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Retraction note : CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling (Nature Cell Biology, (2021), 23, 7, (758-770), 10.1038/s41556-021-00702-0)

Retraction to: Nature Cell Biology23:758-770 https://doi.org/10.1038/s41556-021-00702-0 (2021) The authors have retracted this article because it has come to their attention that numerous errors have been identified in the immunoblotting (western blotting) experiments shown in the main Figures 1c, 3a, 4f, 5b and 6b, and the supplementary Figures 1b, 1c, 2d, 3a, 3c, 7f, 8b and 9b. The authors have

Environmental Risk Factors for Parkinson's Disease : A Critical Review and Policy Implications

The age-standardized prevalence of Parkinson's disease (PD) has increased substantially over the years and is expected to increase further. This emphasizes the need to identify modifiable risk factors of PD, which could form a logical entry point for the prevention of PD. The World Health Organization (WHO) has recommended reducing exposure to specific environmental factors that have been reported

Optimizing Remote Sensing Data and Light Use Efficiency Model for Accurate Gross Primary Production Estimation in African Rangelands

This paper focuses on the meticulous selection of optimal remote sensing and climate datasets for Gross Primary Productivity (GPP) estimation in African rangelands. Utilizing Eddy Covariance Flux Tower data, we refine data selection and employ a Light Use Efficiency (LUE) model, with Sentinel 2 for photosynthetically active vegetation quantification, MODIS for Photosynthetically Active Radiation (

Remotely Sensed Herbaceous Rangelands Biomass from African Rangelands : Validation and Uncertainties

This research explores herbaceous biomass estimation in African rangelands through remote sensing, emphasizing challenges and uncertainties. Comparing remote sensing data with ground validation, the study addresses spatiotemporal variations, employing advanced models and validation techniques. Harmonizing and calibrating ground data from four African countries, the research provides insights into

The Post-Stroke Checklist : longitudinal use in routine clinical practice during first year after stroke

Background: Few studies describe the use of the Post-Stroke Checklist (PSC) as a tool for longitudinal stroke follow-up in clinical practice. We mapped the prevalence of stroke-related health problems and targeted interventions at 3 and 12 months post-stroke by using the PSC. Methods: Patients with acute stroke discharged home in 2018–2019 at Skåne University Hospital, Sweden, were invited to part

A sentinel-2 dataset for Uganda

Earth observation data provide useful information for the monitoring and management of vegetation- and land-related resources. The Framework for Operational Radiometric Correction for Environmental monitoring (FORCE) was used to download, process and composite Sentinel-2 data from 2018–2020 for Uganda. Over 16,500 Sentinel-2 data granules were downloaded and processed from top of the atmosphere re

Quantitative detection of macular microvascular abnormalities identified by optical coherence tomography angiography in different hematological diseases

It is now understood that hematological diseases can have detrimental effects on the retina, reducing retinal capillaries, compromising visual function, and potentially causing irreversible visual impairment. Over the years, there has been limited research on macular microvascular abnormalities, such as changes in vessel density and the foveal avascular zone (FAZ) and variations in the severity of

Attention-Aided Outdoor Localization in Commercial 5G NR Systems

The integration of high-precision cellular localization and machine learning (ML) is considered a cornerstone technique in future cellular navigation systems, offering unparalleled accuracy and functionality. This study focuses on localization based on uplink channel measurements in a fifth-generation (5G) new radio (NR) system. An attention-aided ML-based single-snapshot localization pipeline is The integration of high-precision cellular localization and machine learning (ML) is considered a cornerstone technique in future cellular navigation systems, offering unparalleled accuracy and functionality. This study focuses on localization based on uplink channel measurements in a fifth-generation (5G) new radio (NR) system. An attention-aided ML-based single-snapshot localization pipeline is

An international, expert-based, Delphi consensus document on controversial issues in the management of abdominal aortic aneurysms

Objective: As a result of conflicting, inadequate or controversial data in the literature, several issues concerning the management of patients with abdominal aortic aneurysms (AAAs) remain unanswered. The aim of this international, expert-based Delphi consensus document was to provide some guidance for clinicians on these controversial topics. Methods: A three-round Delphi consensus document was

Improvement of energy resolution of ΔE-E CsI/SSD- telescope at measurement of (γ,p)-Reactions using strip information of SSD

Information on the triggered strips of silicon strip detectors of a MAX-lab ΔE-E CsI/SSD-telescope was used to determination the angular range of emitted reaction particles. It allowed an improvement in the energy resolution of the telescope by decreasing the kinematical broadening of the missing energy spectra of12C(γ,p)11B reaction, and enabling more accurate separation of exited states of resid

The effect of different exercise intensities on health related quality of life in people classified as obese

Aims: To investigate how training intensity influences HRQoL in people classified as obese, if HRQoL changes are related to changes in weight or aerobic capacity, and to define minimal clinically important difference (MCID).Methodology: Participants (BMI ≥35 kg/m2) randomized into high-intensity training (n = 49), moderate intensity training (n = 39), or no training (n = 22), completed the SF-36 q

Effects of intense pulsed light in microstomia in patients with systemic sclerosis : A pilot study

Introduction: The effects of intense pulsed light (IPL) on collagen structures are well known in the treatment of photodamaged skin. Objective: The objective of this study was to investigate the effect of IPL on sclerotic skin by treating patients with microstomia due to systemic sclerosis. Methods and materials: 13 patients all with microstomia and systemic sclerosis were treated with IPL, PR (53

Prostatacancercentrum - navet i framtidens prostatacancersjukvård

Prostate cancer is the most common form of cancer in Sweden. The past decade has seen a tremendous development of new methods for diagnosing, staging, treating and rehabilitating men with suspicious or confirmed prostate cancer. This development necessitates a multidisciplinary and multiprofessional approach to the management of men with suspicious or confirmed prostate cancer. A recent survey sho

Precision diagnostics : moving towards protein biomarker signatures of clinical utility in cancer

Interest in precision diagnostics has been fuelled by the concept that early detection of cancer would benefit patients; that is, if detected early, more tumours should be resectable and treatment more efficacious. Serum contains massive amounts of potentially diagnostic information, and affinity proteomics has risen as an accurate approach to decipher this, to generate actionable information that

Properties of the 4-Kallikrein Panel Outside the Diagnostic Gray Zone : Meta-Analysis of Patients with Positive Digital Rectal Examination or Prostate Specific Antigen 10 ng/ml and Above

Purpose: The 4-kallikrein panel, commercially available as the 4Kscore™, is a reflex test for prostate cancer early detection that has been extensively validated in multiple international cohorts. It has been suggested that use of such reflex tests be limited to those with prostate specific antigen less than 10 ng/ml and negative digital rectal examination. We aimed to determine the value of the p

The musical present: A polyphonic philosophical investigation

How can music education be enriched by the concept of time? This article is based on the assumption that the present moment, the musical ‘now’, is of the utmost importance not only to the musical performer or listener but to the musical learner and teacher as well. It aims at a philosophical discussion and conceptual clarification of a number of issues of time that are considered to be crucial to How can music education be enriched by the concept of time? This article is based on the assumption that the present moment, the musical ‘now’, is of the utmost importance not only to the musical performer or listener but to the musical learner and teacher as well. It aims at a philosophical discussion and conceptual clarification of a number of issues of time that are considered to be crucial to

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls

Objective: To explore whether children diagnosed with type 1 diabetes during islet autoantibody surveillance through The Environmental Determinants of Diabetes in the Young (TEDDY) study retain greater islet function than children diagnosed through the community. Methods: TEDDY children identified at birth with high-risk human leukocyte antigen and followed every 3months until diabetes diagnosis w

Algorithms for the treatment of motor problems in Parkinson's disease

Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algori