The future evolution of global ice sheets under anthropogenic greenhouse forcing and its impact on the climate system, including the regional climate of the ice sheets, are investigated with a comprehensive earth system model consisting of a coupled Atmosphere-Ocean General Circulation Model, a dynamic vegetation model and an ice sheet model. The simulated control climate is realistic enough to pe

Orthogonal P-wave morphology has previously been described in different populations, but its relation to atrial size has not been studied in detail. In this study, we investigated whether atrial size affects P-wave morphology in athletes, who are known to have different degrees of atrial enlargement.

Contrasting ecological conditions may affect the distribution, abundance and impact of parasites and predators throughout the ranges of hosts and prey. Such patterns are evident on the archipelagos of Hawaii and the Galapagos, which vary in their distribution and abundance of avian parasites within and across islands. Previous research has documented higher intensity of parasitic fly larvae (Philo

Recent design experiments have demonstrated that some proteins can switch their folds in response to a small number of point mutations either directly, in a single mutational step, or via intermediate bistable sequences, which populate two different folds simultaneously. Here we explore the hypothesis that bistable intermediates are more common in switches between structurally similar folds while

Background Therapeutic drug monitoring (TDM) of antibiotics in children is of fundamental importance for effective patient management. The use of dried blood spot (DBS) offers a number of advantages over conventional blood collection. The aim of this study is to develop and validate a method to measure piperacillin/tazobactam in DBS. Results The analysis was performed by using LC-MS/MS operating i

This paper deals with a continuous review inventory system with Poisson demand, in which lateral transshipments are allowed. In case of a shortage at a location, another location acts as a supplier, if it is possible. A common assumption in earlier papers is that transshipments are allowed between all locations. This network configuration may, however, not be the best choice for many reasons. one

Book review

Breast cancer survival is reportedly higher in the US than in Europe. The first worldwide study (CONCORD) found wide international differences in age-standardized survival. The aim of this study is to explain these survival differences. Population-based data on stage at diagnosis, diagnostic procedures, treatment and follow-up were collected for about 20,000 women diagnosed with breast cancer aged

Carbon fiber reinforced plastics, CFRP, are attractive materials not only because of their strength and stiffness but also because of their electrical conductivity and high thermal conductivity and diffusivity. One application where induction heating of CFRP is particularly interesting is tools for fast thermal cycling, beneficial inmany industrial processes, for example in composite manufacturingCarbon fiber reinforced plastics, CFRP, are attractive materials not only because of their strength and stiffness but also because of their electrical conductivity and high thermal conductivity and diffusivity. One application where induction heating of CFRP is particularly interesting is tools for fast thermal cycling, beneficial in many industrial processes, for example in composite manufacturin

This note contains a few brief remarks on the similarities and differences between some standard market design applications (e.g., kidney exchange and school choice) and the refugee assignment problem. The main conclusion is that the refugee assignment problem is more complex in some dimensions than many of the standard market design applications. Consequently, classical mechanisms cannot be used

The installation is based on two elements, a re-used tape recorder and a pair of aged wooden planks. The planks are mounted to form a table on which the tape recorder is placed. The sound from the tape recorder is based on field recordings from the area around the municipality Taivalkoski in Northeastern Finland. The tape recorder has formerly been used at The Department of Ethnology at Lund Unive

Hematocrit (HCT) measurements of blood from patients, blood donors and athletes are routinely performed on a daily basis. These measurements are often performed in centralized hospital labs by whole blood analyzers, which leads to long time-to-result. On site measurements, based on centrifugation can be done, but these assays require manual handling, are slow and can just measure HCT in contrast t

We have developed a method to separate bacteria from red and white blood cells (henceforth collectively called blood cells) using acoustophoresis, for subsequent PCR detection. To maximize throughput, we have now investigated the effect of increased cell concentration on the separation. Increasing the blood concentration drastically decreases bacteria recovery, but we show that this can be remedie

Payment and checkout at retail stores is increasingly being replaced by automated systems. One recent technological invention in this area is mobile self-scanning in which customers carry a mobile scanner while shopping. Mobile self-scanners give real-time feedback on spending. The device increases price saliency and enables customers to keep track of the total amount spent. Using a field experime

We present a novel, integrated microfluidic system based on acoustophoretic cell-handling that detects bacteria in whole blood in less than 2 hours, substantially faster than current standard methods for detection of sepsis-causing bacteria. Bacteria are acoustically separated from 1 ml blood, enriched by acoustic trapping and finally detected using a dry-reagent PCR-chip.

A silicon-based microchip for electrochromatographic separations is presented. Apart from a microfluidic network, the microchip has integrated UV-transparent waveguides for detection and integrated couplers for optical fibers on the chip, yielding the most complete chromatography microchip to date in terms of the integration of optical components. The microfluidic network and the optical component

This paper reports simultaneous detection of ultra violet (UV) absorbance and native UV-excited fluorescence in an electrophoresis microchip using UV transparent integrated waveguides. Absorbance detection enables detection of a wide range of analytes. When exposed to UV light, some compounds also exhibit native fluorescence, which is here detected simultaneously. Calibration curves were measured