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The role of the active site tyrosine in the mechanism of lytic polysaccharide monooxygenase

Catalytic breakdown of polysaccharides can be achieved more efficiently by means of the enzymes lytic polysaccharide monooxygenases (LPMOs). However, the LPMO mechanism has remained controversial, preventing full exploitation of their potential. One of the controversies has centered around an active site tyrosine, present in most LPMO classes. Recent investigations have for the first time obtained

Contrasting responses of woody and herbaceous vegetation to altered rainfall characteristics in the Sahel

Dryland ecosystems are a major source of land cover, account for about 40% of Earth's terrestrial surface and net primary productivity, and house more than 30% of the human population. These ecosystems are subject to climate extremes (e.g. large-scale droughts and extreme floods) that are projected to increase in frequency and severity under most future climate scenarios. In this modelling study w

Tutankhamon

En forskningsmässigt uppdaterad översikt av Tutankhamon och hans tid i skuggan av den fornegyptiska historien i allmänhet och Akhenatons politisk-religiösa reform i synnerhet.

Gangsterväldet

Om gangsterväldet i New och Chicago på 1920-talet, med utblickar mot den historiska bakgrunden och maffians verksamhet senare under 1900-talet.

Häxprocesserna

En översikt av häxförföljelser från antiken till nutiden, med fokus på europeisk tidigmodern tid.

Centerpartiet och flirten med islamism

Kopplingen mellan islamiska riksorganisationer och Centerpartiet går decennier tillbaka, skriver Sameh Egyptson, forskare i interreligiösa relationer. Partiet har fungerat som inkörsport och ett mål för infiltration från islamistiskt håll.

Tvinga bort ledningen för Folkbildningsrådet

Att organisationer som anklagas för ekonomisk brottslighet utreder sig själva och fortsätter sitta på sina positioner är anmärkningsvärt. Det visar på ett förakt mot skattebetalarna.

Investigation of Fuel and Load Flexibility in a SGT-600/700/800 Burner Under Atmospheric Pressure Conditions Using High-Speed OH-Plif and OH Chemiluminescence Imaging

Fuel and load flexibility have been increasingly important features of industrial gas turbines in order to meet the demand for increased utilization of renewable fuels and to provide a way to balance the grid fluctuations due to the unsteady supply of wind and solar power. Experimental investigations were performed using a standard 3rd generation dry low emission (DLE) burner under atmospheric pre

Core-Level Binding Energy Reveals Hydrogen Bonding Configurations of Water Adsorbed on TiO2 (110) Surface

Using x-ray photoelectron spectroscopy of the oxygen 1s core level, the ratio between intact (D2O) and dissociated (OD) water in the hydrated stoichiometric TiO2(110) surface is determined at varying coverage and temperature. In the submonolayer regime, both the D2O:OD ratio and the core-level binding energy of D2O (ΔBE) decrease with temperature. The observed variations in ΔBE are shown with dens

Experimental Investigation of Plasma Discharge Effect on Swirl Flames at a Scaled Siemens Dry Low Emission Burner

The effect of a Rotating Gliding Arc (RGA) plasma discharge on the flame in a scaled Siemens Dry Low Emission (DLE), SGT-750, burner was experimentally investigated under atmospheric combustion conditions. The central pilot section of the burner, named RPL (rich pilot lean), was redesigned with an integrated high voltage electrode to generate an RGA. The exhaust gas was sampled and analysed in ter

Crosstalk between mast cells and lung fibroblasts is modified by alveolar extracellular matrix and influences epithelial migration

Mast cells play an important role in asthma, however, the interactions between mast cells, fibroblasts and epithelial cells in idiopathic pulmonary fibrosis (IPF) are less known. The objectives were to investigate the effect of mast cells on fibroblast activity and migration of epithelial cells. Lung fibroblasts from IPF patients and healthy individuals were co-cultured with LAD2 mast cells or sti

The nexus of csr and co-creation : A roadmap towards consumer loyalty

Corporate Social Responsibility (CSR) is regarded as an effort to be undertaken by the businesses to contribute towards society at large positively. The idea behind the concept of CSR is that businesses are required to pursue the notion of pro-social objectives along with economic objectives. Research has long established that corporate social responsibility, along with its philanthropic nature, c

A prospective study on effectiveness of elevated intraocular pressure as a criterion for glaucoma referrals by optometric practitioners in Sweden

Purpose: To evaluate the outcome of referrals for suspected glaucoma based on elevated intraocular pressure (IOP) made by optometric practitioners in Sweden. Methods: This prospective study included 95 individuals referred to the Skåne University Hospital Malmö, Sweden, during 2019, by optometric practitioners, based on elevated IOP. Positive outcome was defined as a diagnosis of glaucoma, or a di

Closing the Osteoporosis Care Gap

Purpose of Review: This review outlines the scope of the problem in osteoporosis care and secondary fracture prevention and describes fracture prevention strategies, with a focus on the frail elderly. Recent Findings: Despite heightened awareness among patients and clinicians alike and the availability of efficacious anti-osteoporosis medications, osteoporosis is still underdiagnosed and undertrea

Conformation of Myoglobin-Poly(Ethyl Ethylene Phosphate) Conjugates Probed by SANS : Correlation with Polymer Grafting Density and Interaction

One can take advantage of the influence of a polymer conjugated with a protein to control the thermal stability and the deployment of the protein. Here, the structural properties are reported of the protein–polymer conjugate myoglobin (Mb)-poly(ethyl ethylene phosphate) (PEEP) in the native and unfolded conformations, in order to understand the respective roles of the protein and of the polymer si