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Comparison of Normal and Metaplastic Epithelium in Patients with Stable versus Persistently Symptomatic Severe Asthma Using Laser-Capture Microdissection and Data-Independent Acquisition–Mass Spectrometry

A proportion of patients with severe asthma (SA) show poor responses to traditional asthma medications; however, it remains unknown why some patients remain persistently symptomatic. Our objective was to explore the use of laser-capture microdissection of specific epithelial structures combined with quantitative data-independent acquisition mass spectrometry to elucidate differences in protein com

Spatial vision and visually guided behavior in apidae

The family Apidae, which is amongst the largest bee families, are important pollinators globally and have been well studied for their visual adaptations and visually guided behaviors. This review is a synthesis of what is known about their eyes and visual capabilities. There are many species-specific differences, however, the relationship between body size, eye size, resolution, and sensitivity sh

Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

The blood-brain barrier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signaling molecules influence permeability is incompletely understood. We here examined how the apolipoprotein M (apoM)-bound sphingosine 1-phosphate (S1P) signaling pathway affects the BBB in different categories of cerebral microvessels using ApoM deficient mice (Apom-/-). We used t

Imitation as vehicle – and memory as hindrance

What is the relationship between identity, representation and memory in contemporary performance practices? Does memory function as a basic tool in artist’s work or can it also be regarded as a hindrance?In current performance art, identity is often defined as an accumulation of one’s embodied experience and memory. The artist’s body can be seen as an archive which is re-enacted in the encounter w

African Economic Growth 1900-50: Historical National Accounts for British Colonial Africa

The study of growth in African economies during the 20th Century is hampered by the lack of historical GDP estimates. There has been some backward projections, and country case studies, but despite the available data historical national accounts has not yet been assembled. This paper provides GDP estimates for some former British colonies between 1900 – 1950. The estimates indicate faster growth a

Multiscale eigenfrequency optimization of multimaterial lattice structures based on the asymptotic homogenization method

Ultralight lattice structures exhibit excellent mechanical performance and have been used widely. In structural design, the fundamental frequency is highly important. Therefore, a multiscale topology optimization method was utilized to optimize the fundamental frequency of multimaterial lattice structures in this study. Two types of optimization problems were studied, namely, maximizing the natura

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Between 1908 and 1940, 431 young girls between 16 and 21 years of age were enrolled at Vejstrup Re-education Home for Girls. Through close readings of individual case records and other archival material from Vejstrup Re-education Home, this PhD thesis explores the ways in which the so-called “particularly difficult young girls” were perceived as problematic and how they were handled from 1908 to 1

Characterization of hippocampal subfields using ex vivo MRI and histology data : Lessons for in vivo segmentation

Hippocampal subfield segmentation on in vivo MRI is of great interest for cognition, aging, and disease research. Extant subfield segmentation protocols have been based on neuroanatomical references, but these references often give limited information on anatomical variability. Moreover, there is generally a mismatch between the orientation of the histological sections and the often anisotropic co

Determining the Predominant Lesion in Patients With Severe Aortic Stenosis and Coronary Stenoses : A Multicenter Study Using Intracoronary Pressure and Flow

BACKGROUND: Patients with severe aortic stenosis (AS) often have coronary artery disease. Both the aortic valve and the coronary disease influence the blood flow to the myocardium and its ability to respond to stress; leading to exertional symptoms. In this study, we aim to quantify the effect of severe AS on the coronary microcirculation and determine if this is influenced by any concomitant coro

Performing the Other : Report on workshops on Copying and Imitating

Performing The Other. Report on workshops on observing and imitatingThe lecture will present the experience, results and challenges arising within a series of workshops that were investigating the role of observation, copying and imitation in the actor’s work, activities close to Brecht’s aesthetic focus. Claiming that “people will observe you, in order to investigate how well you have observed”,