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Automated analysis of song structure in complex birdsongs

Understanding communication and signalling has long been strived for in studies of animal behaviour. Many songbirds have a variable and complex song, closely connected to territory defence and reproductive success. However, the quantification of such variable song is challenging. In this paper, we present a novel, automated method for detection and classification of syllables in birdsong. The meth

Low levels of immunoglobulins and mannose-binding lectin are not associated with etiology, severity, or outcome in community-acquired pneumonia

Background. Disease severity and outcome in community-acquired pneumonia (CAP) depend on the host and on the challenge of the causal microorganism(s). We measured levels of immunoglobulins (Igs) and complement in 257 hospitalized adults with CAP and examined the association of low levels of Igs or complement to microbial etiology, disease severity, and short-term and long-term outcome. Methods. Se

Relationships between multiple biodiversity components and ecosystem services along a landscape complexity gradient

The assessment of effects of anthropogenic disturbance on biodiversity (BD) and ecosystem services (ES) and their relationships are key priorities of the Intergovernmental Panel for Biodiversity and Ecosystem Services. Agricultural landscapes and their associated BD provide multiple ES and it is crucial to understand how relationships between ES and BD components change along gradients of landscap

Transient receptor potential a1 (TRPA1) agonists inhibit contractions of the isolated human ureter

Aims: Mechanoafferent and peristaltic mechanisms of the human ureter involve transient receptor potential V1 (TRPV1)- and purinoceptor-mediated functions. Hydrogen sulphide, an endogenous TRPA1 ligand, is linked to inhibitory neurotransmission of the pig ureter. No information is available on TRPA1 activity in the human ureter. We therefore examined the distribution and function of TRPA1 in the hu

Planet population synthesis driven by pebble accretion in cluster environments

The evolution of protoplanetary discs embedded in stellar clusters depends on the age and the stellar density in which they are embedded. Stellar clusters of young age and high stellar surface density destroy protoplanetary discs by external photoevaporation and stellar encounters. Here, we consider the effect of background heating from newly formed stellar clusters on the structure of protoplanet

The ALICE transition radiation detector: Construction, operation, and performance

The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of t

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes : A prospective study in children

Background: Around 0.3% of newborns will develop autoimmunity to pancreatic beta cells in childhood and subsequently develop type 1 diabetes before adulthood. Primary prevention of type 1 diabetes will require early intervention in genetically at-risk infants. The objective of this study was to determine to what extent genetic scores (two previous genetic scores and a merged genetic score) can imp

Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study

Objectives Our aim was to use the opportunity provided by the European Scleroderma Observational Study to (1) identify and describe those patients with early diffuse cutaneous systemic sclerosis (dcSSc) with progressive skin thickness, and (2) derive prediction models for progression over 12 months, to inform future randomised controlled trials (RCTs). Methods The modified Rodnan skin score (mRSS)

Temperature effects explain continental scale distribution of cyanobacterial toxins

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship b

Regional innovation systems and global flows of knowledge

The literature on regional innovation systems emphasizes the role of the region as locus for interactive learning and knowledge exchange, stressing the importance of (geographical) proximity for innovation. Even though the importance of extra-regional knowledge is widely acknowledged, there has been only little emphasis on the particular role and the nature of global knowledge flows. The aim of th

Conformational Ensembles of Calmodulin Revealed by Nonperturbing Site-Specific Vibrational Probe Groups

Seven native residues on the regulatory protein calmodulin, including three key methionine residues, were replaced (one by one) by the vibrational probe amino acid cyanylated cysteine, which has a unique CN stretching vibration that reports on its local environment. Almost no perturbation was caused by this probe at any of the seven sites, as reported by CD spectra of calcium-bound and apo calmodu

THE ROLE OF BUSINESS MODEL INNOVATION FOR PRODUCT INNOVATION PERFORMANCE

We analyse the effect of business model innovation (BMI) on the product innovation performance of firms, based on a dynamic capabilities theoretical framework. Our empirical study is based on a large-scale representative sample of cross-industry Swedish firms participating in three waves of the Community Innovation Survey (CIS) from 2008 to 2012. We hypothesise that BMI in the form of product inno

Drottningarnas drottning : Jungfru Maria i svensk medeltida cisterciensisk predikan

En handskrift som en gång tillhörde Alvastra kloster, nu Uppsala Universitetsbibliotek C 37, innehåller en delvis kalendariskt ordnad predikosamling nedskriven i början av 1200-talet, utan kända paralleller. Artikeln beskriver samlingen och konstaterar att innehållet har både monastisk och folklig prägel. En möjlig slutsats är att en munk i Alvastra har sammanställt/författat predikningarna för at

Antenna design challenges and solutions for compact MIMO terminals

The design of antennas for compact multiple-input multiple-output (MIMO) terminals is a challenging feat, due to the space constraint and the physical structure of the terminal. The space constraint forces the antennas to be closely spaced, which degrades MIMO performance due to high signal correlation and low antenna efficiency. Moreover, the terminals are equipped with ground planes which furthe

Angle and polarization diversity in compact dual-antenna terminals with chassis excitation

For multiple antennas on a compact terminal chassis, chassis current excitation can severely increase mutual coupling between the antennas. This is because the same characteristic mode of the chassis may be strongly excited by more than one antenna. Here, we propose to use one antenna that exploits chassis excitation and introduce a second antenna that minimizes chassis excitation. In this way, an

Experimental evaluation of MIMO terminal antenna configurations in noise- and interference-limited urban scenarios

In this paper, we compare capacity performances of three terminal dual-antenna configurations at 2.65 GHz based on extensive 2 by 2 multiple-input multiple-output (MIMO) channel measurements in an urban macrocellular environment. Both noise- and interference-limited scenarios are investigated. Our results show that, on average over the measurement route, the capacity performance is mainly determin

Impact of current localization on the performance of compact MIMO antennas

In this paper, we study the influence of current localization on the isolation between two antennas in a compact terminal setting. The two antennas are chosen to be a monopole and a PIFA. The degree of current localization is controlled by the permittivity value of the PIFA’s dielectric loading. Both lossless and lossy cases are simulated in order to ascertain the underlying performance impact fro

On simplifying WINNER II channel model for MIMO OTA performance evaluation

The development of MIMO over-the-air (OTA) test methodology is an ongoing activity in 3GPP RAN4, CTIA and EU COST Action 2100. In this paper, the focus is on the anechoic chamber approach, which uses a uniform circular array of probe antennas to replicate directional channels for the device-under- test at the array center. In particular, we study in simulation the complexity requirements of implem