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Ab initio thermo-elasticity of 𝛿-MH𝑥 (M=Zr, Ti)

In the present work, we report the results of a systematic ab initio study of the thermo-elastic properties of δδMH1.5 (M=Zr, Ti). This investigation serves three purposes: (i) Elucidate the fully anisotropic temperature dependent elastic constants of hydrides, (ii) address discrepancies in thermal expansion data reported in the literature and (iii) provide input data for thermodynamic-based phase

An improved estimation of soil water and salt dynamics by considering soil bulk density changes under freeze/thaw conditions in arid areas with shallow groundwater tables

Soil bulk density (BD) is a parameter dependent on soil texture, compositions of soil minerals and organic matter and the extent of soil compaction. Seasonal freeze/thaw in arid areas with shallow groundwater tables (AASGT) may significantly change BD and hence soil hydrothermal properties and water holding capacity. Therefore, quantifying soil bulk density changes (BDC) under freeze/thaw conditio

A tunable physiomimetic stretch system evaluated with precision cut lung slices and recellularized human lung scaffolds

Breathing exposes lung cells to continual mechanical stimuli, which is part of the microenvironmental signals directing cellular functions together with the extracellular matrix (ECM). Therefore, developing systems that incorporate both stimuli is urgent to fully understand cell behavior. This study aims to introduce a novel in vitro culture methodology combining a cyclic stretch that simulates in

Fatigue trajectories during pediatric ALL therapy are associated with fatigue after treatment: a national longitudinal cohort study

Objective: Fatigue is one of the most prevalent and distressing symptoms reported by survivors of childhood cancer. There is currently a lack of longitudinal studies on cancer-related fatigue, and especially on the relationship between the course of fatigue during treatment and fatigue at follow-up. The purpose of the current study was therefore to investigate if the course of fatigue during treat

Det går att minska D-interaktioner : Interaktioner åtgärdades ofta efter patientspecifika brev till allmänläkare

För att se om antalet D-interaktioner kunde minskas skickades information om interaktioner på individnivå till vårdcentraler.Allmänläkarna ombads att utifrån medföljande rekommendationer ompröva behandlingen och besvara en enkät.Mindre än hälften av D-interaktionerna berodde på medvetna ordinationsval.Mer än hälften av interaktionerna hade uppkommit det senaste året, trots tydlig varning vid ordinDuring 2012, one Swedish national goal for better health for elderly was to decrease drug-drug interactions. We performed an intervention, where the physicians in primary health care were alerted to which of their patients had a drug-drug interaction. The physicians received a letter with patient information and recommendations on how to act. They were requested to review if the interactions still

Quantitative imaging by automated bone scan index (BSI) as a response biomarker in standard clinical care of patients with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide

Background: Enzalutamide (ENZ), an androgen receptor antagonist therapy, was approved for patients (pts) with mCRPC. However, in standard of care for mCRPC pts, change in prostate specific antigen (PSA) is not accepted as an efficacy response measurement and the radiological change is inadequately measured in an interpreter-dependent subjective analysis of bone scan. Therefore, an objective effica

Knowledge and Awareness of Algerian Students about Cervical Cancer, HPV and HPV Vaccines : A Cross-Sectional Study

Cervical cancer is one of the most recurrent and dangerous female cancers in Algeria and worldwide. It is mainly caused by human papillomaviruses (HPV), which can induce other cancers as well. Although it can be fatal, cervical cancer is one of the most preventable and manageable cancers. While HPV vaccination is the key weapon to win the battle against this pathology, it is still not approved in

Monkeypox : A Comprehensive Review

The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkey

Successive Cancellation Decoding of Single Parity-Check Product Codes : Analysis and Improved Decoding

A product code with single parity-check component codes can be described via the tools of a multi-kernel polar code, where the rows of the generator matrix are chosen according to the constraints imposed by the product code construction. Following this observation, successive cancellation decoding of such codes is introduced. In particular, the error probability of single parity-check product code

Distant reading televised public information : The communication of Swedish government agencies, 1978-2020

This study focuses on the Swedish public information programme Anslagstavlan, a unique audiovisual communication tool for Swedish government agencies since 1972 and an important part of Sweden’s audiovisual cultural heritage. Whereas digital research methodologies for data-driven text analysis have been developed and established over the last decades, the use of digital tools in the analysis of au

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite nu

The influence of multiple groups of biological ice nucleating particles on microphysical properties of mixed-phase clouds observed during MC3E

A new empirical parameterization (EP) for multiple groups of primary biological aerosol particles (PBAPs) is implemented in the aerosol-cloud model (AC) to investigate their roles as ice nucleating particles (INPs). The EP describes the heterogeneous ice nucleation by (1) fungal spores, (2) bacteria, (3) pollen, (4) detritus of plants, animals, and viruses, and (5) algae. Each group includes fragm

Critical scenario identification for realistic testing of autonomous driving systems

Autonomous driving has become an important research area for road traffic, whereas testing of autonomous driving systems to ensure a safe and reliable operation remains an open challenge. Substantial real-world testing or massive driving data collection does not scale since the potential test scenarios in real-world traffic are infinite, and covering large shares of them in the test is impractical

Assessing Climate Adaptation and Flood Security Using a Benchmark System : Some Swedish Water Utilities as Good Learning Examples

The 2020 Sustainability Index (SI), a benchmark system, shows that 2% of the 184 municipal water and wastewater utilities (WWS) in Sweden have a good performance level (green), i.e., they meet all benchmark requirements for the “climate adaptation and flood safety” (“CA and FS”). In this study, ten Swedish WWS organizations were selected and studied in depth. The goal was to present them as good l

Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells

Tissue damage, epithelial alterations, and intraepithelial presence of mast cells (MCs) are characteristics of asthma pathogenesis. Increased alveolar infiltration of MC populations has also been identified as a feature of asthma and other chronic respiratory diseases. The asthma associated receptor, urokinase plasminogen activator receptor (uPAR), has been shown to regulate bronchial epithelial r

Adaptive capacity in the multi-level management system of migratory waterbirds: a case study of participatory goose management in Sweden

Adaptive management (AM) is one approach to manage migratory waterbirds, butobstacles to the implementation of AM require adaptive capacities in themanagement system (rules, institutions, action situations). This study aims toexamine the adaptive capacity of participatory goose management in Sweden.Considering the biophysical and institutional context, we analyzed how tangible,individual, and gove

Subjective experience of fear and the cognitive interpretation of large carnivores

This study describes the psychological characteristics of fear of brown bear (Ursus arctos) and wolf (Canis lupus) using the Cognitive Vulnerability Model. Data were obtained from a survey of 154 stakeholders. Subjective experience of fear was primarily linked to the perceived danger or harm that the animal represents and the perceived uncontrollability of the person's own response when encounteri