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The Contractualization of Human Rights - State-Investor Contracts in the Agri-Business Sector

An increase in large-scale agricultural investment in land has been going on since the global food crisis in 2008. Import-dependent countries have acquired large plots of land to secure food supplies. The investments had disastrous impacts on the local communities living on the land before the investment took place. Many have been expropriated and evicted from their lands, affecting their human ri

System design of a DC based micro grid - A comparison study on the Andaman Islands

The world today stands at a cross roads when it comes to energy and electrical grids. A large part of the worlds population still lacks access to reliable working electricity 24 hours a day. Much of this is in remote and poor parts of the world. For much of the 20th century large centralized AC grids have been the norm to provide people with electricity. But for remote parts of the world including

Effects of ω-3 and ω-6 fatty acids

Abstract: The importance of dietary fatty acids (FAs), in particular omega-3 and omega-6 polyunsaturated (PUFAs), for immune system functions has been recognised and well-studied in mammals over the last decades. Recent studies suggest that similar positive/negative (e.g. strengthened/weakened immune com-petence) effects can be present in avian species. In this study, I explored these effects of ω

Det utsatta subjektet - Den separatistiska diskursen på Makthavarna

Framväxten av separatistiska organisationer för rasifierade i Sverige har periodvis erhållit stor uppmärksamhet. Förespråkarna ser det som ett sätt för strukturellt underordnade att stärka varandra, medan belackarna ser det som begränsande och destruktivt. Förståelsen för hur diskursiva praktiker struktureras inom separatistiska rörelser är emellertid begränsad. I denna studie har en diskursanalys

Little flying microalgae, who are you? - Taxonomy determination of airborne microalgae monocultures

Små flygande mikroalger – vilka är ni? Mikroalger är små encelliga fotosyntetiska mikroorganismer (1–500 μm i diameter), knappt synliga för ögat. De finns precis överallt omkring oss, i luften vi andas, i vattnet vi dricker och på våra husväggar. Det är inte mycket vi vet om dessa små mikroorganismer. Några av dem är luftburna, vilket innebär att de kan sprida sig långa sträckor med vindpustar fr

The role of galectin-3 in regulating microglia inflammation in Alzheimer’s disease

Brain Inflammation in Alzheimer’s disease Nowadays, Alzheimer’s disease (AD) is the main cause of dementia worldwide but still is not well understood how is the disease developed. However, there are few known factors that are important in the progression of the disease. In the last decade, the role of the inflammatory cells has been clearly link to the pathology. Hence, the aim of our project is

The effect of glucolipotox treatment on DNA methylation, gene expression, and cellular function in human pancreatic islets

Aims/hypothesis The aims of this project was to investigate the effect of glucolipotoxic treatment on DNA methylation and gene expression patterns in pancreatic islets and functionally test if and how these changes alter insulin secretion. Methods Genome-wide mRNA expression and DNA methylation patterns were analyzed in human pancreatic islets after control or glucolipotoxic treatment. Alterations

Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

Hur kan cellers försvarsmekanismer hjälpa oss förstå Parkinsons sjukdom? Parkinsons sjukdom är den andra mest vanliga neurodegenerativa sjukdomen i världen, och under sjukdomens gång dör allt fler hjärnceller vilket leder till svårigheter för hjärnan. När fler och fler celler försvinner, får hjärnan problem att kontrollera de signaler som den skickar ut till kroppen, vilket leder till symptom somParkinson’s disease (PD) is a movement disorder of the brain which is hallmarked by the presence of large protein-rich cytoplasmic aggregates, called Lewy bodies (LBs), in the neurons. The protein α-synuclein (α-syn) is abundant in these aggregates, and can itself form aggregates. Several mutations linked to α-syn are also linked to an increased risk of contracting PD. In healthy neurons, the chap

The Search Continues -Problems of finding a consistent performance measure for Hedge Funds

The question of whether the choice of performance measure (PM) matters when evaluating Hedge funds has for a long time been subject to debate . This study explores the same question with a sample of individual monthly data from 669 Hedge Funds over a 10 year period. The standard rank correlation tests usually applied when studying the topic yield weaker correlations between the PM:s in our study t

Risk-Managed Momentum in Europe

This thesis sets out to evaluate a risk-managed momentum strategy in the European stock market. The recent performance of momentum in Europe is first evaluated. A momentum premium still exists in Europe but the strategy suffered large losses in 2009. A risk-managed momentum portfolio is created by dynamically scaling the exposure to momentum based on a monthly volatility forecast. The risk-managed

Pro-inflammatory cytokine regulation by the immunomodulatory protein p33

p33 as a potential novel therapeutic target in inflammatory diseases Inflammation is a condition usually triggered by infection of invading pathogens such as bacteria or viruses in the body. This invasion is quickly recognized by specific receptors localized on the membrane of cells, ready to sense these so called “danger” signals or foreign material. These receptors are part of the innate immuni

Transgender Individuals’ Thoughts and Experiences Regarding the Transition Process: An Interpretative Phenomenological Analysis

This study utilizes Interpretative Phenomenological Analysis (IPA) to gain an in-depth understanding of transgender individuals’ transition experiences and thoughts regarding the diagnostic classification of Gender Dysphoria issued by the Diagnostic and Statistical Manual of Mental Disorders (DSM) and Transsexualism issued by the International Classification of Diseases (ICD). The study focused up

Postprandial Effects of Mixed Spices on Peripheral Blood Mononuclear Cells (PBMC’s) Gene Expressions associated with Lipid Metabolism and Inflammatory Responses in Humans: A Randomized Crossover Study

Cooking with culinary spices shows health benefits Every time we eat a meal, our body will turn into a post-meal state and face a lot of challenges induced by the food intake. These challenges include blood glucose spikes, triggered inflammation and increased total cholesterol concentrations. If these challenges happen too many times a day and reach an abnormal level, then there is a risk of deve

Functional study of domains of class B penicillin-binding proteins 4b and SpoVD in Bacillus subtilis

How are penicillin-binding proteins sorted in cells? A bacterial cell wall can be regarded as a brick building, in which the bricks and the cement hold the building together, provide structure for the building, protect its contents, and allow only certain substances to enter. Many antibiotics target proteins that function in cell wall morphogenesis (the process of building the brick wall in this

Mycobacterium marinum promotes mitochondrial degradation in an ESX-1 dependent manner

Investigating the role of mitochondrial damage in a Tuberculosis infection Tuberculosis (TB) is a significant health risk that was responsible for 10.4 million infections and 1.8 million deaths in the year 2015 alone. The causative agent for TB is Mycobacterium tuberculosis (Mtb), which is an intra-cellular bacterium that primarily replicates within the white blood cell called the macrophage. To

Från ett nytt perspektiv - En kvalitativ studie om influencer marketing från en influencers perspektiv

Från ett nytt perspektiv Influencer marketing beskriver marknadsföringstekniken då företag använder inflytelserika och kända personer för att effektivt sprida ett budskap. Inom influencer marketing verkar de budskapspridande individerna, influencers, på de digitala plattformar som kallas sociala medier, däribland forum som Instagram, Facebook och Snapchat. Inom influencer marketing finns två parteFrom a new perspective Influencer Marketing describes a marketing technique where companies are using influential and well-known people to effectively spread a message. Through influencer marketing the message-spreading individuals, influencers, appear on the digital platforms known as social media, including forums such as Instagram, Facebook and Snapchat. Within influencer marketing there are tw

Separation and Extraction of Proteins and Polysaccharides from the Seaweed Palmaria Palmata using Enzyme Digestion

Vetenskapliga artiklar föreslår att xylan är delvis bundet till proteinerna i dulse. Detta kan leda till minskad tillgänglighet av proteinerna och leda till svårigheter att smälta dessa i tarmen. Denna rapport har för avsikt att hitta och optimera metoder för extraktion av proteiner och metoder för att separera de proteiner och polysackarider som förekommer i dulse. Metoderna som används är hydrolSeaweed has a great potential within human food and animal feed industry. Palmaria palmata (P. palmata) or more commonly dulse, is a type of red seaweed which has a high protein content (8-35%), rich in minerals such as iodine and iron and contain high levels of dietary fibers. The main polysaccharide in dulse is xylan. It has been suggested that the xylans are linked to the proteins in the seawee

Scanning probe microscopy with gallium nitride nanowires

In scanning probe microscopy the properties of the tip is crucial in determining which information that can be obtained from the resulting images and spectroscopy. Ordinarily metal tips are used for scanning, however by using semiconducting nanowires as tips one would have very well defined probes with more advanced possibilities for spectroscopic measurements. However, currently creating such hig

Mutation tolerance in cell models with manipulated osteosarcoma-genes

Vilket protein vaktar arvsmassan bäst? Osteosarkoma är den mest förekommande elakartade bentumören. Den drabbar unga under 25 år och framförallt när de når puberteten. Tekniska framsteg och aggressiv behandling inom tumörsjukdomar har gjort att vi idag har en förväntad överlevnad på ungefär 60-70 % , en siffra som kan och måste förbättras. Det är viktigt att forskningen trappas upp så att alla ba

Samma sjukvård i hela riket? En jämförelse av överlevnad vid behandling av allvarliga sjukdomar.

Syftet med rapporten är att undersöka om det finns statistiskt signifikanta skillnader för fyra sjukdomstyper mellan de 21 landstingen i Sverige. I Sverige eftersträvas vård på lika villkor, detta är däremot svårt att åstadkomma. För att kunna redogöra skillnader mellan landstingen måste det tas hänsyn till 'case-mix'. Detta betyder att de olika landstingen inkludera ett olikt antal patien