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The development of supply chain risk management over time : revisiting Ericsson

Purpose: This invited article explores current developments in supply chain risk management (SCRM) practices by revisiting the classical case of Ericsson (Norrman and Jansson, 2004) after 15 years, and updating its case description and analysis of its organizational structure, processes and tools for SCRM. Design/methodology/approach: An exploratory case study is conducted with a longitudinal focu

Informed successive condition assessments in bridge maintenance

The condition assessment of bridges considers a combination of information from different sources rendering multiple levels of assessment possible. This paper illustrates how successive condition assessment strategies increase the expected utility compared to single choice decisions through Bayesian inference. Multiple levels of assessment allow for additional possibilities for obtaining structura

Brush Tire Model with increased Flexibility

This article covers a method to make the description of theforce-slip curve generated by the brush tire model more flexible. A calibration factor is applied to make the slope more or less convex. The main use is in car applications where road friction estimation is a major issue. If the real tire characteristic differs from the model there will be a bias in the estimation and a higher brake force

Highly efficient energy transfer from a water soluble zinc silver indium sulphide quantum dot to organic J-aggregates

The present work has been carried out with the aim to design and develop an efficient light harvesting inorganic-organic hybrid nanoscale material by employing a less toxic, environment friendly inorganic substance and also to understand the mechanism of inter-particle electronic interaction between the inorganic and organic components of the nanomaterial. Specifically, the inorganic-organic hybri

The HIV care continuum and HIV-1 drug resistance among female sex workers : a key population in Guinea-Bissau

INTRODUCTION: Female sex workers (FSW) are considered a key group for HIV transmissions in sub-Saharan Africa. The HIV Care Continuum and HIV drug resistance (HIVDR) among FSW has not been well studied in most countries in West Africa. In the current study we describe the HIV Care continuum and prevalence of HIVDR among FSW in Guinea-Bissau. METHODS: A venue-based recruitment and peer-referral of

Anisotropic dynamics of a self-assembled colloidal chain in an active bath

Anisotropic macromolecules exposed to non-equilibrium (active) noise are very common in biological systems, and an accurate understanding of their anisotropic dynamics is therefore crucial. Here, we experimentally investigate the dynamics of isolated chains assembled from magnetic microparticles at a liquid-air interface and moving in an active bath consisting of motile E. coli bacteria. We invest

Shiga Toxin Uptake and Sequestration in Extracellular Vesicles Is Mediated by Its B-Subunit

Shiga toxin (Stx)-stimulated blood cells shed extracellular vesicles (EVs) which can transfer the toxin to the kidneys and lead to hemolytic uremic syndrome. The toxin can be taken up by renal cells within EVs wherein the toxin is released, ultimately leading to cell death. The mechanism by which Stx is taken up, translocated, and sequestered in EVs was addressed in this study utilizing the B-subu

Förändringar i antal och lokal utbredning hos övervintrande sjöfåglar vid den skånska sydkusten under 55 vintrar, 1964–2018

THE SOUTH COAST of Scania, southernmost Sweden, has long been an important wintering and staging area for waterbirds. A large part of the coast was surveyed annually as a part of the international midwinter counts for 55 years (1964–2018). The total number of wintering waterbirds showed an increasing trend but there was much variation between years. Common Goldeneye Bucephala clangula, followed by

The association between habitual sleep duration and mortality according to sex and age : the Japan Public Health Center-based Prospective Study

BackgroundShort and long sleep durations are associated with mortality outcomes. The association between sleep duration and mortality outcomes may differ according to sex and age.MethodsParticipants of the Japan Public Health Center-based prospective study (JPHC Study) were aged 40-69 years and had completed a detailed questionnaire on lifestyle factors. Sex- and age-stratified analyses on the ass

A nonrandomized open-label phase 2 trial of nonischemic heart preservation for human heart transplantation

Pre-clinical heart transplantation studies have shown that ex vivo non-ischemic heart preservation (NIHP) can be safely used for 24 h. Here we perform a prospective, open-label, non-randomized phase II study comparing NIHP to static cold preservation (SCS), the current standard for adult heart transplantation. All adult recipients on waiting lists for heart transplantation were included in the stu

Temperate insects with narrow seasonal activity periods can be as vulnerable to climate change as tropical insect species

The magnitude and ecological impact of climate change varies with latitude. Several recent models have shown that tropical ectotherms face the greatest risk from warming because they currently experience temperatures much closer to their physiological optimum than temperate taxa. Even a small increase in temperature may thus result in steep fitness declines in tropical species but increased fitnes

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

The study of brain development in humans is limited by the lack of tissue samples and suitable in vitro models. Here, we model early human neural tube development using human embryonic stem cells cultured in a microfluidic device. The approach, named microfluidic-controlled stem cell regionalization (MiSTR), exposes pluripotent stem cells to signaling gradients that mimic developmental patterning.

Combustion LES of a multi-burner annular aero-engine combustor using a skeletal reaction mechanism for jet- a air mixtures

In this study we describe combustion simulations of a single sector and a fully annular generic multi-burner aero-engine combustor. The objectives are to facilitate the understanding of the flow, mixing and combustion processes to help improve the combustor design and the design process, as well as to show that it is now feasible to perform high-fidelity reacting flow simulations of full annular g

Second trimester cervical length measurements with transvaginal ultrasound : A prospective observational agreement and reliability study

Introduction: Universal screening for preterm delivery by adding transvaginal ultrasound measurement of cervical length to routine second trimester ultrasound has been proposed. The aim is to estimate inter- and intraobserver agreement and reliability of second trimester transvaginal ultrasound measurements of cervical length performed by specially trained midwife sonographers. Material and method

Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies

Background: Change in albuminuria as a surrogate endpoint for progression of chronic kidney disease is strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies is lacking. We aimed to assess the consistency of the association between change in albuminuria and risk of end-stage kidney disease in a large individual participant-level met

Can grating interferometry-based mammography discriminate benign from malignant microcalcifications in fresh biopsy samples?

PurposeIn addition to absorption imaging, grating interferometry-based mammography (GIM) is capable of detecting differential-phase and scattering signals. In particular, the scattering signal can enable a quantifiable characterization of breast lesions. The purpose of this study was to determine if suspicious microcalcifications associated with benign or malignant lesions can be discriminated bas

Cerebrospinal fluid levels of GFAP and pNF-H are elevated in patients with chronic spinal cord injury and neurological deterioration

Background: Years after a traumatic spinal cord injury (SCI), a subset of patients may develop progressive clinical deterioration due to intradural scar formation and spinal cord tethering, with or without an associated syringomyelia. Meningitis, intradural hemorrhages, or intradural tumor surgery may also trigger glial scar formation and spinal cord tethering, leading to neurological worsening. S