Background: There is insufficient knowledge available about the impact of paediatric palliative care at home on meeting family needs and ensuring the highest quality of care for the dying child. The aim of this study was to elucidate parents’ experiences of how and why home-based paediatric palliative care impacted the entire family during their child's final phase of life. Methods: The study used

This chapter aims to encourage tourism researchers to widen their scope of method when studying tourist behavior. It does so by debating tracking mobility and planning exercises as meaningful complements in researchers’ method repertoire. Both methods have been found to reflect tourist behavior in a more accurate way than do, for example, surveys and interviews, which rather mirror what tourists s

Among the fundamental problems in canopy turbulence, particularly near the forest floor, remain the local diabatic effects and linkages between turbulent length scales and the canopy morphology. To progress on these problems, mean and higher order turbulence statistics are collected in a uniform pine forest across a wide range of atmospheric stability conditions using five 3-D anemometers in the s

Angiogenesis inhibition is an established treatment for several tumor types. Unfortunately, this therapy is associated with adverse effects, including hypertension and renal toxicity, referred to as "preeclampsia." Recently, we demonstrated in patients and in rats that the multitarget tyrosine kinase inhibitor sunitinib induces a rise in blood pressure (BP), renal dysfunction, and proteinuria asso

IgA nephropathy (IgAN) and Henoch-Schönlein purpura (HSP) are diseases characterized by IgA deposits in the kidney and/or skin. Both may arise after upper respiratory tract infections, but the pathogenic mechanisms governing these diseases remain unclear. Patients with IgAN (n = 16) and HSP (n = 17) were included in this study aimed at examining whether IgA-binding M proteins of group A streptococ

Biochar addition to soils has been proposed as a means to increase soil fertility and carbon sequestration. However, its effect on soil nitrogen (N) cycling and N availability is poorly understood. To gain better insight into the temporal variability of the impact of biochar on gross soil N dynamics, two 15N tracing experiments, in combination with numerical data analysis, were conducted with soil

Epidemiological and animal studies have shown that dietary fiber is protective against the development of colon cancer. Dietary fiber is a rich source of the hydroxycinnamic acids ferulic acid (FA) and p-coumaric acid (p-CA), which both may contribute to the protective effect. We have investigated the effects of FA and p-CA treatment on global gene expression in Caco-2 colon cancer cells. The Caco

AIMS/HYPOTHESIS: Islet autoantibodies are important in diabetes classification and risk assessment, and as endpoints in observational studies. The Diabetes Autoantibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type 1 diabetes. We report results for glutamic acid decarboxylase autoantibodies (GADA) and islet antigen-2 autoantibodie

Deficiency of P and sometimes of micronutrients; especially Fe, is of importance to the calcicole-calcifuge behaviour of plants. Calcifuge species are unable to solubilize these elements or keep them metabolically active in sufficient amounts on calcareous soils. To demonstrate if calcicole, calcifuge and 'soil indifferent' species differ in Fe nutrition dynamics, samples of such species were tran

Purpose. To describe experiences and perceptions of work ability and how it can be assessed among Swedish physicians. Method. We interviewed eight men and six women in the fields of general practice, occupational health, rehabilitation and orthopaedic surgery. Qualitative content analysis was applied to the data. Results. The approach striving to support the patient in mutual confidence was what p

The study of localized deformation in porous sandstones at the laboratory scale can yield valuable insights into the internal structures and mechanisms of shear zones and compaction bands that might impact on flow at a reservoir scale. Herein, we report results of a laboratory study of shear and compaction band formation in a porous sandstone using a range of full-field experimental techniques: ac

The objective of this work was to observe and quantify the onset and evolution of localised deformation processes in sand with grain-scale resolution. The key element of the proposed approach is combining state-of-the-art X-ray micro tomography imaging with three-dimensional volumetric digital image correlation techniques. This allows not only the grain-scale details of a deforming sand specimen t