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The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy. Another goal is achieving a stable deep molecular response (DMR) and discontinuing medication for treatment-free remission (TFR). The European LeukemiaNet convened an expert panel to critically evaluate and update the evi
The global financial crisis has highlighted the importance of financial factors on economic performance. Most of the existing research analyses the contemporary experience, and especially the 1980 s onwards. This paper investigates the effects of stock prices, real estate prices and debt on consumption and investment expenditures by estimating consumption and investment equations for about 110 yea
BACKGROUND/AIM: Cervical cancer is the most common cancer among women in Ethiopia. The objective was to evaluate the participation rate of a free of charge vaginal self-sample (Aptima multitest swab, Hologic) for the detection of human papillomavirus (HPV) in an Ethiopian cohort. PATIENTS AND METHODS: Specimens were collected from women employed by Ethiopian Airlines in Addis Abeba (N=5950). Sampl
In this opinion in the Dutch financial newspaper I discuss the economic rationale behind the phenomena that charities donate to companies. This is a new way in which charities try to achieve the greatest possible impact and, for example, ensure that vaccines are also developed for commercially uninteresting markets. The Dutch tax authorities are sometimes reluctant to view this as public benefit e
The relative contribution of different microbial groups to soil organic matter (SOM) turnover and utilisation of rhizodeposits during a cropping season has remained largely unknown. We used a long-term field experiment (started in 1956), in which C3 crops were replaced with C4 silage maize in 2000, to investigate dynamics of fungi and bacterial groups and their utilisation of ‘young-C4’ and ‘old-C
Background: Pediatric asthma remains a public health challenge with enormous impact worldwide. Objective: The aim of this study was to identify and prioritize unmet clinical needs in pediatric asthma, which could be used to guide future research and policy activities. Methods: We first identified unmet needs through an open-question survey administered to international experts in pediatric asthma
Redaktionell introduktion till tidskriften Fronesis nr 64-65, tema Algoritmer.
This article introduces a logic to reason about a well-known model of opinion dynamics in social networks initially developed by Morris DeGroot as well as Keith Lehrer and Carl Wagner. The proposed logic is an extension of Łukasiewicz' fuzzy logic with additional equational expressivity, modal operators, machinery from hybrid logic and dynamic modalities. The model of opinion dynamics in social ne
Människor kategoriserar och ordnar världen omkring sig genom att konstruera gränser, producera värderingar, rangordningar och kvantifierade data. Att undersöka hur sådana ordningar konstrueras, reproduceras och ifrågasätts har länge varit en central fråga för kunskapssociologin. Att förstå sådana processer idag innebär att vi i allt större utsträckning måste förstå hur algoritmer kommit att bli en
The growth of Bi on both the In-terminated (A) face and the As-terminated (B) face of InAs(1 1 1) has been investigated by low-energy electron diffraction, scanning tunnelling microscopy, and photoelectron spectroscopy using synchrotron radiation. The changes upon Bi deposition of the In 4d and Bi 5d5/2 photoelectron signals allow to get a comprehensive picture of the Bi/InAs(1 1 1) interface. Fro
The role of values in climate-related decision-making is a prominent theme of climate communication research. The present study examines whether forest professionals are more driven by values than scientists are, and if this results in value polarization. A questionnaire was designed to elicit and assess the values assigned to expected effects of climate change by forest professionals and scientisThe role of values in climate-related decision-making is a prominent theme of climatecommunication research. The present study examines whether forest professionals are more drivenby values than scientists are, and if this results in value polarization. A questionnaire was designedto elicit and assess the values assigned to expected effects of climate change by forest professionalsand scientists w
Why did heraldry originate? This question has often been answered with references to changes in the military equipment in the 12th century, especially the introduction of the closed helmet. But recent research gives reason to question this theory. The introduction of the closed helmet and the origin of heraldry did not coincide chronologically. There are other changes in the military equipment, anWhy did heraldry originate? This question has often been answered with references to changes in the military equipment in the 12th century, especially the introduction of the closed helmet. But recent research gives reason to question this theory. The introduction of the closed helmet and the origin of heraldry did not coincide chronologically. There are other changes in the military equipment, an
A channel sounder is an advanced measurement system to estimate the behavior of wireless propagation channels. In this paper, we present the antenna array design for a 28GHz massive multiple-input multiple-output system, capable of measuring 256×128 dual-polarized channels, including dynamic properties of angular, delay, Doppler, and polarization parameters, respectively. Unique in comparison to o
In this work, X-ray absorption spectroscopy (XAS) and site-selective X-ray emission spectroscopy (XES) were used to measure the oxygen K-edge (OC=O,1s and OCO − ,1s) of oxalic acid, with theoretical calculations performed to reproduce the spectra observed. Structure sampling of a cluster model was performed using an ab initio molecular dynamics trajectory. Relative XES intensities from core-hole e
Multinuclear metal active sites are widely used as catalytic reaction centers in metalloenzymes and generally show high catalytic activity. For example, laccases are known to catalyze the oxygen reduction reaction (ORR) to water at a multinuclear copper site with almost no energy loss. The ORR is an important reaction not only in oxygenic respiration but also in future energy generation devices su
Purpose: The aim of this study was to compare the effects of four months of two types of structured training regimes, static standing (StS) versus dynamic standing (DyS), on passive range of motion (PROM) and spasticity in the hip among non-ambulatory children with cerebral palsy.Method: Twenty non-ambulatory children with cerebral palsy participated in an exercise intervention study with a crosso
Biographical essay on Märta Strömberg, professor of Archaeology in Lund. She was one of the first female archaeologists that took place in the university world. She became a committed mentor for generations of students, doctoral students and colleagues. Her archaeological investigations of the Stone Age megalithic tombs, the Bronze Age and the Iron Age grave fields and settlements became methodolo
