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Locative and Directional Prepositions in Conceptual Spaces : The Role of Polar Convexity

We approach the semantics of prepositions from the perspective of conceptual spaces. Focusing on purely spatial locative and directional prepositions, we analyze both types of prepositions in terms of polar coordinates instead of Cartesian coordinates. This makes it possible to demonstrate that the property of convexity holds quite generally in the domain of prepositions of location and direction,

Combinations of single-top-quark production cross-section measurements and

This paper presents the combinations of single-top-quark production cross-section measurements by the ATLAS and CMS Collaborations, using data from LHC proton-proton collisions at s = 7 and 8 TeV corresponding to integrated luminosities of 1.17 to 5.1 fb−1 at s = 7 TeV and 12.2 to 20.3 fb−1 at s = 8 TeV. These combinations are performed per centre-of-mass energy and for each production mode: t-cha

Kain, Abel, boys will be boys

Det är inte fråga om hur det kommer sluta. Vi vet redan hur det kommer sluta, vi känner till det slutet, "det våldsamma slutet, då hjärnan rinner ut efter upprepat våld mot skallbenet och likstelheten inträder". Det handlar inte om hur det slutar, har slutat, kommer sluta. Det är redan känt, det är redan skrivet, att "när de voro ute på marken överföll Kain sin broder Abel och dödade honom".

Monitoring finer-scale population density in urban functional zones : A remote sensing data fusion approach

Spatial distribution information on population density is essential for understanding urban dynamics. In recent decades, remote sensing techniques have often been applied to assess population density, particularly night-time light data (NTL). However, such attempts have resulted in mapped population density at coarse/medium resolution, which often limits the applicability of such data for fine-sca

Critical analysis of constitutive functions for hindered settling velocity in 1-D settler models

Advanced 1-D models for secondary clarifiers aim to incorporate more realism by explicitly accounting for several phenomena that influence the settling process. For each of them a valid mathematical expression needs to be selected to obtain a calibrated model that can be used for operation and control. The presented work evaluates different available expressions for hinderedsettling based on long

Analyses of activated sludge processes consisting of a plug-flow reactor and a non-ideal settler

An activated sludge process (ASP) consisting of a plug-flow reactor (PFR) and a non-ideal settler is modelled and analysed. One soluble substrate component and one particulate biomass are assumed. The biomass growth rate is described by a Monod function. The settler model includes hindered settling and compression. A model describing the steady-state behaviour of the ASP is derived which constrain

Is Vtb ≃ 1?

The strongest constraint on Vtb presently comes from the 3 × 3 unitarity of the CKM matrix, which fixes Vtb to be very close to one. If unitarity is relaxed, current information from top production at Tevatron still leaves open the possibility that Vtb is sizably smaller than one. In minimal extensions of the standard model with extra heavy quarks, the unitarity constraints are much weaker, and th

Top pair invariant mass distribution : A window on new physics

We explore in detail the physics potential of a measurement of the t invariant mass distribution. First, we assess the accuracy of the best available predictions for this observable and find that in the low invariant mass region, the shape is very well predicted and could be used to perform a top mass measurement. Second, we study the effects of a heavy s-channel resonance on the t invariant mass

Receptor-mediated internalization of bradykinin : DDT1 MF-2 smooth muscle cells process internalized bradykinin via multiple degradative pathways

This study was undertaken to evaluate the role of internalization in the action of the peptide autacoid bradykinin (BK). At 4°C [3H]BK binds to an apparently single class of B2 kinin receptors on DDT1 MF-2 smooth muscle cells (C. M. Munoz, S. Cotecchia, and L. M. F. Leeb-Lundberg, manuscript submitted). At this temperature the [3H]BK binding was confined exclusively to the cell surface. On the oth

Barbiturates allosterically inhibit GABA antagonist and benzodiazepine inverse agonist binding

Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [3H]bicuculline methochloride (BMC) to γ-aminobutyric acid (GABA) receptor sites and the binding of [3H]β-carboline-3-carboxylic acid methyl ester (βCCM) to benzodiazepine receptor sites in mammalian brain. These concentration-dependent effects were chemically specific and stereospecific in a mann

Interaction of barbiturates of various pharmacological categories with benzodiazepine receptors

Numerous barbiturates, such as (±)-pentobarbital, reversibly enhance the affinity for equilibrium binding of [3H]diazepam to well-washed rat cortical membranes in a chloride-dependent and picrotoxinin-sensitive manner [Leeb-Lundberg et al., Proc. Natl. Acad. Sci. U.S.A. 77:7468-7472 (1980)]. The chemical specificity and stereospecificity of this barbiturate effect in vitro has been examined in det

Perturbation of benzodiazepine receptor binding by pyrazolopyridines involves picrotoxinin/barbiturate receptor sites

The two pyrazolopyridines, etazolate (SQ20009) and cartazolate (SQ65396), enhance the binding of [3H]diazepam to benzodiazepine receptor sites in rat brain. This enhancement is due to a change in affinity without a change in maximal binding. Pentobarbital also enhances [3H]diazepam binding by lowering the K(D). Pentobarbital gives a maximal enhancement of benzodiazepine binding slightly greater th