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Treatment outcome with pencillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bactearemi

An increasing proportion of penicillin-susceptible Staphylococcus aureus (PSSA) has been reported over the last years. The aim of this retrospective study was to compare penicillin G with cloxacillin in the treatment of PSSA bloodstream infections. The primary outcome was the mortality rate after 90 days and the secondary outcome was the development of treatment complications of varying severity.

Phase-matched extreme-ultraviolet frequency-comb generation

Extreme ultraviolet (XUV) laser radiation is commonly produced via high-harmonic generation (HHG) in gases. The lasers that drive this process typically operate at low pulse repetition rates (10 MHz) necessary. Unfortunately, at high repetition rates, plasma accumulates in the XUV generation region and prevents phase-matching, resulting in low HHG efficiency. We use high-temperature gas mixtures t

Vertical test results on ESS medium and high beta elliptical cavity prototypes equipped with helium tank

The ESS elliptical superconducting Linac consists of two types of 704.42 MHz cavities, medium and high beta, to accelerate the beam from 216 MeV (spoke cavity Linac) up to the final energy at 2 GeV. The last Linac optimization, called Optimus+[1], has been carried out taking into account the limitations of SRF cavity performance (field emission). The medium and high-beta parts of the Linac are com

Phobos base : Concept of operations and architecture for a permanent human presence on the Martian moon Phobos

This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i

Climate Policy and Financial Markets

Climate change represents a serious, as-yet-unresolved global commons problem. After decades of international climate negotiations, 195 nations adopted the Paris climate agreement in December 2015. The subsequent election of Donald Trump as US president in 2016 was seen as a setback for climate policy. However, evaluating the impacts of both events is difficult because their results in terms of mi

Search for a heavy charged boson in events with a charged lepton and missing transverse momentum from pp collisions at s =13 TeV with the ATLAS detector

A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb-1 of proton-proton collisions at s=13 TeV collected with the ATLAS detector at the LHC during 2015-2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distr

Sex differences in blood-based biomarkers in individuals with autosomal dominant Alzheimer's disease

BACKGROUND: Blood-based biomarkers are a promising tool for early detection of Alzheimer's disease (AD). We recently showed that individuals with autosomal-dominant AD due to the E280A mutation in the presenilin1 gene (PSEN1) showed elevated levels of plasma tau phosphorylated at threonine 217 (P-tau217) and neurofilament light chain (NfL), as early as approximately 20 years before clinical onset.

Search for long-lived neutral particles produced in pp collisions at s =13 TeV decaying into displaced hadronic jets in the ATLAS inner detector and muon spectrometer

A search is presented for pair production of long-lived neutral particles using 33 fb-1 of s=13 TeV proton-proton collision data, collected during 2016 by the ATLAS detector at the LHC. This search focuses on a topology in which one long-lived particle decays in the ATLAS inner detector and the other decays in the muon spectrometer. Special techniques are employed to reconstruct the displaced trac

Genetic influence during the early phases of Alzheimer's disease on longitudinal cognitive impairment

BACKGROUND: The rate of cognitive decline in the early stages of Alzheimer's disease (AD) is variable, which may be partly due to genetic factors. We therefore investigated genetic predictors of longitudinal cognitive decline in AD. METHOD: In the Swedish BioFINDER study, we used polygenic scores (PGS) (of AD, intelligence and educational attainment), and genetic variants (in a genome-wide associa

Measurement of the cross-section and charge asymmetry of W bosons produced in proton–proton collisions at √s=8TeV with the ATLAS detector

This paper presents measurements of the W+→ μ+ν and W-→ μ-ν cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton–proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2fb-1. The precision of the cross-section meas

Scanning the solutions for the sustainable supply of forest ecosystem services in Europe

Forests are key components of European multifunctional landscapes and supply numerous forest ecosystem services (FES) fundamental to human well-being. The sustainable provision of FES has the potential to provide responses to major societal challenges, such as climate change, biodiversity loss, or rural development. To identify suitable strategies for the future sustenance of FES, we performed a s

Evidence for electroweak production of two jets in association with a Zγ pair in pp collisions at s=13 TeV with the ATLAS detector

Evidence for electroweak production of two jets in association with a Zγ pair in s=13 TeV proton–proton collisions at the Large Hadron Collider is presented. The analysis uses data collected by the ATLAS detector in 2015 and 2016 that corresponds to an integrated luminosity of 36.1fb−1. Events that contain a Z boson candidate decaying leptonically into either e+e− or μ+μ−, a photon, and two jets a

Genetic interaction study of Alzheimer's disease quantitative biomarkers : A polygenic risk score analysis and evaluation

BACKGROUND: Relationship between genetic factors and pathological features of Alzheimer's disease (AD) may be studied with biomarker, using both polygenic risk scores (PRSs), as well as individual genetic variants in genome-wide association studies (GWAS). METHOD: In the Swedish BioFINDER study, we used a priori PRS for AD based on findings in recent GWAS, and AD related biomarkers in cerebrospina

Production of (anti-) He 3 and (anti-) H 3 in p-Pb collisions at sNN =5.02 TeV

The transverse momentum (pT) differential yields of (anti-)He3 and (anti-)H3 measured in p-Pb collisions at sNN = 5.02 TeV with ALICE at the Large Hadron Collider (LHC) are presented. The ratios of the pT-integrated yields of (anti-)He3 and (anti-)H3 to the proton yields are reported, as well as the pT dependence of the coalescence parameters B3 for (anti-)He3 and (anti-)H3. For (anti-)He3, the re

Measurement of soft-drop jet observables in pp collisions with the ATLAS detector at s =13 TeV

Jet substructure quantities are measured using jets groomed with the soft-drop grooming procedure in dijet events from 32.9 fb-1 of pp collisions collected with the ATLAS detector at s=13 TeV. These observables are sensitive to a wide range of QCD phenomena. Some observables, such as the jet mass and opening angle between the two subjets which pass the soft-drop condition, can be described by a hi

Okunnig kritik mot vår rapport om att lockdowns hade liten effekt

Joacim Rocklövs angrepp på rapporten som jag och två medarbetare har publicerat som visar att nedstängningarna inte har haft nämnvärd effekt på dödligheten i corona, är okunnigt, alldeles för snävt och missvisande, skriver Lars Jonung, professor emeritus i nationalekonomi.

A strategy for a general search for new phenomena using data-derived signal regions and its application within the ATLAS experiment

This paper describes a strategy for a general search used by the ATLAS Collaboration to find potential indications of new physics. Events are classified according to their final state into many event classes. For each event class an automated search algorithm tests whether the data are compatible with the Monte Carlo simulated expectation in several distributions sensitive to the effects of new ph

Musik för klimatet

Syftet med hemsidan är att presentera vetenskapliga artiklar inom miljö- och hållbarhetsforskning genom ett samspel mellan musik och text. Vi hoppas på detta sätt att kunna tillgängliggöra dessa fakta och frågeställningar för en bredare publik. På ett okonventionellt och nyskapande vis, genom att kombinera musik och illustrationer/recitation, vill vi föra ut budskapet om, och öka intresset för, hu

Severe infections in patients with ANCA-associated vasculitis treated with rituximab

Objectives: Rituximab (RTX) is an anti-CD20 antibody that selectively depletes B cells and has emerged as a therapy for ANCA-associated vasculitis (AAV) during the past decade. This study sought to quantify and determine potential risk factors for severe infections in AAV patients treated with RTX at rheumatology clinics in Mexico City, Mexico and Lund, Sweden. Methods: The study consisted of a re