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Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: Six-month study

Several studies have shown that alpha-ketoglutaric acid (AKG) increases serum levels of proline and has beneficial effects on skeletal development. We studied the effect of alpha-ketoglutaric (AKG) acid calcium salt (6 g AKG and 1,68 Ca/day) or calcium alone (1.68 Ca/day) on serum C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin (OC), as well as lumbar spine bone minera

An intuitive semiclassical picture of proton structure at small x

A semiclassical description of structure functions in DIS at small x is presented. It gives an intuitive picture of the transition from the Double Leading Log approximation at large Q(2), to the powerlike dependence on x in the BFKL region at limited Q(2). Formal derivations from perturbative QCD, e.g. in the BFKL or the CCFM formalisms, are technically complicated, and therefore such an intuitive

Regional Nutrient Budgets in Forest Soils in a Policy Perspective

Popular Abstract in Swedish Skogen är en av Sveriges mest betydelsefulla naturresurser. Utöver det ekonomiska värdet är skogen även viktig ur ett ekologiskt, socialt och kulturellt perspektiv. För att uppnå ett långsiktigt uthålligt skogsbruk måste alla dessa aspekter beaktas. Uthålliga näringsbalanser i den brukade skogsmarken är nödvändiga för att bevara produktionsförmågan samt minska risken föSweden's forests are one of its most important natural resources, as well as being important from ecological and social perspectives. Nutrient sustainability is essential to maintain the production capacity and reduce the effects of acidification and eutrophication. Nutrient sustainability is strongly affected by anthropogenic influences such as air pollution and forestry practices. Regional asses

Expression of nitric oxide synthase in bladder smooth muscle cells: Regulation by cytokines and L-arginine

Purpose: The expression and regulation of the different isoforms of nitric oxide synthase (NOS) in bladder smooth muscle cells are controversial and to our knowledge have not yet been studied systematically. Therefore, the expression and regulation of NOS were studied in rat bladder smooth muscle cells after stimulation with cytokines, lipopolysaccharide and L-arginine. Materials and Methods: Prim

The COST 259 directional channel model - Part I: Overview and methodology

This paper describes a model for mobile radio channels that includes consideration of directions of arrival and is thus suitable for simulations of the performance of wireless systems that use smart antennas. The model is specified for 13 different types of environments, covering macro- micro- and picocells. In this paper, a hierarchy of modeling concepts is described, as well as implementation as

Elementary excitations of ferromagnetic metal nanoparticles

We present a theory of the elementary spin excitations in transition-metal ferromagnet nanoparticles which achieves a unified and consistent quantum description of both collective and quasiparticle physics. The theory starts by recognizing the essential role played by spin-orbit interactions in determining the energies of ferromagnetic resonances in the collective excitation spectrum and the stren

Albumin adducts in plasma from workers exposed to toluene diisocyanate

Desalted plasma from a 2,4- and 2,6-toluene diisocyanate (2,4- and 2,6-TDI) exposed worker at a factory producing flexible polyurethane foam was separated and fractionated into 200 fractions using ion-exchange chromatography followed by a gel-filtration separation and fractionation into 59 fractions. The corresponding amines (to the isocyanates), 2,4- and 2,6-toluenediamine (2,4- and 2,6-TDA), wer

Deriving and evaluating eye-tracking controlled volumes of interest for variable-resolution video compression

Gaze coordinates are recorded from naive subjects watching a number of video clips. These are used to derive volumes of interest (VOIs) representing the mutual visual interest of the tested subjects. Video frames are then processed in variable resolution contingent on the VOI shapes to produce off-line foveated video. We report on bit rate savings between 30 and 54% due to off-line foveation proir

Evaluation of accuracy in activity calculations for the conjugate view method from monte carlo simulated scintillation camera images using experimental data in an anthropomorphic phantom.

Activity determination from scintillation camera images using the conjugate view method may be inaccurate because of variation in scattered radiation from adjacent organs and activity from overlapping tissues. The aim of this study was to simulate patient scintillation camera images and from these evaluate the accuracy of 2 correction methods. The contribution from overlapping tissue activity was

Physical activity of subjects aged 50-64 years involved in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Objective: To describe physical activity of participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis was restricted to participants in the age group 50-64 years, which was represented in all EPIC centres. It involved 236 386 participants from 25 centre

Reduced expression of BMP-3 due to mechanical loading: a link between mechanical stimuli and tissue differentiation

Mechanical signaling and BMP expression appear to be involved in controlling the differentiation of cartilage in fracture repair, but the connection between mechanics and BMP signaling is not known. In this study of rats, we used a bone chamber to see how BMP gene expression was changed by a mechanical loading regime that induces cartilage formation in this model. We compared the still undifferent

Socioeconomic disadvantage and primary non-adherence with medication in Sweden

Objective. Lack of adherence with pharmacological therapy is a public health concern that compels tremendous costs for the health care system and the community. To analyse the association between socioeconomic disadvantage and primary nonadherence with medication, and to explore possible mediating effects of trust in health care and lifestyle profile. Design. Cross-sectional population-based study

The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells

The clinically relevant polyamine analogue N-1,N-11-diethylnorspermine (DENSPM) inhibits cell growth by down-regulating polyamine biosynthesis, up-regulating polyamine catabolism at the level of spermidine/spermine N-1-acetyltransferase (SSAT), and depleting intracellular polyamine pools. Among human melanoma cell lines, the analogue causes rapid apoptosis in SK-MEL-28 cells and a sharp G(1) arres

The eyes of Macrosoma sp. (Lepidoptera: Hedyloidea): a nocturnal butterfly with superposition optics.

The visual system of nocturnal Hedyloidea butterflies was investigated for the first time, using light and electron microscopy. This study was undertaken to determine whether hedylids possess the classic superposition eye design characteristic of most moths, or apposition eyes of true butterflies (Papilionoidea), and, to gain insights into the sensory ecology of the Hedyloidea. We show that Macros