82 women who had had surgery for removal of breast cancer were randomised during the primary care period before initiation of any chemotherapy or radiotherapy into two groups: no drug treatment (n = 40) and 20 mg tamoxifen per day for 2 years (n = 42). Mononuclear leucocyte (MNL) fractions from blood samples were collected during the first 368 days of the study and ADP-ribosylation was quantified.

Objective. To evaluate the prognostic impact of cytogenetic findings in renal cell carcinoma (RCC). Patients and methods. Tumour cytogenetics, histomorphology, DNA ploidy and S-phase fraction, stage, size, and grade were related to survival in 50 consecutive patients with RCC. The mean follow-up was 3.9 years (median 4.2. range 0-8.8). Results. The predictive probability for recurrence-free surviv

Summary. Breast cancer in women under 30 years old carries a poor prognosis, for reasons that have not been identified. This study aimed to identify prognostic factors in this age group. Special attention was paid to the history of pregnancy. The clinical presentation and course of breast cancer was documented for 407 women, aged 20-29 years, who registered between 1978 and 1988 at one of nine can

Background. There is an increase in the incidence of cutaneous malignant melanoma (CMM) among white people throughout the world. In Sweden, a fivefold increase has been recorded since 1960, but the mortality is rising at a much lower rate. Tumor thickness is the single most important prognostic factor for primary melanoma. This study aimed to clarify whether the thickness of the tumor in invasive

The metabolism of [ 3 H]estrone sulfate ([ 3 H]E 1 S) was studied in normal breast tissue from 10 premenopausal women without oral contraceptives (OC), in 12 OC users and in 9 untreated postmenopausal women. [ 3 H]E 1 S was converted into estrone ([ 3 H]E 1 ) and estradiol-17β ([ 3 H]E 2 ) by tissue samples from all three groups of women, with only minor formation of other unconjugated compounds.

Tobias Norlind (1879–1947) var en allsidig och mycket produktiv vetenskapsman. I denna antologi behandlas olika sidor i hans verksamhet. Vid Lunds universitet var han med om att göra det möjligt att bedriva akademiska studier i musik. Parallellt med detta var han rektor vid flera nya folkhögskolor och undervisade vid dem. Båda dessa sidor fortsatte han med efter att ha flyttat till Stockholm. Där

Denna rapport är resultatet av ett projekt vars syfte har varit att bygga upp en forskningsdatabas över och kartera svenska mikro-/hantverksbryggerier verksamma under främst 2000-talet. Sammanställningen har skett genom insamling, systematisering, lagring, analys och visualisering av bryggeridata utifrån geografiska platser. Forskningsdatabasens användbarhet exemplifieras genom analyser med stöd a

AIMS: Using functional magnetic resonance imaging (fMRI) we investigated the cortical and subcortical representations during bladder filling and the effect of simultaneous stimulation of the dorsal clitoral nerve on these cortical and subcortical structures.METHODS: After approval of the local ethics committee, 8 healthy females were included. Prior to scanning, subjects were catheterized and the