Sialic acids derivatised at C-4 as ligands for bacterial SSS transport proteins
This master thesis project focuses on establishing a synthetic method with the prospect of developing new antibacterial agents. Due to the increment of resistant strains of bacteria throughout the world, this area of research is well motivated. The nine-carbon sugar - sialic acid - is a highly prevalent communication molecule on human cell surfaces. It signals that the cells are endogenous and not