapy offers the opportunity to treat neurological disorders by a single intervention. However, gene therap

Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA.

Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard reagent panel. The panel was designed by a group of HPV experts, and samples were prepared and distributed by the World Health Organization International Laboratory for Standards and Biologicals in The Ne

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues

Using PCR with degenerate primers and screening of a human B-cell lymphoblast cDNA library, a full-length cDNA encoding a 375-amino-acid protein was isolated. It contains seven regions of hydrophobic amino acids probably representing membrane-spanning domains of a novel heptahelix receptor, tentatively named CMKRL2. It shows nearly 30% overall identity with the high-affinity IL8 receptor and simil

Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the European Association for Endoscopic Surgery.

Background Measuring health-related quality of life (QoL) after surgery is essential for decision making by patients, surgeons, and payers. The aim of this consensus conference was twofold. First, it was to determine for which diseases endoscopic surgery results in better postoperative QoL than open surgery. Second, it was to recommend QoL instruments for clinical research. Methods An expert panel

Strategies for feeling secure influence parents' participation in care

This study investigates what makes parents of hospitalized children feel secure and factors influencing their level of participation. It also studies, whether the degree to which parents participate affects their child's pain and sleep during hospitalization. Questionnaires were distributed to a series of parents whose children were discharged from two paediatric surgical wards and one paediatric

Plasma levels of persistent organohalogens and hormone levels in adult male humans

In this study the authors assessed the possible relationship between high dietary exposure to persistent organohalogens (OHS) through fatty fish from the Baltic Sea and hormone levels in adult men. Blood samples were drawn from 110 men who consumed varying amounts of fish (i.e., 0-32 meals per month) for analysis of plasma levels of 18 polychlorinated biphenyl (PCB) congeners, 5 hydroxy-PCBs, 1,1,

Buoyancy Effects on Developing Laminar Gas Flow and Heat Transfer in a Rectangular Fuel Cell Duct

Using a general 3-D finite-volume code, the development of buoyancy force driven secondary flow and its effects on developing laminar flow and heat transfer have been numerically simulated for a horizontal fuel cell duct with a rectangular cross section. The constant thermal-properties assumption except for linear density variation with temperature in the body force term is applied, and a constant

Patch-clamp characterisation of somatostatin-secreting -cells in intact mouse pancreatic islets

The perforated patch whole-cell configuration of the patch-clamp technique was applied to superficial cells in intact mouse pancreatic islets. Three types of electrical activity were observed corresponding to alpha-, beta- and delta-cells. The delta-cells were electrically active in the presence of glucose but lacked the oscillatory pattern seen in the beta-cells. By contrast, the alpha-cells were

Fetal antigen 1 (FA1) in the adult rat adrenal gland, ovary and pituitary gland

Fetal antigen 1 (FA1) is a circulating glycoprotein containing six epidermal growth factor (EGF)-like repeats. FA1's larger membrane-bound precursor is defined by the cDNAs referred to as either human delta-like (dlk) or human adrenal specific cDNA, pG2. In rodents FA1 has also been studied under the names of preadipocyte factor 1 (Pref-1), and zona glomerulosa-specific factor (ZOG). FA1 is abunda