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Visualization of the melanosome transfer-inhibition in a mouse epidermal cell co-culture model.

Transfer of melanin-containing melanosomes from melanocytes to neighboring keratinocytes results in skin pigmentation. To provide a more practical method of visualizing melanosomes in melanocytes as well as in keratinocytes, we attempted to use murine cell lines instead of human primary cells. We generated various fluorescent fusion proteins of tyrosinase, a melanin synthesis enzyme located in the

Maktdimensionen i omsorgsrelationer

Bakgrund: Vårdbiträdet och den äldre formar tillsammans en dynamik i sitt sociala samspel. Här presenteras resultat från en avhandling om omsorgsrelationer i hemtjänsten. Metod: Djupintervjuer av äldre och vårdbiträden; fallstudier kring biståndsärenden med hjälp av deltagande observation av den äldres och vårdbiträdets samspel samt av samspelet i vårdbiträdets arbetsgrupp. Resultat: Det är van

The Service Oriented Business Process and Separation of Concerns - Modelling paradigms for Architectures and Business Processes

This paper deals with the contemporary concern of business service-orientation. The paper suggests that service-oriented Business Information Systems Development (BISD) permits quality aspects, -“ilities” e.g.; maintainability and modifiability, of BISs and BISD. In addition, this paper departs from viewing a Business Information System (BIS) as services and suggests Separation of Concerns (SoC) a

Endovascular Aneurysm Repair: Current and Future Status.

Endovascular aneurysm repair has rapidly expanded since its introduction in the early 1990s. Early experiences were associated with high rates of complications including conversion to open repair. Perioperative morbidity and mortality results have improved but these concerns have been replaced by questions about long-term durability. Gradually, too, these problems have been addressed. Challenges o

Is the Vienna Convention Hostile to Drafting History: A Response to Julian Davis Mortenson

Julian D. Mortenson has written an article for the most recent issue of the American Journal of International Law which he has furnished with the title "The Travaux of Travaux: Is the Vienna Convention Hostile to Drafting History?" The article suggests a reading of Articles 31 and 32 of the 1969 Vienna Convention on the Law of Treaties that is radically different from the one generally assumed. As