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Epidemiology and clinical features of patients with visceral leishmaniasis treated by an MSF clinic in Bakool region, Somalia, 2004-2006

BACKGROUND: There are few reports describing the epidemiology of visceral leishmaniasis (VL) in Somalia. Over the years 2002 to 2005, a yearly average of 140 patients were reported from the Huddur centre in Bakool region, whereas in 2006, this number rose to 1002 patients. Given the limited amount of information on VL and the opportunity to compare features with the studies done in 2000 in this pa

Natural history of a visceral leishmaniasis outbreak in highland Ethiopia

In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the only VL treatment center in the area, maintained by Médecins Sans Frontières-Ethiopia, Operational Center Barcelona-Athens. The median age was 18

Pesticide residues in fruits and vegetables from the southern part of Botswana

This study reports a surveillance of multi-pesticide residues of fruits and vegetables sold in the local markets carried out in 2018–2019 in Botswana to access consumer safety. A validated method for analysis of 232 pesticide residues in fruits and vegetables was applied, based on QuEChERS-GC-MS/MS methodology. A total of 83 fruit and vegetable sold in different markets were bought from three diff

“Omics” in traumatic brain injury : novel approaches to a complex disease

Background: To date, there is neither any pharmacological treatment with efficacy in traumatic brain injury (TBI) nor any method to halt the disease progress. This is due to an incomplete understanding of the vast complexity of the biological cascades and failure to appreciate the diversity of secondary injury mechanisms in TBI. In recent years, techniques for high-throughput characterization and

What happens when municipalities run corporations? Empirical evidence from 290 Swedish municipalities

Local governments are increasingly relying on municipally owned corporations (MOCs) to provide public services. Some describe this development as a rational response to austerity challenges and emphasise the cost-efficiency of MOCs (‘the optimistic view’). Others identify complications and associate MOCs with weak supervision, lack of accountability, and corruption risks (‘the sceptical view’). Hi

Praxitopia : Co-constituting a vibrant local street through shopping

In the last decades shopping’s spatiotemporal manifestations are changed radically in conjunction with proliferation of car usage, internationalization of retail sector, and construction of out-of-town malls (Wrigley & Lowe, 1996; Mansvelt, 2005; Kärrholm & Nylund, 2011; Aslan & Fredriksson, 2017). However, the main empirical focus laid mostly on the mainstream and spectacular geograph

Microfluidic chips provide visual access to in situ soil ecology

Microbes govern most soil functions, but investigation of these processes at the scale of their cells has been difficult to accomplish. Here we incubate microfabricated, transparent ‘soil chips’ with soil, or bury them directly in the field. Both soil microbes and minerals enter the chips, which enables us to investigate diverse community interdependences, such as inter-kingdom and food-web intera

Endo-xylanases from Cohnella sp. AR92 aimed at xylan and arabinoxylan conversion into value-added products

The genus Cohnella belongs to a group of Gram-positive endospore-forming bacteria within the Paenibacillaceae family. Although most species were described as xylanolytic bacteria, the literature still lacks some key information regarding their repertoire of xylan-degrading enzymes. The whole genome sequence of an isolated xylan-degrading bacterium Cohnella sp. strain AR92 was found to contain five

Resistance of Clay Brick Masonry Façades to Wind-Driven Rain : Repointing of Eroded Mortar Joints

Clay brick masonry façades are commonly used due to their high-performance durability. However, exposure to climate agents such as wind-driven rain (WDR), freeze-thaw cycles, and wind abrasion cause deterioration of masonry façades over time. WDR as a significant source of moisture may contribute to the erosion of mortar joints and lead to increased moisture content and risk of water penetration.

Transcriptomic signatures of tumors undergoing T cell attack

Background: Studying tumor cell–T cell interactions in the tumor microenvironment (TME) can elucidate tumor immune escape mechanisms and help predict responses to cancer immunotherapy. Methods: We selected 14 pairs of highly tumor-reactive tumor-infiltrating lymphocytes (TILs) and autologous short-term cultured cell lines, covering four distinct tumor types, and co-cultured TILs and tumors at sub-

Magnetic resonance imaging incidents are severely underreported : a finding in a multicentre interview survey

Objectives: The purpose of this study was to develop a procedure to investigate the occurrence, character and causes of magnetic resonance (MR) imaging incidents. Methods: A semi-structured questionnaire was developed containing details such as safety zones, examination complexity, staff MR knowledge, staff categories, and implementation of EU directive 2013/35. We focused on formally reported inc

Time dependent reduced density matrix functional theory at strong correlation : Insights from a two-site Anderson impurity model

The one-body density matrix has recently attracted considerable attention as a promising key quantity for the description of systems out of equilibrium. Its time evolution is given in terms of the two-body density matrix, and thus the central challenge is to find approximations to the latter. An extra layer of difficulty is added when dealing with strong electron correlations. In this work, we exp

Climate vs. Human Impact : Quantitative and Qualitative Assessment of Streamflow Variation

This paper presents a novel framework comprising analytical, hydrological, and remote sensing techniques to separate the impacts of climate variation and regional human activities on streamflow changes in the Karkheh River basin (KRB) of western Iran. To investigate the type of streamflow changes, the recently developed DBEST algorithm was used to provide a better view of the underlying reasons. T