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A Molecular Dissection of Mantle Cell Lymphoma - From gene expression analysis to functional evaluation of selected targets
Popular Abstract in Swedish Årligen diagnostiseras cirka 60 000 nya fall av cancer i Sverige (Socialstyrelsen, 2015), och var tredje person beräknas få en cancerdiagnos under sin livstid. Trots stora framsteg inom forskning och utveckling är cancer, näst efter hjärt- och kärlsjukdomar, den vanligaste dödsorsaken i vårt samhälle. Bland de tio vanligaste formerna av cancer hör lymfom, vilket är etMantle cell lymphoma (MCL) is an aggressive form of B-cell lymphoma (BCL) with poor clinical outcome. In this thesis, which is based upon five original papers, different approaches have been used to pinpoint and investigate molecular events that promote MCL tumor growth, progression or resistance to treatment. The aim has been to identify novel targets with the potential to eradicate malignant cel
Properties of Discontinuous Bifurcations Solutions in Elasto-Plasticity
Explicit expressions for the spectral properties of the bifurcation problem involving discontinuities for general elastic-plastic materials are presented. It then follows that the classical value of the critical hardening modulus derived by Rice (1976. Proc. 14th IUTAM Congr., Delft, The Netherlands, pp. 207–220, North Holland, Amsterdam.) is, in fact, the only possible one. Furthermore, from the
Balanspartier i regeringsbildningar
John Cowper Powys: A Master of Nuances and Variations
Addressing smoking during pregnancy:The challenge to start from the woman's view
Popular Abstract in Swedish Kvinnor känner till att det är riskabelt att röka när de blir gravida. Trots detta så slutar bara omkring hälften i Sverige och var tredje kvinna i många andra länder att röka när de blir gravida. Syftet i den här avhandlingen har varit att studera varför det är så svårt för gravida kvinnor att sluta röka. Problemområdet har studerats med olika utgångspunkter; gravida kThe aim of this thesis has been to increase understanding on the process of smoking cessation during pregnancy from the perspective of learning. The smoking pattern before and after pregnancy related to health, Sense of Coherence (SOC) and social issues was studied among all pregnant women in south-east Skåne during the period March 1994 to August 1995. They were asked to fill in a questionnaire d
Captured Countryside? Stability and Change in Sub-national Support for African Incumbent Parties
Many existing accounts of African elections assume that voters base their electoral decisions on cues and incentives that are anchored in highly stable ethnic cleavage structures. Yet several newer contributions to the study of African electoral politics have questioned the ethno-clientelistic voting thesis and highlighted other determinants of vote choice, such as class, ideology and performance
Lag som offentlig uppfostran : om Thomas av Aquinos rättsfilosofi
Issues in Manipulator Programming
Regeneration of peripheral nerves: The role of protein phosphorylation
The involvement of phosphorylation/dephosphorylation reactions in peripheral nerve regeneration was studied in frog and adult mouse during in vivo and in vitro conditions. By comparing phosphoprotein patterns in normal and regenerating frog sciatic nerves a regeneration related phosphoprotein (PP90) was found. The kinase acting on PP90 was pharmacologically distinguished from PKC and PKA but sensi
Nordic Regional Innovation Systems: An Analysis of the Region of East Gothia, Sweden
Svensk rätts internationella beroende
Choir in Focus 2010
Choir singing, choral practice and singing in general are explored as research objects in a variety of disciplines. Together, they describe a complex and multifaceted field of interesting cultural-historical, pedagogical, sociological, and psychological and music related topics. The disciplines that work with choir related research differ in theoretical and methodological traditions and vary with
On the analysis of prosody in interaction
Tystnadsplikt eller informationsrätt? - Om intressekonflikter vid revision av internationella koncerner
Metodik för karakterisering i vindtunnel av aerosolprovtagning med personburen utrustning
Do Swedish civil status record qualify to be recognized in the other EU member states?
ORF-MOSAIC for Adaptive Control of a Biomimetic Arm
This study is an attempt to take advantage of a cerebellar model to control a biomimetic arm. The cerebellar controller is a modified MOSAIC model which adaptively controls the arm. We call this model ORF-MOSAIC (Organized by Receptive Fields MOdular Selection And Identification for Control). The arm features a musculoskeletal model which is controlled through muscle activations by means of optimi
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