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Cloning of the extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer
A large region containing the extra sex combs (esc) gene of Drosophila has been cloned by microdissection from polytene chromosomes and chromosomal walking. Within this DNA, the segment comprising the esc gene has been narrowed down in several steps. First, a deletion of the esc gene, Df(2L)esc, defined a region of 380 kb. Then, a duplication carrying the esc gene, Dp(2;2)GYL, and a deletion not e
Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells
Preeclampsia (PE) has been associated with placental dysfunction, resulting in fetal hypoxia, accelerated erythropoiesis, and increased erythroblast count in the umbilical cord blood (UCB). Although the detailed effects remain unknown, placental dysfunction can also cause inflammation, nutritional, and oxidative stress in the fetus that can affect erythropoiesis. Here, we compared the expression o
Två roller för beprövad erfarenhet inom hälso- och sjukvård
High-redshift major mergers weakly enhance star formation
Inverse association between serum albumin and depressive symptoms among drug-free individuals with a recent suicide attempt
BACKGROUND AND AIM: Albumin is a protein with multifaceted functions in the human body. According to many studies, lower serum albumin may be associated with depression in various groups of psychiatric and non-psychiatric patients, as well as with attempted suicide. As more severe depressive symptoms have been identified as a reliable risk factor for suicide in patients with high suicide risk, it
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Problem: Groin pain is common in soccer players but the prevalence has only been examined in uncontrolled studies. Methods: 479 male soccer players aged 25 years (17 - 43) (mean with range), 144 female soccer players aged 23 years (16 - 47), 74 men with no history of soccer training aged 26 years (16 - 42) and 94 women with no history of soccer training aged 23 years (range 15 - 43) answered a mai
Testicular cancer, CIS, microcalcifications, TNM classification
Laboratory investigation of myeloproliferative neoplasms (MPNs) : Recommendations of the Canadian MPN group
Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing
Acute leukemias of ambiguous origin
Objectives: This session of the Society for Hematopathology/ European Association for Haematopathology Workshop focused on acute leukemias of ambiguous origin. Methods: We provide an overview of mixed-phenotype acute leukemia (MPAL) as recognized in the current World Health Organization classification and summarize diagnostic criteria for major categories of MPAL: B/myeloid, T/myeloid, B/T, and B/
Genomic analysis of the clonal origin and evolution of acute promyelocytic leukemia in a unique patient with a very late (17 years) relapse
Coiled-coil structure of group A streptococcal M proteins. Different temperature stability of class A and C proteins by hydrophobic-nonhydrophobic amino acid substitutions at heptad positions a and d
M proteins and M-like proteins, expressed on the surface of group A streptococci and binding to human plasma proteins, can be divided into two classes, A and C, depending on the structure of the central repeated regions. The class C proteins have been shown to be dimers with a coiled-coil structure. In this work, we have compared the structure and binding of a class A protein, Mrp4, and a class C
Glueball spectrum in the bag model and in lattice gauge theories
Existing bag-model calculations for the masses of lowest-lying glueball states are extended and reviewed and compared to the present lattice Monte Carlo calculations. The predicted spectra agree remarkably well.
Loop diagrams in boxes
Methods for computing loop diagrams in confined scalar and gauge theories are developed. We construct propagators with different types of boundary conditions in boxes (rectangular cavities) using the method of image charges, which allows for a separation of the short-distance singularities. The techniques are illustrated by a calculation of the Casimir effect in a box using a covariant gauge, and
Colour Dipole Cascades
Effects of target pre-heating and expansion on terahertz radiation production from intense laser-solid interactions
The first experimental measurements of intense laser-driven terahertz (THz) radiation from a solid target which is preheated by an intense pulse of laser-accelerated protons is reported. The total energy of the THz radiation is found to decrease by approximately a factor of 2 compared to a cold target reference. This is attributed to an increase in the scale length of the preformed plasma, driven
Systemic Interpretation of International Human Rights Law in the Jurisprudence of the Inter-American Court of Human Rights
Star clusters in evolving galaxies
Revisiting Stephan's Quintet with deep optical images
Starburst triggered by compressive tides in galaxy mergers
The tidal field of galaxies is known generally to be disruptive. However, in the case of galaxy mergers, a compressive mode of tidal wave may develop and last long enough to cocoon the formation of star clusters. Using an N‐body simulation of the Antennae galaxies, we derive the positions of these compressive regions and the statistics of their duration. Excellent agreement between the spatial dis