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uKNIT: Breaking Round-alignment for Cipher Design : Featuring uKNIT-BC, an Ultra Low-Latency Block Cipher

Automated cryptanalysis has seen a lot of attraction and success in the past decade, leading to new distinguishers or key-recovery attacks against various ciphers. We argue that the improved efficiency and usability of these new tools have been undervalued, especially for design processes. In this article, we break for the first time the classical iterative design paradigm for symmetric-key primit

Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation

As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (

The prognostic significance of stress-phenotyping for stroke incidence : the Malmö Diet and Cancer Study

BACKGROUND: Self-reported mental stress is not consistently recognized as a risk factor for stroke. This prompted development of a novel algorithm for stress-phenotype indices to quantify chronic stress prevalence in relation to a modified stroke risk score in a South African cohort. The algorithm is based on biomarkers adrenocorticotrophic hormone, high-density lipoprotein cholesterol, high-sensi

Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease?

Background and Aims: Crohn's disease (CD) is associated with a disturbed intestinal barrier. Permeability studies have focused on inert molecules, but little is known about transepithelial transport of macromolecules with antigenic potential in humans. The aim of this study was to quantify permeation and to characterize passage routes for macromolecules in ileal mucosa in CD. Methods: Noninflamed

Permeability of intestinal mucosa from urinary reservoirs in man and rat

Objective: To evaluate the barrier properties of intestinal mucosa chronically exposed to urine and to evaluate possible differences between ileal and colonic segments used in the reconstruction of the urinary tract. Materials and methods: Mucosal specimens from patients with continent reservoirs with an abdominal stoma, or orthotopic neobladders constructed from colonic segments, were obtained at

Developmental regulation of the porcine exocrine pancreas by glucocorticoids

The possible role of CORTISOL in development of the exocrine pancreas was investigated. In the first study, fetal pigs were removed from the uterus by caesarean section (pentobarbitone anesthesia) and the pancreas collected from 51 69 to 109-day-old fetuses (term = 114 ± 2 days). Of these, 15 88 to 90-day-old fetuses had been infused subcutaneously for 6 days with either saline, adrenocorticotropi

NFTs for Artists: Hype or a Whole New Business Paradigm?

The post-pandemic rise of non-fungible tokens (NFTs) within the music industry has presented a disruptive innovation that has the potential to reshape traditional business models, offering artists new revenue streams and direct-to-fan engagement opportunities. As music NFTs grow in prominence, they challenge the entrenched systems of royalties and intermediaries, prompting questions about their lo

The association between novel urinary kidney damage biomarkers and coronary atherosclerosis in an apparently healthy population

Several novel urinary kidney damage biomarkers predict the progression of kidney disease. However, the relations of these biomarkers to atherosclerosis, a major consequence of kidney disease, are less studied. Urinary levels of several biomarkers, including kidney injury molecule-1 (KIM-1), osteopontin, epidermal growth factor, and Dickkopf-3, were assessed in participants enrolled in the Swedish

A Cognitive Model of Visuospatial Complexity for Interactive Immersive Media Design

The development of immersive visuoauditory media brings to the fore several design challenges concerning cognitive human factors, such as visual perception, embodied interaction, and emotional engagement. With a focus on visual perception, our research emphasises a systematic study of embodied multimodal interaction in immersive settings and provides a cognitive model of visuospatial complexity th

Coup d´état in KGB style? : A new look at the conflict within the Soviet Communist leadership during the early Brezhnev era

The article analyzes power structures and relations in the Soviet Union in the mid-1960s, i.e., in the first years of Leonid Brezhnev's rule. It shows how Brezhnev limited the control mechanisms of power introduced by Nikita Khrushchev in order to consolidate his own position. The analysis contributes to a better understanding of the failure of Khrushchev's "reform communism" and the construction

3D Printing of Polyurethanes for Biomedical Applications

The use of three-dimensional printing (3DP) for rapid prototyping and manufacturing has brought new insights for component production following customized and complex geometrical designs. Due to its excellent mechanical strength, flexibility and potential biocompatibility, polyurethane (PU) has been developed for fabricating convoluted biomedical devices by 3DP. Such a manufacturing technic offers

Elevations in plasma glucagon are associated with reduced insulin clearance after ingestion of a mixed-macronutrient meal in people with and without type 2 diabetes

Aims/hypothesis: The temporal suppression of insulin clearance after glucose ingestion is a key determinant of glucose tolerance for people without type 2 diabetes. Whether similar adaptations are observed after the ingestion of a mixed-macronutrient meal is unclear. Methods: In a secondary analysis of data derived from two randomised, controlled trials, we studied the temporal responses of insuli

Clinical guidelines for the management of mammographic density : a systematic review of breast screening guidelines worldwide

Background: High breast density is an independent risk factor for breast cancer and decreases the sensitivity of mammography. This systematic review synthesizes the international clinical guidelines and the evidence base for screening and supplemental screening recommendations in women with dense breasts. Methods: A systematic search of CINHAL, Embase, and Medline databases was performed in August