Det ökande byggandet av stadsvägtunnlar, de alpina tunnelolyckorna runt millennieskiftet, och det efterföljande EU-direktiv (2004/54/EC) med minimikrav gällande brandsäkerhet har placerat brandsäkerhet i vägtunnlar högt på dagordningen. Samtidigt är moderna enkelriktade vägtunnlar ofta bland de säkraste delarna av vägsystemet. Har vi kommit till en punkt där resurserna används bättre någon annanstThis thesis can be described as a journey in performance-based fire safety design. Along the way questions such as what fire safety is, how it can be measured, whether we are posing the right questions, or engineer the best solutions, have arisen. The safety journey naturally started out with the traditional view, with fire safety engineering based on limit-based design. Using this paradigm the sa

Space power systems require photovoltaics that are lightweight, efficient, reliable, and capable of operating for years or decades in space environment. Current solar panels use planar multijunction, III-V based solar cells with very high efficiency, but their specific power (power to weight ratio) is limited by the added mass of radiation shielding (e.g., coverglass) required to protect the cells

Background: Quinoa is a pseudocereal with relatively high content of proteins and minerals that also contains mineral inhibitors such as phytate. The aim of the present study was to evaluate lactic acid fermentation and dry roasting on the nutritional quality and sensory attributes of quinoa. Various processes were evaluated, and quinoa grains were dry-roasted, milled, and fermented, either with o

To explore the behavior and mechanisms of heat transfer deterioration (HTD), the flow and thermal performances of supercritical n-decane in upward vertical tubes are investigated with emphasis on the boundary layer. It is realized that the dramatic variation of the thermophysical properties can cause unconventional heat transfer phenomenon and the change of the density is important in particular.

Edit Farkas and László Lőkös are internationally well known and respected Hungarian lichenologists. They did their best to maintain and to develop several aspects of the Hungarian lichenology, including biodiversity research on lichen-forming and lichenicolous fungi, taxonomic revisions based on morphological, chemical and molecular methods, ecological, ecophysiological and conservation biological

The 8.2 ka bp cooling event is assumed to be the most clearly marked abrupt climate event in the Holocene at northern mid- to high latitudes. In this study, we simulate the vegetation responses to the 8.2 ka bp climate change event over Europe and Northern Africa. Our results show that all dominant plant functional types (PFTs) over Europe and North Africa respond to these climate changes, but the

The main purpose of this article is to examine how elite athletes perceive their own responsibilities and possibilities to be compliant with the anti-doping regulations, and to draw conclusions about what these perceptions mean in relation to the legitimacy of the anti-doping system. A qualitative research design, with interviews conducted with athletes globally, was employed to capture elite spor

This paper contributes to the understanding of relational aspects of leadership and followership. Our in-depth empirical study of the leader/follower relation uncovers how and why assigning team members into ‘leader’ and ‘follower’ positions may sometimes be a double-edged sword and lead to unintended consequences undermining both the team’s potential and member satisfaction. We report on a multi-

Pedestrian evacuation models are often used to assess life safety in the performance-based design process within fire safety engineering. Within this paper, a summary of data collected via an international online survey regarding the models and users’ experiences and needs is presented. This survey consisted of 22 questions focusing on: the assessment of the pedestrian evacuation model user commun

Objectives: To describe logarithm of the minimum angle of resolution (logMAR) best corrected visual acuity (BCVA) and intraocular pressure (IOP) after surgical management of late in-the-bag dislocation of the intraocular lens. Subjects/methods: In a single-centre prospective study, 165 consecutive cases having surgical correction for late in-the-bag-dislocation of intraocular lenses were analysed.

AI is expected to be a driver for improved standards of health, reduced costs, decentralized care and facilitated access to healthcare. Its successful implementation depends on technology factors and industrial investments in AI innovation, but also conditional to trust and acceptance by patients, medical staff and healthcare authorities. AI will inevitably change the nature of health care innovat

Post-translational methylation of lysine side chains is of great importance for protein regulation, including epigenetic control. Here, we present specific 13CHD2 labeling of dimethylated lysines as a sensitive probe of the structure, interactions, and dynamics of these groups, and outline a theoretical and experimental framework for analyzing their conformational dynamics using 1H and 13C CPMG re

Galectins are a medically important family of small, soluble carbohydrate-binding proteins that have been implicated in a wide variety of diseases, and are therefore targets for the development of new drugs. Many X-ray crystal structures of small molecules in complex with galectins have been determined and have given invaluable information on how natural ligands and synthetic inhibitors are recogn

Treatment of haemophilia A/B patients comprises factor VIII (FVIII) or factor IX (FIX) concentrate replacement therapy, respectively. FVIII and FIX activity levels can be measured in clinical laboratories using one-stage activated partial thromboplastin time (aPTT)-based clotting or two-stage chromogenic factor activity assays. We discuss strengths and limitations of these assays, providing exampl

A novel model-independent Lévy imaging method is employed for reconstruction of the elastic pp and pp¯ scattering amplitudes at low and high energies. The four-momentum transfer t-dependent elastic slope B(t), the nuclear phase φ(t) as well as the excitation function of the shadow profile P(b) have been extracted from data at ISR, Tevatron and the LHC energies. We found qualitative differences in

Objectives: With increased long-term survival after traumatic brain injury (TBI), there is a need to understand the life situation many years after the injury. In this study, we have assessed persons on average 16 years after their injury and determined changes over 6 years in overall outcome, living condition, marital status and vocational situation, and in their functioning and disability. Mater

Purpose: Postoperative bleeding after thyroid surgery remains a potentially lethal complication. Outpatient thyroidectomy is an increasing trend in the high volume centers. There is a need to identify risk factors for postoperative bleeding in order to select proper patients for outpatient thyroidectomy. This study aimed to investigate this issue using a national population-based register. Materia

Patient participation in forensic psychiatric settings seems to be complex by nature, and previous studies show that patients rate their participation as lower in this context compared to general psychiatric contexts. Studies on caregivers’ perspective could provide a clearer picture of the components and possibilities of patient participation in forensic psychiatry. The aim of the study is to des

Parental care in birds varies among species and geographic regions. Incubation behavior influences embryonic development rate and varies substantially among species. We studied attendance at the nest by videoing nests or collecting data from the literature for 112 species in north temperate and lowland tropical sites, then associated patterns of incubation on- and off-bouts with species and enviro

Amyloid fibril formation is a hallmark of neurodegenerative disease caused by protein aggregation. Oligomeric protein states that arise during the process of fibril formation often coexist with mature fibrils and are known to cause cell death in disease model systems. Progress in this field depends critically on development of analytical methods that can provide information about the mechanisms an