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Mammalian polyamine carriers have not yet been molecularly identified. The fluoroprobe Spd-C2-BODIPY faithfully reports polyamine transport and accumulates almost exclusively in polyamine-sequestering vesicles (PSVs). Polyamines might thus be imported first by a plasma membrane carrier and then sequestered into pre-existing PSVs (model A), or be directly captured by polyamine receptors undergoing

In this study the elasto-plastic constitutive equations are reformulated using the assumption of constant strain rate direction within a load increment. This assumption allows the constitutive evolution laws to be rewritten as ordinary differential equations (ODEs). The set of ODEs is reduced using the Krieg and Krieg description of the deviatoric stress space. Although this approach does generall

We demonstrate a method for growth of GaP nanocrystals on Si(001), developed to avoid defects related to antiphase domain boundaries in the proximity of the GaP/Si interface. The technique is based on sub-mum-sized selective-area epitaxy of GaP on atomically flat Si in masked openings. We have used field-emission scanning electron microscopy together with transmission electron microscopy to illust

The aim of this study is to analyse the spatial variability of meso-scale precipitation in Scania and to assess the influence of synoptic scale atmospheric circulation. The modes of spatial variation are revealed by EOF analysis of monthly precipitation totals between 1963 and 1990, which were obtained from a dense rain-gauge network in Scania. southern Sweden. The influence of local physiography

The electroenzymatic reactions of Trametes hirsuta laccase in the pure organic solvent dimethyl sulfoxide (DMSO) have been investigated within the framework for potential use as a catalytic reaction scheme for oxygen reduction. The bioelectrochemical characteristics of laccase were investigated in two different ways: (i) by studying the electroreduction of oxygen in anhydrous DMSO via a direct ele

Object Shift in Swedish is restricted to unstressed pronouns. Sentences where an object pronoun precedes a sentence adverb, such as Han åt den inte ‘(lit.) He ate it not’, are thus well-formed, whereas sentences with a full noun phrase (NP) object preceding a sentence adverb, such as Han åt sylt/sylten inte ‘(lit.) He ate jam/the jam not’, are ill-formed. The neural correlates to violation of this

Beech bark lesions, (Cryptococcus fagisuga), the most common lichen and fungi epiphytes on beech (Fagus sylvatica) stems were studied at 48 sites in Scania, south Sweden. Different site variables and the influence of nitrogen deposition were investigated. The field vegetation and lichens were used as biological indicators by calculating indices for nutrition status, toxicity, pH, light and moistur

Cyclin E is one of the key regulators of the G(1)/S transition in the cell cycle. Overexpression of cyclin E has been observed in several malignancies and is associated with high proliferation, aberrant expression of other cell cycle regulators and chromosomal instability in vitro. To explore potential associations between cyclin E deregulation and inactivation of the p53 tumor suppressor gene in

Review of “Natalie Wood: a life” by Gavin Lambert (2004)

The internal carotid artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats has a thicker media than that of normotensive Wistar Kyoto rats as early as 15 days of age; furthermore, the media-to-lumen ratio is increased in the larger pial arteries. Since several studies have indicated that the mean arterial pressure is slightly elevated in spontaneously hypertens

Isolation and expansion of neural stem cells (NSCs) of human origin are crucial for successful development of cell therapy approaches in neurodegenerative diseases. Different epigenetic and genetic immortalization strategies have been established for long-term maintenance and expansion of these cells in vitro. Here we report the generation of a new, clonal NSC (hc-NSC) line, derived from human fet

Background. Nurse managers act under constant pressure to develop strategies in response to professional challenges within a changing and restructured health care system. When such environmental stress is present, they need access to sufficient psychosocial recourses. Aim. The study aimed to investigate whether nurse managers' professional networks, psychosocial work conditions, job support, soci

The Ag II spectrum emitted from hollow cathode discharges has been recorded in the region 940–8500 Šwith Fourier transform and high dispersion photographic instruments. 311 lines have been classified and measured at high accuracy (±0.03–0.003 cm-1 above 2000 Ŭ ±0.002–0.0005 Šin the VUV region). Improved energy level values have been derived from the lines, and 24 new odd levels have been found. Th

It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fracture incidence and mortality to adjust intervention thresholds. Ten-year probabilit

The long-term fates of duplicate genes are well studied both empirically and theoretically, but how the short-term evolution of duplicate genes contributes to phenotypic variation is less well known. Here, we have studied the genetic basis of flowering tithe variation in the disomic tetraploid Capsella bursa-pastoris. We sequenced four duplicate candidate genes for flowering time and 10 background

Estimating the extinction risk of natural populations is not only an urgent problem in conservation biology but also involves some profound aspects of population dynamics. Apart from the obvious case of a continuous decrease in a population's carrying capacity, understanding the extinction process necessarily includes environmental and demographic stochasticity. Here, we build from first principle