Sökresultat

Filtyp

Din sökning på "*" gav 534693 sökträffar

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

Background Epithelial damage, repair and remodelling are critical features of chronic airway diseases including chronic obstructive pulmonary disease (COPD). Interleukin (IL)-33 released from damaged airway epithelia causes inflammation via its receptor, serum stimulation-2 (ST2). Oxidation of IL-33 to a non-ST2-binding form (IL-33ox) is thought to limit its activity. We investigated whether IL-33

Contemporary Nordic Histories of the Universities : The Renewal of An Old Field

Historians of the universities have not always belonged to the avantgarde of historical research. On the contrary, many studies of the universities have tended to be rather traditional and narrow-minded. In recent years, however, the surge in the history of knowledge has opened up novel perspectives and given new impulses to how to write the history of the universities. In this presentation, Johan

Numerical schemes for a moving-boundary convection-diffusion-reaction model of sequencing batch reactors

Sequencing batch reactors (SBRs) are devices widely used in wastewater treatment, chemical engineering, and other areas. They allow for the sedimentation and compression of solid particles of biomass simultaneously with biochemical reactions with nutrients dissolved in the liquid. The kinetics of these reactions may be given by one of the established activated sludge models (ASMx). An SBR is opera

Smooth band termination at high spin in 113I

The 113I nucleus has been studied using the 58Ni(58Ni,3p) reaction at 250 MeV with the Gammasphere/ Microball facility. Gamma-ray three-and four-fold data gated by charged particle combinations were analyzed. Multipolarities of the γ rays were assigned following the angular correlation measurements. The present study is focused on the high spin properties, where the structure is dominated by 2p-2h

Targeting neurotrophin and nitric oxide signaling to promote recovery and ameliorate neurogenic bladder dysfunction following spinal cord injury – Mechanistic concepts and clinical implications

This review summarizes the presentations made to a workshop entitled “Targeting Neurotrophin and Nitric Oxide Signaling to Promote Recovery and Ameliorate Neurogenic Bladder Dysfunction following Spinal Cord Injury – Mechanistic Concepts and Clinical Implications” at the International Continence Society (ICS) 2022 Vienna Meeting. Spinal cord injury (SCI; T8-T9 contusion/transection) causes impaire

Clinical use of an emergency manual by resuscitation teams and impact on performance in the emergency department : A prospective mixed-methods study protocol

Introduction Simulation-based studies indicate that crisis checklist use improves management of patients with critical conditions in the emergency department (ED). An interview-based study suggests that use of an emergency manual (EM) - a collection of crisis checklists - improves management of clinical perioperative crises. There is a need for in-depth prospective studies of EM use during clinica

Positioning for lumbar puncture in newborn infants

BACKGROUND: Lumbar puncture is a common invasive procedure performed in newborns for diagnostic and therapeutic purposes. Approximately one in two lumbar punctures fail, resulting in both short- and long-term negative consequences for the clinical management of patients. The most common positions used to perform lumbar puncture are the lateral decubitus and sitting position, and each can impact th

Acupuncture for procedural pain in newborn infants

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of acupuncture in newborn infants undergoing painful procedures.

The Content of Physiotherapy and Factors Impacting on Reablement – A National Study

Purpose: Reablement is a multidisciplinary intervention aimed at promoting function and independence for people with functional decline. Detailed descriptions of various professions’ actions are needed for organization and evaluation of reablement services. This study describes physiotherapy practice in a reablement context in Swedish municipalities, focusing on the content and magnitude of interv

Periodontitis and NAFLD-related diseases : A bidirectional two-sample Mendelian randomization study

Background: Epidemiological studies have shown an association between periodontitis and nonalcoholic fatty liver disease (NAFLD)-related diseases. However, a causal relationship between these two diseases remains unclear. To examine the causal relationship between these two diseases, we conducted a bidirectional two-sample Mendelian randomization (MR) analysis using genetic markers as proxies. Met

Parental Access to Healthcare following Paediatric Surgery—The Precarious Role of Parents as Providers of Care in the Home

Access to healthcare can facilitate parents’ self-management of their children’s care. Healthcare access can be described as consisting of six dimensions: approachability, acceptability, affordability, availability, appropriateness, and aperture. The aim of this study was to analyse these dimensions of healthcare access experienced by parents caring for their children at home following paediatric

Use of information and communication technology in occupational therapy for older adults

Background: Information and communication technology (ICT) provides one solution to meet increasing demands for occupational therapy for older adults. Aims/Objectives: To examine if and how municipality-based occupational therapists (OTs) include ICT in their work, and which factors are associated with use of occupational therapy at a distance. Material and Methods: Survey study including 167 OTs.

“If the Kingdom be Ruled According to the Tao” : Politics as “Eastern Wisdom” in Aleister Crowley’s Reception of the Daodejing

The fascination with the “Eastern Wisdom” exhibited among esoteric movements in the late nineteenth and early twentieth century is often understood as an interest in spirituality. Existing research has focused on how these movements took an interest in beliefs in doctrines like karma and reincarnation, as well as in practices of meditation and divination. Although this characterization is broadly

Protein Biomarker Signatures in Precision Diagnostics of Cancer

Early diagnosing and patient individualized biomarker profiling are two key elements for curative interventions within cancer. Detecting cancer, when the tumor is still localized, allows for a more efficient treatment-either through surgery alone or with systemic therapies, treating a naïve and less heterogeneous tumor cell population. Developing tumors consist of complex and stage-dependent genet

Elevated circulating follistatin associates with increased risk of mortality and cardiometabolic disorders

Background and aims: Previous study showed that elevated circulating hepatokine follistatin (FST) associates with an increased risk of type 2 diabetes by inducing adipose tissue insulin resistance. Here we explore further the relationships between plasma FST levels with mortality and health outcomes. Methods and results: The population-based Malmö Diet Cancer cardiovascular cohort (n = 4733, age 4

Arbetsterapeuters erfarenheter av att stödja elever med problematisk skolfrånvaro i grundskolan

Bakgrund: Problematisk skolfrånvaro har på senare år ökat och kommit att bli ett samhälleligt problem. Barns framtid och utveckling är till stor del präglad av att de klarar av skolan. Ett arbetsterapeutiskt perspektiv som innebär förståelse för hur miljön kan påverka aktivitetsutförandet kan bidra till att förbättra elevers delaktighet i skolan. Syfte: Syftet är att undersöka arbetsterapeuters erBackground: Problematic school absenteeism has increased in recent years and has become a societal problem. Children's future and development is largely determined by their ability to complete school. An occupational therapy perspective that involves an understanding of how the environment can affect the performance of activities can contribute to improving students' participation in schoo