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Contrast-enhanced magnetic resonance angiography.

Contrast-enhanced magnetic resonance angiography (CE-MRA) is a diagnostic method for imaging of vascular structures based on nuclear magnetic resonance. Vascular enhancement is achieved by injection of a contrast medium (CM). Studies were performed using two different types of CM: conventional paramagnetic CM, and a new type of CM based on hyperpolarized (HP) nuclei. The effects of varying CM con

Treatment of hyperthyroidism: effects on hepatic lipase, lipoprotein lipase, LCAT and plasma lipoproteins

The activities of hepatic lipase and of lipoprotein lipase, the elimination rate of exogenous triglyceride and the cholesterol esterification rate were determined and related to plasma lipoprotein concentrations in 16 patients before and after treatment for hyperthyroidism. The activity of hepatic lipase was significantly higher (65%) before than after treatment, while the activity of lipoprotein

NANC transmitters in the female pig urethra--localization and modulation of release via alpha 2-adrenoceptors and potassium channels

1. To investigate further the release, localization and identity of a non-nitrergic mediator of smooth muscle relaxation in the female pig urethra, we studied the effects of drugs acting at alpha 2-adrenoceptors or K+ channels, the effects of capsaicin and chemical sympathectomy, and the actions of several transmitter candidates. 2. Electrical field stimulation (EFS; frequencies above 12 Hz) of sp

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Popular Abstract in Swedish Den här avhandlingen sätter forskningen om hettitiska ritualer in i en bredare kontext av historisk religionsantropologi. Med sin teoretiska bas i Pierre Bourdieus praxisteori undersöker den dels hur diskursen om hettitiska ritualer och religion har förts inom hettitologi och religionshistoria, dels hur en alternativ diskurs om de så kallade ”besvärjelseritualer” kan föThis thesis deals with the recent discourse about Hittite ritual and religion and assumes an alternative approach. It analyses how the most important researchers in the fields of Hittitology and History of Religions, who have been working with Hittite rituals and religion, describe and explain the rituals. Their implicit or explicit theories underlying the discourse are explored. The restraining e

Tobacco and myocardial infarction in middle-aged women: a study of factors modifying the risk.

Background. Although myocardial infarction (MI) is strongly related to smoking, few have studied why some smokers are more vulnerable than others. This study explored how the risk of MI in current and former smokers is modified by other cardiovascular risk factors. Methods. Incidence of MI (fatal and nonfatal) amongst 10619 women, 48.3 ± 8.2 years old, were studied in relation to smoking, hyperte

The surface oxide as a source of oxygen on Rh(111)

The reduction of a thin surface oxide on the Rh(1 1 1) surface by CO is studied in situ by photoemission spectroscopy, scanning tunneling microscopy, and density functional theory. CO molecules are found not to adsorb on the surface oxide at a sample temperature of 100 K, in contrast to on the clean and chemisorbed oxygen covered surface. Despite this behavior, the surface oxide may still be reduc

COX-2 and SCD, markers of inflammation and adipogenesis, are related to disease activity in Graves' ophthalmopathy

Context: Inflammation and adipogenesis are two parallel processes with increased activity in severe Graves' ophthalmopathy. Objective: The aim of this work was to define target genes for therapeutic intervention in adipogenesis and inflammation in Graves' ophthalmopathy. Design: Orbital tissue was obtained from patients with ophthalmopathy in acute or chronic phase undergoing orbital surgery to st

Rapid and effective CD3 T-cell depletion with a magnetic cell sorting program to produce peripheral blood progenitor cell products for haploidentical transplantation in children and adults.

BACKGROUND: Effective T-cell depletion is a prerequisite for haploidentical peripheral blood progenitor cell (PBPC) transplantation. This study was performed to investigate the performance of magnetic cell sorting–based direct large-scale T-cell depletion, which is an attractive alternative to standard PBPC enrichment procedures. STUDY DESIGN AND METHODS: PBPCs were harvested from 11 human leukoc

Genet age in marginal populations of two clonal Carex species in the Siberian Arctic

During a Swedish-Russian expedition to northern Siberia 1994, we sampled two marginal populations of two Carex species at two high arctic sites (C. stuns Drej. on Faddeyevsky Island and C. ensifolia V. Krecz ssp, arctisibirica Jurtz. at north-eastern Taymyr Peninsula), both north of previously documented localities in that areas for the two species. These populations were composed of a few distinc

Integrated selective enrichment target (ISET) - A generic microfabricated sample preparation device

A combined sample preparation and sample presentation device, Integrated Selective Enrichment Target (ISET), consisting of an array with 96 perforated nanovials is described. Each perforated nanovial can be filled with soild-phase extraction media for purification and concentration of biomolecules prior to mass spectrometry. The ISET platform provides an efficient, economic and generic sample trea

Actin redistribution underlies the sparing effect of mild hypothermia on dendritic spine morphology after in vitro ischemia.

Brain hypothermia is at present the most effective neuroprotective treatment against brain ischemia in man. Ischemia induces a redistribution of proteins involved in synaptic functions, which is markedly diminished by therapeutic hypothermia (33 degrees C). Dendritic spines at excitatory synapses are motile and show both shape changes and rearrangement of synaptic proteins as a consequence of neur

Kritisk analys av skattningar av samhällets kostnader för alkoholkonsumtion – en diskussion om fem studiers metodval och resultat

The consumption of alcohol imposes costs on the society and several cost-of-illness studies have been conducted to estimate these costs. This essay presents the results from five cost-of-illness studies and examines the methodology used. The differences in results are discussed in reference to the differences in the applied methods. The results differ immensely from US$ 91 to US$ 2,433 per capita.

Uniform molecularly imprinted microspheres and nanoparticles prepared by precipitation polymerization: The control of particle size suitable for different analytical applications

Molecularly imprinted polymers (MIPs) are being increasingly used as selective adsorbents in different analytical applications. To satisfy the different application purposes, MEN with well controlled physical forms in different size ranges are highly desirable. For examples, MIP nanoparticles are very suitable to be used to develop binding assays and for microfluidic separations, whereas MIP beads

»Grundad teori« utvecklar läkekonsten. Populär beteendevetenskaplig forskningsmetod kan finna nya samband

Grounded theory (GT) is a popular research method for exploring human behavior. GT was developed by the medical sociologists Glaser and Strauss while they studied dying in hospitals in the 1960s resulting in the book "Awareness of dying". The goal of a GT is to generate conceptual theories by using all types of data but without applying existing theories and hypotheses. GT procedures are mostly in