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Proper skin barrier function is paramount for our survival, and, suffering injury, there is an acute need to restore the lost barrier and prevent development of a chronic wound. We hypothesize that rapid wound closure is more important than immediate perfection of the barrier, whereas specific treatment may facilitate perfection. The aim of the current project was therefore to evaluate the quality

Shaping metals as a foam modulates their physical properties, enabling attractive applications where lightweight, low thermal conductivity, or acoustic isolation are desirable. Adjusting the size of the bubbles in the foams is particularly relevant for targeted applications. Herein, a method with a detailed theoretical understanding of how to tune the size of the bubbles in aluminum melts in situ

The structure of ferroelectric 0.06LiNbO3-0.94K0.5Na0.5NbO3 (KNNL6) was investigated by the neutron total scattering method in the temperature range of 290-773 K. The Rietveld analysis using the powder neutron diffraction data in the range of 290-773 K indicates transition from a two-phase (monoclinic and tetragonal) mixture at room temperature to tetragonal and cubic phases at higher temperatures

Objective: The clinical phenotype of the rare behavioural variant of Alzheimer's disease (bvAD) is insufficiently understood. Given the strong clinico-anatomical correlations of tau pathology in AD, we investigated the distribution of tau deposits in bvAD, in-vivo and ex-vivo, using positron emission tomography (PET) and postmortem examination. Methods: For the tau PET study, seven amyloid-β posit

Background and purpose The role of copy number variation (CNV) variation in stroke susceptibility and outcome has yet to be explored. The Copy Number Variation and Stroke (CaNVAS) Risk and Outcome study addresses this knowledge gap. Methods Over 24,500 well-phenotyped IS cases, including IS subtypes, and over 43,500 controls have been identified, all with readily available genotyping on GWAS and e

Context: Software development is moving towards a place where data about development is gathered in a systematic fashion in order to improve the practice, for example, in tuning of static code analysis. However, this kind of data gathering has so far primarily happened within organizations, which is unfortunate as it tends to favor larger organizations with more resources for maintenance of develo

Aerosol growth of semiconductor nanowires has the potential to dramatically lower the cost of for solar cell production. The objective of the work was to study the growth of aerosol nanoparticles and nanowires, in order to understand the chemical and physical processes involved. This was accomplished by studying the early parts of growths using optical diagnostic techniques. The work involved deve

The science of decision making is studied in many areas of science and engineering, for example within, computer science, automatic control theory, mathematics and neurophysiology. The aim of this text is to provide a very brief overview of some of the models and tools used within mathematical decision making. These models can be studied in terms of an agent that observes the world and takes decisThe science of decision making is studied in many areas of science and engineering, for example within, computer science, automatic control theory, mathematics and neurophysiology. The aim of this text is to provide a very brief overview of some of the models and tools used within mathematical decision making. These models can be studied in terms of an agent that observes the world and takes decis

This is an overview article regarding artificial intelligence (AI) and its potential normative implications. Technology has always had inherent normative consequences not least due to AI and the use of algorithms. There is a crucial difference between algorithms in a technical sense and from a social-science perspective. It is a question of different orders of normativity - the first related to th

Protein–protein interactions are crucial in biology and play roles in for example, the immune system, signaling pathways, and enzyme regulation. Ultra-high affinity interactions (Kd <0.1 nM) occur in these systems, however, structures and energetics behind stability of ultra-high affinity protein–protein complexes are not well understood. Regulation of the starch debranching barley limit dextrinas

Background: There is a growing interest in the contextual effect of neighborhood linking social capital on different health outcomes, including cancer. Aims: To examine associations between neighborhood linking social capital and incidence and mortality of prostate cancer. Method: This cohort study was based on national registers. Between 2002 and 2015, we included 1,196,563 men aged 50 years and

Traumatic brain injury (TBI) and repeated sports-related concussions (rSRCs) are associated with an increased risk for neurodegeneration. Autopsy findings of selected cohorts of long-term TBI survivors and rSRC athletes reveal increased tau aggregation and a persistent neuroinflammation. To assess in vivo tau aggregation and neuroinflammation in young adult TBI and rSRC cohorts, we evaluated 9 hea

The transition from a reliance on fossil resources to the use of renewables for the production of energy, fuels and chemicals is essential for ensuring the sustainability of continued human development. Plant-based biomass is a renewable resource which can be transformed into all of these products. However, biomass is a heterogeneous material composed of several fractions with different chemical p

The presence of rings and gaps in protoplanetary disks are often ascribed to planet-disk interactions, where dust and pebbles are trapped at the edges of planetary-induced gas gaps. Recent works have shown that these are likely sites for planetesimal formation via the streaming instability. Given the large amount of planetesimals that potentially form at gap edges, we address the question of their

Quantum materials having Dirac fermions in conjunction with superconductivity is believed to be the candidate material to realize exotic physics as well as advanced technology. Angle-resolved photoemission spectroscopy (ARPES), a direct probe of the electronic structure, has been extensively used to study these materials. However, experiments often exhibit conflicting results on dimensionality and

Migration represents a major transformation of the lives of those involved and has been transformative of societies and economies globally. Yet models of sustainability transformations do not effectively incorporate the movement of populations. There is an apparent migration-sustainability paradox: migration plays a role as a driver of unsustainability as part of economic globalisation, yet simult

The neutron-deficient gold (Z=79) isotopes in the vicinity of the neutron midshell N=104 provide prolific examples of shape coexistence and isomerism at low excitation energy. They can be probed via a number of different experimental techniques. In this study, two new isomeric states with half-lives of 294(7) and 373(9) ns have been observed in the neutron-deficient odd-odd nuclide Au178 (N=99) in

Two new excited bands built on the πh11/2 configuration have been identified in Nd135 in addition to the known πh11/2 band. The energy spectra of the excited bands and the available electromagnetic transition probabilities are in good agreement with theoretical results obtained using quasiparticle-plus-triaxial-rotor model calculations. The properties of the bands identify them as tilted precessio

The price trend of stocks directly affects the economic interests of investors, and also affects and reflects the country's macroeconomic policies, so it has received widespread attention. The formation and fluctuation of stock prices are not only restricted by various economic and political factors, but also influenced by investment psychology and trading techniques. But in fact, stock prices are