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Uses of wonder in popular science : Cosmos: A Personal Voyage and the origin of life

This paper analyses the use of wonder in the TV-series Cosmos: A Personal Voyage (1980). Popular science has been studied extensively (e.g. Broks 2006; Leane 2007; Perrault 2013), and wonder has been studied moderately (e.g. Daston & Park 1998; Fuller 2006; Vasalou 2015). However, there are very few studies of wonder in popular science. This paper explores how and why wonder is used in Cosmos,

Filmhäftet 117

Innehåll: Ledare (Michael Tapper), (Un)Hollow Man: Intervju med Paul Verhoeven (Xavier Mendik), Ännu lägre instinkter: Hollow Man (IQ Hunter), Livet är en fest!: Amerikansk high school-film (Robin Wood), Garbo 1:2 (Richard Lippe), Cool Britannia: Bridget Jones och den nya brittiska filmen (Daniel Sandström). Recensioner: bio, böcker.

Isolation and characterization of primary bone marrow mesenchymal stromal cells

Bone marrow (BM) contains a rare population of mesenchymal stromal cells (MSCs), which have been characterized as nonhematopoietic skeletal progenitor cells with central importance for the hematopoietic microenvironment. Classically, MSCs are isolated by plastic adherence and subsequent culture. However, as cultured stromal cells differ from their in vivo progenitors, it is important to identify t

Calculation of Borehole Thermal Resistance

The borehole thermal resistance – that is, the thermal resistance between the fluid in the U-tube and the borehole wall – is a key performance characteristic of a closed-loop borehole ground heat exchanger. Lower borehole thermal resistance leads to better system performance. Since the original identification of the concept borehole thermal resistance by Mogensen (1983), there have been numerous m

Fall-related activity avoidance in relation to a history of falls or near falls, fear of falling and disease severity in people with Parkinson's disease

Background: There is limited knowledge concerning fall-related activity avoidance in people with Parkinson's disease (PD); such knowledge would be of importance for the development of more efficient PD-care and rehabilitation. This study aimed to examine how fall-related activity avoidance relates to a history of self-reported falls/near falls and fear of falling (FOF) as well as to disease severi

Alterations of diffusion kurtosis and neurite density measures in deep grey matter and white matter in Parkinson's disease

In Parkinson's disease (PD), pathological microstructural changes occur and such changes might be detected using diffusion magnetic resonance imaging (dMRI). However, it is unclear whether dMRI improves PD diagnosis or helps differentiating between phenotypes, such as postural instability gait difficulty (PIGD) and tremor dominant (TD) PD. We included105 patients with PD and 44 healthy controls (H

Smoking, smoking cessation, and fracture risk in elderly women followed for 10 years

Summary: This study examines the impact of smoking and smoking cessation on fracture risk in 75-year-old women followed for 10 years. Smoking increased fracture risk, especially for vertebral fractures. Smoking cessation decreased the risk for vertebral fractures but not for other fracture types. Introduction: The purpose of this study was to examine effects of smoking and smoking cessation on fra

Dual actions of apolipoprotein A-I on glucose-stimulated insulin secretion and insulin-independent peripheral tissue glucose uptake lead to increased heart and skeletal muscle glucose disposal

Apolipoprotein A-I (apoA-I) of HDL is central to the transport of cholesterol in circulation. ApoA-I also provides glucose control with described in vitro effects of apoA-I on β-cell insulin secretion and muscle glucose uptake. In addition, apoA-I injections in insulin-resistant diet-induced obese (DIO) mice lead to increased glucose-stimulated insulin secretion (GSIS) and peripheral tissue glucos

Home- or Institutional Hemodialysis? - a Matched Pair-Cohort Study Comparing Survival and Some Modifiable Factors Related to Survival

Background/Aims: Survival for dialysis patients is poor. Earlier studies have shown better survival in home-hemodialysis (HHD). The aims of this study are to compare survival for matched patients with HHD and institutional hemodialysis (IHD) and to elucidate the effect on factors related to survival such as hyperphosphatemia, fluid overload and anemia. Methods: In this retrospective, observational

Negative-Ion/Positive-Ion Coincidence Yields of Core-Excited Water

We report yields of mass-resolved negative ions and positive ions measured in coincidence after core-excitation of water molecules. The analysis of negative-ion/positive-ion and negative-ion/positive-ion/positive-ion coincidence events provides new information on pathways leading to negative ion production, enhancing the present understanding of the dissociation processes of the water molecule. Di

The outcome of lumbar disc herniation surgery is worse in old adults than in young adults : A study of 14,090 individuals in the Swedish Spine Surgery Register (SweSpine)

Background and purpose — The outcome of surgical treatment of lumbar disc herniation (LDH) has been thoroughly evaluated in middle-aged patients, but less so in elderly patients. Patients and methods — With validated patient-reported outcome measures (PROMs) and using SweSpine (the national Swedish Spine Surgery Register), we analyzed the preoperative clinical status of LDH patients and the 1-year

The qualities needed for a successful collaboration : A contribution to the conceptual understanding of collaboration for efficient public transport

The creation of an efficient public transport system requires collaborations between formal independent organizations. This paper examines collaborations between public and private organizations and passengers, with the aim of contributing to the conceptual understanding of collaborations on public transport. The study begins by describing previous research on collaboration in the public transport

Numerical study on reducing building vibrations by foundation improvement

Vibration disturbances in buildings may stem from ambient sources, such as motorway traffic, or from internal sources such as people walking inside the building. Vibrations can exceed requirements for sensitive equipment or cause annoyance to humans and therefore the vibrations may need to be reduced. Vibrations from both external and internal sources can be reduced by modifying the properties of

Risk of solid tumors and hematological malignancy in persons with Turner and Klinefelter syndromes : A national cohort study

The risk of solid and hematological malignancy in patients with Turner syndrome, characterized by X chromosome monosomy in women, and Klinefelter syndrome, characterized with two and more X chromosomes in men, is not well established, but such evidence may have etiological implications on cancer development. We identified a total of 1,409 women with Turner syndrome and 1,085 men with Klinefelter s

Patient-reported outcome after radical cystectomy : translation and psychometric validation of the Swedish version of the Functional Assessment of Cancer Therapy Scale Vanderbilt Cystectomy Index

Objective: The aim of this study was to translate and validate the Swedish version of the Functional Assessment of Cancer Therapy Scale – Vanderbilt Cystectomy Index (FACT-VCI). Materials and methods: For adaptation into Swedish, a multiprofessional team was used for translation including cultural adjustment, followed by back-translation. Test and retest in 10 individuals was followed by assessing

Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition : Part 1 - Fields of Precision Nutrition

Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient requirements, metabolism and response to nutritional and dietary interventions. Indeed, individuals respond differently to lifestyle interventions (diet, physical activity, smoking, etc.). The sequencing of the human genome and subsequent increased knowledge regarding human genetic variation is contrib

Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells : Dual interference of this loop more effectively impairs melanoma cell invasion

Increased expression and signalling of WNT5A and interleukin-6 (IL-6) have both been shown to promote melanoma progression. Here, we investigated the proposed existence of a WNT5A-IL-6 positive feedback loop that drives melanoma migration and invasion. First, the HOPP algorithm revealed that the invasive phenotype of cultured melanoma cells was significantly correlated with increased expression of

Cartilage proteoglycans

Proteoglycans are key components of the cartilage extracellular matrix and essential for normal tissue function. The core protein and the glycosaminoglycan chains both contribute to function and provide different properties of the individual proteoglycans. This review is focused on the two main families of cartilage proteoglycans.The first of these is the lectican family, including aggrecan, versi

Neighborhood linking social capital as a predictor of drug abuse : A Swedish national cohort study

Aims This study examines the association between the incidence of drug abuse (DA) and linking (communal) social capital, a theoretical concept describing the amount of trust between individuals and societal institutions. Methods We present results from an 8-year population-based cohort study that followed all residents in Sweden, aged 15–44, from 2003 through 2010, for a total of 1,700,896 men and

Managing nature in the home garden

Despite their rootedness, plants do move and are moved between different places in the garden, and from one garden to another. In many private gardens there are plants with a history, and owners who tell stories about how they were brought in from a different location, for example from an old relative or from a journey. These plants are often regarded as relics or souvenirs, and receive special at