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The polyamines putrescine, spermidine, and spermine are organic cations that are required for cell growth and differentiation. Ornithine decarboxylase (ODC), the first and rate-limiting enzyme in the polyamine biosynthetic pathway, catalyzes the conversion of ornithine to putrescine. As the polyamine biosynthetic pathway is essential for the growth and survival of Leishmania donovani, the causativ

The first essay examines the outcome in a competitive private pension market characterised by adverse selection. In addition to using the private pension market, the consumers can save in a bequeathable asset. Assuming two types of agents and using the Coalition Proof Equilibrium with Private Information we show that the outcome in the private pension market may be separating or pooling. A separat

A Rhesus monkey, serologically grouped as B, has been shown to excrete low-molecular-weight carbohydrate material in urine closely related to that found in human urine. Galactose feeding resulted in the excretion of a trisaccharide which was shown to be identical to the trisaccharide isolated from the urine of group B humans under the same conditions. Experiments in which [14C]galactose was admini

Neuronal connections and cortical maps are continuously remodeled by our experience. Knowledge of the potential capabilityof the brain to compensate for lesions is a prerequisite for optimal stroke rehabilitation strategies. Experimental focal cortical lesions induce changes in adjacent cortex and in the contralateral hemisphere. Neuroimaging studies in stroke patients indicate altered poststroke

This thesis concerns both design and optimization of NMR imaging systems and studies on non-thermal biological effects of electromagnetic fields. These two research fields are linked together by the fact that humans are subject to static and pulsed magnetic fields as well as to magnetic radio frequency fields (RF) during an NMR imaging investigation. This work bridges the gap between technology, p

Motivated by a desire to understand and optimize combustion in spark-ignition (SI) engines, laser techniques have been developed for measurement of fuel and residual gas, respectively, in the precombustion mixture of an operating SI engine. The primary objective was to obtain two-dimensional, quantitative data in the vicinity of the spark gap at the time of ignition. A laser-induced fluorescence

Many different factors such as process dynamics, disturbances, process uncertainties and actuator saturation have to be considered when designing a control system. It is important to be aware of factors that limits the achievable performance. In this paper we attempt to formulate some problems that capture the essence of the design problem in a simple way. Results of this type are a complement to

To evaluate the dose values predicted by several calculation algorithms in two treatment planning systems, Monte Carlo (MC) simulations and measurements by means of various detectors were performed in heterogeneous layer phantoms with water- and bone-equivalent materials. Percentage depth doses (PDDs) were measured with thermoluminescent dosimeters (TLDs), metal-oxide semiconductor field-effect tr

The European Respiratory Society's study on chronic obstructive pulmonary disease (EUROSCOP) is a multicentre study performed initially in 12 countries to assess the effect of 3 years' treatment with inhaled corticosteroids on lung function decline in smokers with chronic obstructive pulmonary disease (COPD). It aimed at recruiting 50 subjects in 50 European centres. This study discusses the most

Purpose – The purpose is to describe the advantages, challenges and uncertainties of collecting and analyzing data using participant observation in logistics research. Design/methodology/approach – Experiences from a participant observation study of an interorganizational RFID implementation in an international environment are presented and reflected on. The RFID implementation included complex in

Using a many-particles plus rotor model, wobbling excitations built on top of a triaxial superdeformed band in Lu-163 are investigated. By extracting all parameters for the rotor from a mean field calculation a good correspondence with calculations based on the random-phase approximation is achieved.