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Solitons, vortices and shell structure in ultracold atomic quantum systems

This dissertation deals with finite-size effects in a few different quantum many-body phenomena in ultracold atomic systems. The finite-sized systems were simulated numerically using both mean-field methods and methods beyond mean-field, e.g. quadratic configuration interaction and exact diagonalization. The thesis is based on five scientific papers:Paper I is about the finite-size effects in the

Impact of Changes to the Atmospheric Soluble Iron Deposition Flux on Ocean Biogeochemical Cycles in the Anthropocene

Iron can be a growth‐limiting nutrient for phytoplankton, modifying rates of net primary production, nitrogen fixation, and carbon export ‐ highlighting the importance of new iron inputs from the atmosphere. The bioavailable iron fraction depends on the emission source and the dissolution during transport. The impacts of anthropogenic combustion and land use change on emissions from industrial, do

Antisecretory Factor May Reduce ICP in Severe TBI—A Case Series

Traumatic brain injury (TBI) constitutes a global epidemic. Overall outcome is poor, with mortality ranging from 10 to 70% and significant long-term morbidity. Several experimental reports have claimed effect on traumatic edema, but all clinical trials have failed. Antisecretory factor, an endogenous protein, is commercially available as Salovum®, which is classified as a medical food by the Europ

Hyperdigitalisering, övervakning och pandemiappar i Corona-krisens spår

Under Corona-krisen har digitaliseringen på vissa områden forcerats fram. Vi har intervjuat Stefan Larsson, docent i teknik och social förändring om digitaliseringens och plattformarnas roll, pandemiappar och hur vi kan förstå datainsamling och integritetsskyddsfrågor i relation till krisen.

A process for identifying national solutions to challenges faced in developing countries in reporting to environmental conventions : Insight from the facilitating national reporting to the rio conventions project

Almost all countries in the world are party to the Rio Conventions. This entails a number of responsibilities, including reporting periodically on aspects of environmental health and national implementation of the convention. These reports can cover hundreds of pages, so completing reports is often a significant undertaking. Since countries can be party to numerous Multilateral Environmental Agree

Synthesis of Cr(III) Salen Complexes as Supramolecular Catalytic Systems for Ring-Opening Reactions of Epoxides

The synthesis of two conformationally restricted Cr(III) salen complexes, 2 and 3, is described. Together, they constitute a supramolecular hydrogen-bonding catalytic system for the recently reported asymmetric ring-opening reactions of epoxides by a dynamic supramolecular catalyst. The synthesis involves state-of-the art transformations in frontline synthetic chemistry applied to heterocyclic che

Detection of Bax Microsatellite Mutations and BaxΔ2 Isoform in Human Buccal Cells

Loss of the pro-apoptotic Bcl-2 family protein Bax occurs in ~50% of hereditary nonpolyposis colorectal cancer (HNPCC) due to microsatellite instability (MSI). Recently, we found that some of the "Bax-negative" MSI tumor cells contain a functional Bax isoform, BaxΔ2, which sensitizes cells to selective chemotherapeutics. Here we show the detection of Bax microsatellite mutations and expression of

Parental cooperation in a changing climate : fluctuating environments predict shifts in care division

Aim: Parental care improves the survival of offspring and therefore has a major impact on reproductive success. It is increasingly recognized that coordinated biparental care is necessary to ensure the survival of offspring in hostile environments, but little is known about the influence of environmental fluctuations on parental cooperation. Assessing the impacts of environmental stochasticity, ho

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

We performed a genome-wide association study of total hip replacements, based on variants identified through whole-genome sequencing, which included 4,657 Icelandic patients and 207,514 population controls. We discovered two rare signals that strongly associate with osteoarthritis total hip replacement: a missense variant, c.1141G>C (p.Asp369His), in the COMP gene (allelic frequency = 0.026%, P =

Groundwater contamination risks from conservative point source pollutants in a future climate

The groundwater contamination risk in future climates was investigated at three locations in Sweden. Solute transport penetration depths were simulated using the HYDRUS-1D model using historical data and an ensemble of climate projections including two global climate models (GCMs), three emission scenarios and one regional climate model. Most projections indicated increasing precipitation and evap

Smartphones and Newton's first law in escalators and roller coasters

Your body is not a point particle. The nature and direction of the forces counteracting gravity influence your experience of uniform rectilinear motion- A s does your own orientation in relation to the force of gravity. Sensors in smartphones or other devices can capture these forces, and help establish a connection between the personal experience of motion and the textbook description of forces a

Cellular and molecular mechanisms in immune mediated hepatic fibrosis. A study of the inflammatory syndrome and fibrosis development of the NIF mouse liver.

Fibrosis is the result of dysregulated inflammation and tissue repair, and is characterized by the excessive accumulation of extra cellular matrix (ECM) proteins. It causes detrimental effects to the afflicted tissue and can subsequently lead to organ failure. Sterile liver inflammation and hepatic fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 in