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EANM practical guidance on uncertainty analysis for molecular radiotherapy absorbed dose calculations

A framework is proposed for modelling the uncertainty in the measurement processes constituting the dosimetry chain that are involved in internal absorbed dose calculations. The starting point is the basic model for absorbed dose in a site of interest as the product of the cumulated activity and a dose factor. In turn, the cumulated activity is given by the area under a time–activity curve derived

Prevalence and Clinical Relevance of Extracardiac Findings in Cardiovascular Magnetic Resonance Imaging

Purpose: To assess the prevalence of extracardiac findings (ECF) during cardiovascular magnetic resonance (CMR) examinations and their downstream effect on clinical management. Materials and Methods: We retrospectively identified 500 consecutive patients. Trans-axial balanced steady-state free precession nongated images acquired from the upper thorax to the upper abdomen were evaluated independent

Missbruk av heroin och andra opioider

Denna bok bygger på aktuell forskning om opioidmissbruk i dess olika former och om lösningar för personer som fastnat i ett opioidmissbruk. Utifrån forskningen besvarar vi frågor som: Varför börjar unga människor använda dessa preparat? Varför är det så svårt att sluta när man har blivit beroende av opioider? Hur ser framgångsrik behandling ut?Under de senaste tjugo åren har olika opioidpreparat s

Cognitive deficits and psychopathological symptoms among children with medulloblastoma

Children with medulloblastoma (MB) are predisposed for negative cognitive sequela, which has been widely identified in this population. The purpose of the present study was to explore cognitive deficits and psychopathological symptoms and analyse their relation among MB survivors. The Wechsler Intelligence Scale for Children and the Mini International Neuropsychiatric Interview (MINI-KID) was admi

Ischemic QRS prolongation as a predictor of ventricular fibrillation in a canine model

Objectives. An acute coronary occlusion and its possible subsequent complications is one of the most common causes of death. One such complication is ventricular fibrillation (VF) due to myocardial ischemia. The severity of ischemia is related to the amount of coronary arterial collateral flow. In dog studies collateral flow has also been shown to be associated with QRS prolongation. The aim of th

LED and Life Cycles : Life Cycle Environmental Concerns in Procurement of LED Light

The development of LED light has been rapid in the last decade and it has become the most attractive lighting solution for many buyers. The reasons have to do with the high energy efficiency of these lamps as compared to the traditional incandescent lamps. As society is trying to cope with climate change threats and all the connected issues related to nature and life of people, all opportunities t

LED och livscykler : Livscykelbaserade miljöhänsyn vid inköp av LED-ljus

LED-ljusen har utvecklats i snabb takt under de senaste tio åren och de är idag de ljus som är mest attraktiva för många köpare. Det som gör dem så attraktiva är främst deras höga energieffektivitet jämfört med traditionella glödlampor. I linje med hur vi försöker handskas med klimatförändringarna och alla de hotbilder för människor och natur som denna utveckling förknippas med, så behöver vi ta t

Evaluation of atomic layer etching possibility at Lund Nano Lab

In modern electronics, device downscaling demands atomic precision control and Atomic Layer Etching (ALE) can provide this prime capability with minute device damage. ALE, also known as layer-by-layer etching, is a technique of removing atomically thin layers from the surface of materials in a controlled way.This technique is now very crucial for nanofabrication and semiconductor industry in order

Jesus the True Leader : The Biographical Portrait of Jesus as Leader in the Gospel of Matthew

The purpose of the present study is to understand and clarify how Jesus is presented as a leader in the Gospel of Matthew. The usage of common leadership terms in reference to Jesus early in the story, the biographical genre of Matthew, and the consistently negative portrayal of other leaders in the story give good reasons for the inquiry. Three main questions are at the forefront: How does the th

Hand eczema and occupational contact allergies in healthcare workers with a focus on rubber additives

Background: Hand eczema (HE) in healthcare workers (HCWs) is common. Besides wet work, healthcare work also implies exposure to contact allergens. Objectives: To assess HE and contact allergy related to occupational exposures in HCWs. Methods: In a cross-sectional study, 311 HCWs with HE within the preceding 12 months and a control group of 114 HCWs without HE were investigated with the baseline s

Developing and sustaining new regional industrial paths : investigating the role of ‘outsiders’ and factors shaping long-term trajectories

This article casts light on the development of new regional industrial paths. We explore factors explaining why regional industries with similar early path development trajectories may exhibit diverging outcomes in the longer run and pay particular attention to the role of ‘outsiders’ in the initiation and further development of regional industrial paths. Drawing on a comparative case study of IT

Favorable effect of mycorrhizae on biomass production efficiency exceeds their carbon cost in a fertilization experiment

Biomass production efficiency (BPE), the ratio of biomass production to photosynthesis, varies greatly among ecosystems and typically increases with increasing nutrient availability. Reduced carbon partitioning to mycorrhizal fungi (i.e., per unit photosynthesis) is the hypothesized underlying mechanism, as mycorrhizal abundance and plant dependence on these symbionts typically decrease with incre

Human Neural Stem Cells for Ischemic Stroke Treatment

Ischemic stroke is the second most common cause of death worldwide and a major cause of disability. It takes place when the brain does not receive sufficient blood supply due to the blood clot in the vessels or narrowing of vessels’ inner space due to accumulation of fat products. Apart from thrombolysis (dissolving of blood clot) and thrombectomy (surgical removal of blood clot or widening of ves

Direct observation of aliphatic structures in soot particles produced in low-pressure premixed ethylene flames via online Raman spectroscopy

Raman spectra of soot particles were monitored in the gaseous flow extracted from the burning regions of two low-pressure premixed ethylene flames, for the first time. The flame conditions were chosen to explore the diversity of soot nanostructure in slightly sooting flames. Evaluation of the Raman spectral parameters revealed that the soot particles exhibited a strongly disordered structure and a

On the choice of turbine type for a twin-turbine heavy-duty turbocharger concept

In this study, a fundamental approach to the choice of turbocharger turbine for a pulse-charged heavy-duty diesel engine is presented. A standard six-cylinder engine build with a production exhaust manifold and a Twin-scroll turbocharger is used as a baseline case. The engine exhaust configuration is redesigned and evaluated in engine simulations for a pulse-charged concept consisting of a paralle

Public health nurses’ experiences of using interpreters when meeting with Arabic-speaking first-time mothers

Objectives: The aim of this study was to investigate public health nurses’ experiences of using interpreters when meeting with Arabic-speaking first-time mothers. Design and Sample: An inductive qualitative design was used. Individual interviews were conducted with Swedish public health nurses (n = 11) with experience of working in child health care with interpreters when meeting with Arabic-speak

GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression

The ETS family transcription factor GABPA is suggested as an oncogenic element, which is further supported by the recent reporting of it as the sole ETS member to activate the mutant TERT promoter in thyroid carcinomas (TC). However, it remains unclear how GABPA contributes to TC pathogenesis. The present study is designed to address this issue. TERT expression was significantly diminished in TERT

Investigating the Onset of Strain Localization Within Anisotropic Shale Using Digital Volume Correlation of Time-Resolved X-Ray Microtomography Images

Digital volume correlation analysis of time-resolved X-ray microtomography scans acquired during in situ triaxial compression of Green River shale cores provided time series of 3-D incremental strain fields that elucidated evolving deformation processes by quantifying microscopic strain localization. With these data, we investigated the impact of mechanical anisotropy on microscopic strain localiz