In Responsibility From the Margins, David Shoemaker distinguishes three forms of responsibility: attributability, answerability, and accountability. The introduction of various normative competence requirements lends precision to the contrasts that Shoemaker draws between these forms of responsibility. I argue, however, that these competence requirements are less well motivated than Shoemaker supp

We approach the semantics of prepositions from the perspective of conceptual spaces. Focusing on purely spatial locative and directional prepositions, we analyze both types of prepositions in terms of polar coordinates instead of Cartesian coordinates. This makes it possible to demonstrate that the property of convexity holds quite generally in the domain of prepositions of location and direction,

Advanced 1-D models for secondary clarifiers aim to incorporate more realism by explicitly accounting for several phenomena that influence the settling process. For each of them a valid mathematical expression needs to be selected to obtain a calibrated model that can be used for operation and control. The presented work evaluates different available expressions for hinderedsettling based on long

We explore in detail the physics potential of a measurement of the t invariant mass distribution. First, we assess the accuracy of the best available predictions for this observable and find that in the low invariant mass region, the shape is very well predicted and could be used to perform a top mass measurement. Second, we study the effects of a heavy s-channel resonance on the t invariant mass

Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [3H]bicuculline methochloride (BMC) to γ-aminobutyric acid (GABA) receptor sites and the binding of [3H]β-carboline-3-carboxylic acid methyl ester (βCCM) to benzodiazepine receptor sites in mammalian brain. These concentration-dependent effects were chemically specific and stereospecific in a mann

Numerous barbiturates, such as (±)-pentobarbital, reversibly enhance the affinity for equilibrium binding of [3H]diazepam to well-washed rat cortical membranes in a chloride-dependent and picrotoxinin-sensitive manner [Leeb-Lundberg et al., Proc. Natl. Acad. Sci. U.S.A. 77:7468-7472 (1980)]. The chemical specificity and stereospecificity of this barbiturate effect in vitro has been examined in det

The two pyrazolopyridines, etazolate (SQ20009) and cartazolate (SQ65396), enhance the binding of [3H]diazepam to benzodiazepine receptor sites in rat brain. This enhancement is due to a change in affinity without a change in maximal binding. Pentobarbital also enhances [3H]diazepam binding by lowering the K(D). Pentobarbital gives a maximal enhancement of benzodiazepine binding slightly greater th

Safeguarding the diversity of natural and semi-natural habitats in Europe is one of the aims set out by the Habitats Directive (Council Directive 92/43/EEC on the conservation of natural habitats and of wild fauna and flora) and one of the targets of the European 2020 Biodiversity Strategy, and is to be accomplished by maintaining a favourable conservation status. To reach this aim a high-level un

Placenta protein 14 (PP14), which is the most abundant product of the secretory endometrium, has been proposed as the best biochemical marker of endometrial function in women. In this study, 19 normogonadotrophic women of infertile couples were monitored with serial measurements of concentrations of PP14, gonadotrophins and sex steroids and ultrasound scanning of endometrial thickness throughout t

Classical conditioning is important in humans to learn and predict events in terms of associations between stimuli and to produce responses based on these associations. Social robots that have a classical conditioning skill like humans will have an advantage to interact with people more naturally, socially and effectively. In this paper, we present a novel classical conditioning mechanism and desc

A number of deleterious health effects have been identified from exposure to outdoor air-borne particulate matter. This issue is complicated by the fact that people are spending most of the time indoors, where particles of both indoor and outdoor origin are present. The aim of this work was to assess the differences in particle chemical composition inside and outside of the residence and gain bett